Control of Dkk-1 ameliorates chondrocyte apoptosis, cartilage destruction, and subchondral bone deterioration in osteoarthritic knees

Dickkopf-1 Enhances Inflammatory Interaction Between Platelets and Endothelial Cells and Shows Increased Expression in Atherosclerosis

(2009) Thor Ueland et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Cleavage of Type II Collagen by Cathepsin K in Human Osteoarthritic Cartilage

(2008) Valeria M. Dejica et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of β‐catenin signaling in articular chondrocytes results in articular cartilage destruction

(2008) Mei Zhu et al.   ARTHRITIS AND RHEUMATISM

Cell-based resurfacing of large cartilage defects: Long-term evaluation of grafts from autologous transgene-activated periosteal cells in a porcine model of osteoarthritis

(2008) Kolja Gelse et al.   ARTHRITIS AND RHEUMATISM

Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: A longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice

(2008) Wei Yao et al.   ARTHRITIS AND RHEUMATISM

Myeloma-derived Dickkopf-1 disrupts Wnt-regulated osteoprotegerin and RANKL production by osteoblasts: a potential mechanism underlying osteolytic bone lesions in multiple myeloma

(2008) Y.-W. Qiang et al.   BLOOD

The role of Dickkopf-1 in bone development, homeostasis, and disease

(2008) J. J. Pinzone et al.   BLOOD

Prostate Cancer Induces Bone Metastasis through Wnt-Induced Bone Morphogenetic Protein-Dependent and Independent Mechanisms

(2008) J. Dai et al.   CANCER RESEARCH

Modulation of Dickkopf-1 Attenuates Glucocorticoid Induction of Osteoblast Apoptosis, Adipocytic Differentiation, and Bone Mass Loss

(2008) Feng-Sheng Wang et al.   ENDOCRINOLOGY

Constitutive Activation of Phosphatidylinositol 3-Kinase Signaling Pathway Down-regulates TLR4-mediated Tumor Necrosis Factor-α Release in Alveolar Macrophages from Asymptomatic HIV-positive Personsin Vitro

(2008) Souvenir D. Tachado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of β-Catenin Signaling in Articular Chondrocytes Leads to Osteoarthritis-Like Phenotype in Adult β-Catenin Conditional Activation Mice

(2008) Mei Zhu et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Inhibition of  -catenin signaling causes defects in postnatal cartilage development

(2008) M. Chen et al.   JOURNAL OF CELL SCIENCE

Wnt/β-catenin signaling stimulates matrix catabolic genes and activity in articular chondrocytes: its possible role in joint degeneration

(2008) Takahito Yuasa et al.   LABORATORY INVESTIGATION

Targeted Disruption of the Wnt Regulator Kremen Induces Limb Defects and High Bone Density

(2008) K. Ellwanger et al.   MOLECULAR AND CELLULAR BIOLOGY

Wnt-3a and Dickkopf-1 Stimulate Neurite Outgrowth in Ewing Tumor Cells via a Frizzled3- and c-Jun N-Terminal Kinase-Dependent Mechanism

(2008) Y. Endo et al.   MOLECULAR AND CELLULAR BIOLOGY

Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts

(2008) J.M. Kerkhof et al.   OSTEOARTHRITIS AND CARTILAGE

Inflammation induction of Dickkopf-1 mediates chondrocyte apoptosis in osteoarthritic joint

(2008) L.-H. Weng et al.   OSTEOARTHRITIS AND CARTILAGE

The protective effect of OP-1 on articular cartilage in the development of osteoarthritis

(2007) N. Badlani et al.   OSTEOARTHRITIS AND CARTILAGE

Cartilage damage pattern in relation to subchondral plate thickness in a collagenase-induced model of osteoarthritis

(2007) S.M. Botter et al.   OSTEOARTHRITIS AND CARTILAGE