Carboxyl Terminus of ADAMTS13 Directly Inhibits Platelet Aggregation and Ultra Large von Willebrand Factor String Formation Under Flow in a Free-Thiol–Dependent Manner

Human Complement Factor H Is a Reductase for Large Soluble von Willebrand Factor Multimers—Brief Report

(2013) Leticia Nolasco et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Essential Domains of A Disintegrin and Metalloprotease With Thrombospondin Type 1 Repeats-13 Metalloprotease Required for Modulation of Arterial Thrombosis

(2011) Juan Xiao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13)

(2011) Y. Xiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amino acid residues Arg659, Arg660, and Tyr661 in the spacer domain of ADAMTS13 are critical for cleavage of von Willebrand factor

(2010) S.-Y. Jin et al.   BLOOD

Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice

(2010) J. Huang et al.   BLOOD

Multiple domains of ADAMTS13 are targeted by autoantibodies against ADAMTS13 in patients with acquired idiopathic thrombotic thrombocytopenic purpura

(2010) X. L. Zheng et al.   HAEMATOLOGICA

Disulfide bond reduction of von Willebrand factor by ADAMTS-13

(2010) H.-C. YEH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Leukocyte proteases cleave von Willebrand factor at or near the ADAMTS13 cleavage site

(2009) T. J. Raife et al.   BLOOD

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

(2009) W. Pos et al.   BLOOD

von Willebrand factor cleaved from endothelial cells by ADAMTS13 remains ultralarge in size

(2009) S.-Y. JIN et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Species-dependent variability of ADAMTS13-mediated proteolysis of human recombinant von Willebrand factor

(2009) K. VARADI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor

(2009) M. Akiyama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flow-based measurements of von Willebrand factor (VWF) function: Binding to collagen and platelet adhesion under physiological shear rate

(2009) Birte Fuchs et al.   THROMBOSIS RESEARCH

Pathogenesis of Thrombotic Microangiopathies

(2008) X. Long Zheng et al.   Annual Review of Pathology-Mechanisms of Disease

Extensive contacts between ADAMTS13 exosites and von Willebrand factor domain A2 contribute to substrate specificity

(2008) W. Gao et al.   BLOOD

Correction of ADAMTS13 Deficiency by In Utero Gene Transfer of Lentiviral Vector encoding ADAMTS13 Genes

(2008) Masami Niiya et al.   MOLECULAR THERAPY