Activation of Liver X Receptor Decreases Atherosclerosis in Ldlr −/− Mice in the Absence of ATP-Binding Cassette Transporters A1 and G1 in Myeloid Cells

Deficiency of ATP-Binding Cassette Transporters A1 and G1 in Macrophages Increases Inflammation and Accelerates Atherosclerosis in Mice

(2013) Marit Westerterp et al.   CIRCULATION RESEARCH

HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders

(2013) Emmanuel L. Gautier et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Feedback Regulation of Cholesterol Uptake by the LXR–IDOL–LDLR Axis

(2012) Li Zhang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Intestinal Specific LXR Activation Stimulates Reverse Cholesterol Transport and Protects from Atherosclerosis

(2010) Giuseppe Lo Sasso et al.   Cell Metabolism

ATP-Binding Cassette Transporters and HDL Suppress Hematopoietic Stem Cell Proliferation

(2010) L. Yvan-Charvet et al.   SCIENCE

Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis

(2009) Darren L. Asquith et al.   ARTHRITIS AND RHEUMATISM

The Benzenesulfoamide T0901317 [N-(2,2,2-Trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] Is a Novel Retinoic Acid Receptor-Related Orphan Receptor- /  Inverse Agonist

(2009) N. Kumar et al.   MOLECULAR PHARMACOLOGY

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE

Increased Inflammatory Gene Expression in ABC Transporter–Deficient Macrophages

(2008) Laurent Yvan-Charvet et al.   CIRCULATION

The LXR agonist T0901317 promotes the reverse cholesterol transport from macrophages by increasing plasma efflux potential

(2008) Ilaria Zanotti et al.   JOURNAL OF LIPID RESEARCH

Structure-Guided Design ofN-Phenyl Tertiary Amines as Transrepression-Selective Liver X Receptor Modulators with Anti-Inflammatory Activity

(2008) Esther Y. Chao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combined Deletion of Macrophage ABCA1 and ABCG1 Leads to Massive Lipid Accumulation in Tissue Macrophages and Distinct Atherosclerosis at Relatively Low Plasma Cholesterol Levels

(2007) Ruud Out et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY