Transition From Obesity to Metabolic Syndrome Is Associated With Altered Myocardial Autophagy and Apoptosis

Hypercholesterolemia is associated with hyperactive cardiac mTORC1 and mTORC2 signaling

(2011) Hilary P. Glazer et al.   CELL CYCLE

Rhesus Macaques Develop Metabolic Syndrome With Reversible Vascular Dysfunction Responsive to Pioglitazone

(2011) Xiuqin Zhang et al.   CIRCULATION

Prevention of Overweight/Obesity as a Strategy to Optimize Cardiovascular Health

(2011) Marc-Andre Cornier et al.   CIRCULATION

A Murine Model of Isolated Cardiac Steatosis Leads to Cardiomyopathy

(2011) Denis J. Glenn et al.   HYPERTENSION

Role of Cardiac Steatosis and Lipotoxicity in Obesity Cardiomyopathy

(2011) Yingmei Zhang et al.   HYPERTENSION

Autophagy as a therapeutic target in cardiovascular disease

(2011) Andriy Nemchenko et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Myocardial autophagy activation and suppressed survival signaling is associated with insulin resistance in fructose-fed mice

(2011) Kimberley M. Mellor et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Early experimental hypertension preserves the myocardial microvasculature but aggravates cardiac injury distal to chronic coronary artery obstruction

(2010) Victor Hugo Urbieta Caceres et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autophagy

(2010) Lijun Zhou et al.   Autophagy

Effects of Obesity and Subsequent Weight Reduction on Left Ventricular Function

(2010) Mohan Lakhani et al.   Cardiology in Review

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Vitamin B1 Analog Benfotiamine Prevents Diabetes-Induced Diastolic Dysfunction and Heart Failure Through Akt/Pim-1–Mediated Survival Pathway

(2010) Rajesh G. Katare et al.   Circulation-Heart Failure

Downregulation of the Longevity-Associated Protein Sirtuin 1 in Insulin Resistance and Metabolic Syndrome: Potential Biochemical Mechanisms

(2010) S. V. de Kreutzenberg et al.   DIABETES

Determinations of Renal Cortical and Medullary Oxygenation Using Blood Oxygen Level-Dependent Magnetic Resonance Imaging and Selective Diuretics

(2010) Lizette Warner et al.   INVESTIGATIVE RADIOLOGY

Prevalence and Trends in Obesity Among US Adults, 1999-2008

(2010) Katherine M. Flegal   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

High-carbohydrate, High-fat Diet–induced Metabolic Syndrome and Cardiovascular Remodeling in Rats

(2010) Sunil K. Panchal et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Activation of p53 enhances apoptosis and insulin resistance in a rat model of alcoholic liver disease

(2010) Zoltan Derdak et al.   JOURNAL OF HEPATOLOGY

Cannabidiol Attenuates Cardiac Dysfunction, Oxidative Stress, Fibrosis, and Inflammatory and Cell Death Signaling Pathways in Diabetic Cardiomyopathy

(2010) Mohanraj Rajesh et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Progressive Renal Vascular Proliferation and Injury in Obese Zucker Rats

(2010) RADU ILIESCU et al.   MICROCIRCULATION

SIRT1 Negatively Regulates the Mammalian Target of Rapamycin

(2010) Hiyaa Singhee Ghosh et al.   PLoS One

Myocardial microvascular function during acute coronary artery stenosis: effect of hypertension and hypercholesterolaemia

(2009) X.-Y. Zhu et al.   CARDIOVASCULAR RESEARCH

Nutrient Stress Activates Inflammation and Reduces Glucose Metabolism by Suppressing AMP-Activated Protein Kinase in the Heart

(2009) H. J. Ko et al.   DIABETES

Adipocyte Apoptosis, a Link between Obesity, Insulin Resistance, and Hepatic Steatosis

(2009) Naim Alkhouri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Relationship of Ectopic Lipid Accumulation to Cardiac and Vascular Function in Obesity and Metabolic Syndrome

(2009) Frederick L. Ruberg et al.   Obesity

Insulin-Resistant Cardiomyopathy

(2008) Ronald M. Witteles et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY