Disrupting the EMMPRIN (CD147)–Cyclophilin A Interaction Reduces Infarct Size and Preserves Systolic Function After Myocardial Ischemia and Reperfusion

EMMPRIN: A Novel Regulator of Leukocyte Transmigration into the CNS in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

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Cyclosporine A at Reperfusion Reduces Infarct Size in Pigs

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TIMP2 Deficiency Accelerates Adverse Post–Myocardial Infarction Remodeling Because of Enhanced MT1-MMP Activity Despite Lack of MMP2 Activation

(2010) Vijay Kandalam et al.   CIRCULATION RESEARCH

Cyclophilin A is an inflammatory mediator that promotes atherosclerosis in apolipoprotein E–deficient mice

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A New Monocyte Chemotactic Protein-1/Chemokine CC Motif Ligand-2 Competitor Limiting Neointima Formation and Myocardial Ischemia/Reperfusion Injury in Mice

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Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration

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EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation

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EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2 -mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2

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Myocardial Ischemia/Reperfusion Injury Is Mediated by Leukocytic Toll-Like Receptor-2 and Reduced by Systemic Administration of a Novel Anti–Toll-Like Receptor-2 Antibody

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Contribution of Cyclophilin A to the Regulation of Inflammatory Processes in Rheumatoid Arthritis

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Cyclophilin A enhances vascular oxidative stress and the development of angiotensin II–induced aortic aneurysms

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Cardioprotection

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Ischemic Postconditioning in Pigs

(2008) Andreas Skyschally et al.   CIRCULATION RESEARCH

Targeting the chemotactic function of CD147 reduces collagen-induced arthritis

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MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

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Effect of Cyclosporine on Reperfusion Injury in Acute Myocardial Infarction

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Cyclophilin A up-regulates MMP-9 expression and adhesion of monocytes/macrophages via CD147 signalling pathway in rheumatoid arthritis

(2008) Y. Yang et al.   RHEUMATOLOGY

Extracellular Matrix Metalloproteinase Inducer (CD147) Is a Novel Receptor on Platelets, Activates Platelets, and Augments Nuclear Factor κB–Dependent Inflammation in Monocytes

(2007) Roland Schmidt et al.   CIRCULATION RESEARCH

Impaired platelet function reduces myocardial infarct size in Gαq knock-out mice in vivo

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