Article
Toxicology
Alva Hansson, Gregory Rankin, Oskari Uski, Maria Friberg, Jamshid Pourazar, Robert Lindgren, Natxo Garcia-Lopez, Christoffer Boman, Thomas Sandstrom, Annelie Behndig, Ala Muala
Summary: This study found that exposure to incomplete combustion wood smoke did not induce acute airway inflammation within 6 hours, except for an increase in eosinophils. However, there were indications of a cytotoxic reaction with increased lactate dehydrogenase levels, reduced cell viability, and impaired alveolar macrophage phagocytic capacity. These findings are consistent with previous research and may provide evidence for the increased susceptibility to infections caused by biomass smoke exposure.
PARTICLE AND FIBRE TOXICOLOGY
(2023)
Article
Construction & Building Technology
Laura Nicolaou, Magdalena Fandino-Del-Rio, Kirsten Koehler, William Checkley
Summary: This study characterized particle size distribution from biomass-related pollution and assessed lung-deposited doses using multiple-path deposition modeling. Results showed high PM2.5 concentrations in kitchen and personal exposures, with a primary accumulation mode at 0.21 µm and a secondary coarse mode at 3.17 µm. Additionally, the study provides unique data on lung deposition of biomass smoke.
Article
Multidisciplinary Sciences
Yosri Akl, Eman Kamal Ibrahim, Tareq Muhammad Algarf, Rasha R. Mostafa, Hoda M. Abdel-Hamid, Asmaa Ibrahim Muhammed
Summary: The purpose of this study was to investigate nasal histopathological changes in HP patients and identify any shared pathological features between the upper airways and HP. The study included 40 HP patients who underwent thorough evaluations and nasal mucosal biopsy. The results showed that 87.5% of HP patients had chronic inflammation of the nasal mucosa, with predominant lymphocytic infiltration in 72.5% of patients. Additionally, 77.5% of patients had a high burden of sinonasal symptoms, which was positively associated with cough severity.
SCIENTIFIC REPORTS
(2023)
Article
Environmental Sciences
Larisa M. Sosedova, Vera A. Vokina, Mikhail A. Novikov, Viktor S. Rukavishnikov, Elizaveta S. Andreeva, Olga M. Zhurba, Anton N. Alekseenko
Summary: The study examined the effects of paternal biomass smoke exposure on offspring's behavior and cognitive abilities, finding that immediate offspring showed decreased exploration, locomotion, spatial navigation, and increased anxiety levels after exposure. Long-term effects on cognitive functions were more significant in female offspring.
Article
Engineering, Environmental
Lauren E. Koval, Celeste K. Carberry, Yong Ho Kim, Elena McDermott, Hadley Hartwell, Ilona Jaspers, M. Ian Gilmour, Julia E. Rager
Summary: The prevalence of wildfires is increasing globally, resulting in increased disease risk. This study grouped biomass smoke exposures from different fuels and combustion conditions based on similar transcriptional response profiles, providing insights for health risk evaluations. Fires of flaming peat, flaming eucalyptus, and smoldering eucalyptus induced the strongest responses.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Review
Food Science & Technology
Bo He, Qi Zhang, Yu Guo, Ying Ao, Kai Tie, Hao Xiao, Liaobin Chen, Dan Xu, Hui Wang
Summary: Exposure to smoking during pregnancy affects fetal development and increases susceptibility to metabolic diseases in adulthood. The mechanism involves both direct effects of nicotine and neuroendocrine-metabolic programming mediated by maternal glucocorticoid over-exposure.
FOOD AND CHEMICAL TOXICOLOGY
(2022)
Review
Physiology
Marta Schiliro, Elizabeth R. Vogel, Lucia Paolini, Christina M. Pabelick
Summary: The detrimental effects of tobacco exposure on children's health are well known, and the prevalence of secondhand or direct cigarette smoke exposure in the pediatric population has not significantly decreased over time. Additionally, the rapid increase in e-cigarette use among adolescents has raised public health concerns.
FRONTIERS IN PHYSIOLOGY
(2021)
Review
Cell Biology
Blanca Ortiz-Quintero, Israel Martinez-Espinosa, Rogelio Perez-Padilla
Summary: Chronic exposure to indoor biomass smoke from solid organic fuels is a major cause of disease burden worldwide. This exposure is associated with chronic respiratory diseases such as COPD and chronic bronchitis. Despite the high burden of biomass-associated COPD, the pathogenic mechanisms underlying its development are poorly understood.
Article
Environmental Sciences
Naman Paul, Jiayun Yao, Kathleen E. McLean, David M. Stieb, Sarah B. Henderson
Summary: Exposure to biomass smoke is associated with various acute and chronic health outcomes. Estimating PM2.5 concentrations is crucial for understanding the health effects of biomass smoke exposure. Researchers have developed a machine learning approach to estimate PM2.5 across populated regions in Canada from 2010 to 2019.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Review
Respiratory System
Sebastian T. Lugg, Aaron Scott, Dhruv Parekh, Babu Naidu, David R. Thickett
Summary: Smoking disrupts the function of alveolar macrophages, increasing the risk of acute lung injury and pulmonary infection.
Article
Respiratory System
Jinglong Chen, Changbin Jiang, Youlan Zheng, Dongxing Zhao, Fan Wu, Zhuxiang Zhao, Jun Zhao, Qing Li, Bing Li, Gongyong Peng, Yumin Zhou, Pixin Ran
Summary: Individuals with COPD exposed to biomass smoke showed different pulmonary and non-pulmonary changes compared to healthy individuals, with COPD patients exhibiting more severe disease progression.
INTERNATIONAL JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2021)
Article
Biochemistry & Molecular Biology
Lynne Rosenberg, Cuining Liu, Rinku Sharma, Cheyret Wood, Carrie A. A. Vyhlidal, Roger Gaedigk, Alvin T. T. Kho, John P. P. Ziniti, Juan C. C. Celedon, Kelan G. G. Tantisira, Scott T. T. Weiss, Michael J. J. McGeachie, Katerina Kechris, Sunita Sharma
Summary: Intrauterine smoke exposure during early childhood may have a negative impact on lung function and asthma susceptibility. This study aimed to investigate the effects of intrauterine smoke exposure on miRNA expression during human lung development and its association with future asthma and allergy risk. The findings suggest that certain miRNAs are dysregulated by intrauterine smoke exposure and may be relevant for subsequent allergy and asthma risk. This study provides important insight into the developmental origins of asthma and allergic disorders.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Environmental Sciences
Edward J. Perkins, Kimberly T. To, Lindsey St Mary, Charles H. Laber, Anthony J. Bednar, Lisa Truong, Robyn L. Tanguay, Natalia Garcia-Reyero
Summary: Dyes Disperse Blue 14, Disperse Red 9, Solvent Red 169, and Solvent Yellow 33 have been found to adversely affect zebrafish embryos, with Disperse Blue 14 and Solvent Yellow 33 having the most significant impact on development and behavior.
Article
Environmental Sciences
Mengyi Jin, Yanzi Wang, Xiaoya An, Honghua Kang, Yixin Wang, Guoliang Wang, Yang Gao, Shuiping Wu, Peter S. Reinach, Zuguo Liu, Yuhua Xue, Cheng Li
Summary: The study showed that exposure to cigarette smoke induces changes in the phenotype and genotype of the corneal epithelium, leading to structural damage and decreased microvilli density, further impacting the integrity of the corneal epithelial barrier. Additionally, it highlights the importance of antioxidant responses in counteracting the effects of cigarette smoke on the ocular surface, providing novel insights into how cigarette smoke damages the corneal epithelium.
ENVIRONMENTAL POLLUTION
(2021)
Article
Medicine, Research & Experimental
Joao Paulo Miguel, Andressa da Cunha Dias, Nathalia Rodrigues Bettini, Samuel Antonio Biajo Amancio de Sousa, Marilia Pereira Lima Durao, Lucas Vaz de Castro Oliveira, Fernanda Monedeiro, Leandra Naira Zambelli Ramalho, Luiz Guilherme S. Branco, Joao Paulo Jacob Sabino, Marina de Toledo Durand
Summary: Chronic exposure to cigarette smoke of 1 or 2 cigarettes/day can lead to systemic changes and autonomic cardiocirculatory dysfunction in rats, especially with exposure to 2 cigarettes/day.
Article
Respiratory System
Aysel Sunnetcioglu, Bunyamin Sertogullarindan, Abdussamet Batur, Irfan Bayram
CLINICAL RESPIRATORY JOURNAL
(2018)
Article
Biochemistry & Molecular Biology
Selami Ekin, Ahmet Arisoy, Hulya Gunbatar, Bunyamin Sertogullarindan, Aysel Sunnetcioglu, Hatice Sezen, Selvi Asker, Hanifi Yildiz
Article
Andrology
F. Beyazal Celiker, L. Tumkaya, T. Mercantepe, G. Turan, A. Yilmaz, M. Beyazal, A. Turan, M. F. Inecikli, M. Kosem
Article
Computer Science, Artificial Intelligence
Mehmet Emin Salman, Gozde Cakirsoy Cakar, Jahongir Azimjonov, Mustafa Kosem, Ismail Hakki Cedimoglu
Summary: An artificial intelligence-based prostate cancer detection and diagnosis system was developed, achieving high accuracy in detection and classification through the use of object detection algorithms. These systems can reduce inter-observer variability among pathologists and help prevent time delays in the diagnosis phase.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
Article
Pathology
Mustafa Kosem, Gupse Turan, Metin Ercan, Ebru Tezcan
Summary: Calcifying fibrous tumor is a rare benign mesenchymal tumor that primarily occurs in the gastrointestinal tract, particularly in the stomach, small bowel, and colon. This tumor is usually associated with chronic inflammation and calcification, but its occurrence in the pancreas has not been reported.
INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY
(2021)
Article
Medicine, General & Internal
Tuba Hacibekiroglu, Yasin Kalpakci, Tugce Nur Yigenoglu, Kubilay Issever, Gulay Trak, Ilhan Hacibekiroglu, Yusuf Aydemir, Hande Toptan, Cenk Sunu, Oguz Karabay, Mustafa Kosem, Mehmet Koroglu
Summary: The study uncovered the presence of SARS-CoV-2 in bone marrow of COVID-19 patients, leading to reactive plasmacytosis and an increase in active monocytes. Flow cytometric analysis may aid scientists in understanding the pathogenesis of SARS-CoV-2 and its impact on hematopoietic cells.
ACTA MEDICA MEDITERRANEA
(2021)
Article
Respiratory System
Betul Ikbal Dogan, Ceyda Mahlec Anar, Bunyamin Sertogullarindan, Muzaffer Onur Turan
Summary: As the COVID-19 pandemic continues, there is increased awareness of uncommon presentations of the disease, such as pneumomediastinum. Recent evidence suggests that this complication can occur in COVID-19 pneumonia, even without mechanical ventilation-related barotrauma. In this study, a patient with COVID-19 pneumonia complicated by pneumomediastinum was presented.
TUBERKULOZ VE TORAKS-TUBERCULOSIS AND THORAX
(2021)
Article
Medicine, General & Internal
Ertugrul Guclu, Aziz Ogutlu, Mustafa Kosem, Unal Erkorkmaz, Oguz Karabay
VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL
(2019)
Article
Medicine, General & Internal
Oguz Karabay, Ertugrul Guclu, Tuba Hacibekiroglu, Mustafa Kosem
VIRAL HEPATIT DERGISI-VIRAL HEPATITIS JOURNAL
(2019)
Article
Respiratory System
Ozge Aydin Guclu, Mehmet Karadag, Yavuz Selim Intepe, Turan Acican, Sertac Arslan, Bunyamin Sertogullarindan
TUBERKULOZ VE TORAK-TUBERCULOSIS AND THORAX
(2019)
Article
Cardiac & Cardiovascular Systems
Tevfik Ozlu, Yilmaz Bulbul, Derya Aydin, Dursun Tatar, Tulin Kuyucu, Fatma Erboy, Handan Inonu Koseoglu, Ceyda Anar, Aysel Sunnetcioglu, Pinar Yildiz Gulhan, Unal Sahin, Aydanur Ekici, Serap Duru, Sevinc Sarinc Ulasli, Ercan Kurtipek, Sibel Gunay, O. Okutan, B. P. Yildiz, P. D. Cetinkaya, S. Arslan, G. Cakmak, A. K. Cirak, N. Sarioglu, N. D. Kocak, U. A. Akturk, M. Demir, T. Kilic, A. Dalli, H. Hezer, N. Altintas, M. Acat, C. E. Dagli, A. Kargi, F. Yakar, G. Kirkil, A. Baccioglu, C. Gedik, Y. S. Intepe, G. Karadeniz, T. Onyilmaz, B. Saylan, S. Baslilar, N. Sariman, S. Ozkurt, S. Arinc, A. Kanbay, E. E. Yazar, Z. Yildirim, E. E. Kadioglu, S. Gul, A. Sengul, S. Berk, O. S. Dikis, O. K. Kurt, Y. Arslan, S. Erol, C. Korkmaz, A. Balaban, Toru U. Erbay, O. Sogukpinar, E. K. Uzaslan, E. Babaoglu, A. Bahadir, S. A. Baris, A. O. Ugurlu, A. H. Ilgazli, F. Fidan, E. Kararmaz, A. Guzel, S. Alzafer, M. Cortuk, I Hocanli, M. G. Ortakoylu, M. S. Erginel, N. Yaman, A. E. Erbaycu, A. Demir, D. Duman, H. Tanriverdi, M. Y. Yavuz, B. Sertogullarindan, S. Ozyurt, E. Bulcun, G. D. Yuce, M. Sariaydin, O. Ayten, M. Bayraktaroglu, S. Tekgul, F. Erel, A. Senyigit, S. B. Kaya, S. Ayik, O. Yazici, A. Akgedik, Z. A. Yasar, E. Hayat, F. Kalpaklioglu, F. Sever, P. Sarac, E. Ugurlu, U. S. Kasapoglu, G. Gunluoglu, N. Y. Demirci, M. Bora, F. Talay, B. Ozkara, M. U. Yilmaz, D. M. Yavsan, E. D. Cetinoglu, M. B. Balcan, T. Ciftci, A. Havan, A. Gok, M. Nizam
ANNALS OF THORACIC MEDICINE
(2019)
Article
Cardiac & Cardiovascular Systems
Bunyamin Sertogullarindan, Ahmet Ufuk Komuroglu, Rifki Ucler, Hulya Gunbatar, Aysel Sunnetcioglu, Erdem Cokluk
ANNALS OF THORACIC MEDICINE
(2019)
Article
Urology & Nephrology
Didar Senocak, Ahmet Bilal Genc, Mehmet Yildirim, Hamad Dheir, Mustafa Kosem, Savas Sipahi
TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL
(2018)
Article
Medicine, Research & Experimental
Hulya Gunbatar, Mehmet Deniz Bulut, Selami Ekin, Bunyamin Sertogullarindan, Aydin Bora, Alpaslan Yavuz, Esma Tamac
INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE
(2016)
Article
Medicine, Research & Experimental
Ahmet Arisoy, Bunyamin Sertogullarindan, Selami Ekin, Mesut Ozgokce, Mehmet Deniz Bulut, Mehmet Tahir Huyut, Sehmus Olmez, Mahfuz Turan
MEDICAL SCIENCE MONITOR
(2016)