The Role and Regulation of mTOR in T-Lymphocyte Function

Negative regulation of mTOR activation by diacylglycerol kinases

(2011) B. K. Gorentla et al.   BLOOD

Regulation of T-cell survival and mitochondrial homeostasis by TSC1

(2011) Thomas F. O'Brien et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Critical Roles of RasGRP1 for Invariant NKT Cell Development

(2011) S. Shen et al.   JOURNAL OF IMMUNOLOGY

The Tuberous Sclerosis Complex-Mammalian Target of Rapamycin Pathway Maintains the Quiescence and Survival of Naive T Cells

(2011) Q. Wu et al.   JOURNAL OF IMMUNOLOGY

Tight Regulation of Diacylglycerol-Mediated Signaling Is Critical for Proper Invariant NKT Cell Development

(2011) S. Shen et al.   JOURNAL OF IMMUNOLOGY

The tumor suppressor Tsc1 enforces quiescence of naive T cells to promote immune homeostasis and function

(2011) Kai Yang et al.   NATURE IMMUNOLOGY

The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2

(2011) Greg M Delgoffe et al.   NATURE IMMUNOLOGY

Mammalian Target of Rapamycin Protein Complex 2 Regulates Differentiation of Th1 and Th2 Cell Subsets via Distinct Signaling Pathways

(2010) Keunwook Lee et al.   IMMUNITY

The mTOR Kinase Determines Effector versus Memory CD8 + T Cell Fate by Regulating the Expression of Transcription Factors T-bet and Eomesodermin

(2010) Rajesh R. Rao et al.   IMMUNITY

Receptor signaling in immune cell development and function

(2010) Xiao-Ping Zhong et al.   IMMUNOLOGIC RESEARCH

A complex interplay between Akt, TSC2 and the two mTOR complexes: Figure 1

(2009) Jingxiang Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The TOR pathway comes of age

(2009) Monique N. Stanfel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

S6K1 deficiency protects against apoptosis in hepatocytes

(2009) Águeda González-Rodriguez et al.   HEPATOLOGY

mTORC1-Activated S6K1 Phosphorylates Rictor on Threonine 1135 and Regulates mTORC2 Signaling

(2009) L.-A. Julien et al.   MOLECULAR AND CELLULAR BIOLOGY

Enhancing CD8 T-cell memory by modulating fatty acid metabolism

(2009) Erika L. Pearce et al.   NATURE

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE

Negative regulators in homeostasis of naïve peripheral T cells

(2008) Jaime F. Modiano et al.   IMMUNOLOGIC RESEARCH

Diacylglycerol kinases in immune cell function and self-tolerance

(2008) Xiao-Ping Zhong et al.   IMMUNOLOGICAL REVIEWS

The TSC1-TSC2 Complex Is Required for Proper Activation of mTOR Complex 2

(2008) J. Huang et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

(2008) Linda V Sinclair et al.   NATURE IMMUNOLOGY

Synergistic control of T cell development and tumor suppression by diacylglycerol kinase   and  

(2008) R. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA