The Transcription Factor PU.1 is a Critical Regulator of Cellular Communication in the Immune System

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

(2011) M. Leddin et al.   BLOOD

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Adult Hematopoiesis is Regulated by TIF1γ, a Repressor of TAL1 and PU.1 Transcriptional Activity

(2011) Sophie Kusy et al.   Cell Stem Cell

The genomic landscapes of inflammation

(2011) G. Natoli et al.   GENES & DEVELOPMENT

CREBBP mutations in relapsed acute lymphoblastic leukaemia

(2011) Charles G. Mullighan et al.   NATURE

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

The Transcription Factor PU.1 Controls Dendritic Cell Development and Flt3 Cytokine Receptor Expression in a Dose-Dependent Manner

(2010) Sebastian Carotta et al.   IMMUNITY

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

The Cell-Specific Induction of CXC Chemokine Ligand 9 Mediated by IFN-  in Microglia of the Central Nervous System Is Determined by the Myeloid Transcription Factor PU.1

(2010) S. L. Ellis et al.   JOURNAL OF IMMUNOLOGY

Regulation of Follicular B Cell Differentiation by the Related E26 Transformation-Specific Transcription Factors PU.1, Spi-B, and Spi-C

(2010) R. P. DeKoter et al.   JOURNAL OF IMMUNOLOGY

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

(2010) Hua-Chen Chang et al.   NATURE IMMUNOLOGY

Involvement of PU.1 in the transcriptional regulation of TNF-α

(2009) Tatsuo Fukai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Heterozygous deletion of the PU.1 locus in human AML

(2009) N. Bonadies et al.   BLOOD

A Recurrent Network Involving the Transcription Factors PU.1 and Gfi1 Orchestrates Innate and Adaptive Immune Cell Fates

(2009) Chauncey J. Spooner et al.   IMMUNITY

Cooperation between PU.1 and CAAT/Enhancer-binding Protein β Is Necessary to Induce the Expression of the MD-2 Gene

(2009) Pierre Tissières et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PU.1 and partners: regulation of haematopoietic stem cell fate in normal and malignant haematopoiesis

(2009) Pallavi Gupta et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Oncogene Addiction

(2008) I. B. Weinstein et al.   CANCER RESEARCH

PU.1 expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared cis-regulatory element

(2008) A. K. Ebralidze et al.   GENES & DEVELOPMENT

Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder

(2008) Ryan M. O'Connell et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity

(2008) M B Kamath et al.   LEUKEMIA