Article
Respiratory System
Fatma Esra Gunaydin, Dane Ediger, Muge Erbay
Summary: Fatigue is common in asthmatic patients and is associated with asthma-related quality of life, asthma control, dyspnea, depression, and anxiety. Future studies are needed to better understand the factors that precipitate or perpetuate fatigue in asthma.
CLINICAL RESPIRATORY JOURNAL
(2021)
Article
Pediatrics
Darshith Saragondlu Lakshminarasappa, Venkatesh Chandrasekaran, Preeti Kandasamy
Summary: The study revealed that co-morbid anxiety and depression are common in children with asthma, and are significantly associated with poor symptom control.
PEDIATRIC PULMONOLOGY
(2021)
Article
Pediatrics
Delaney Griffiths, Lauren M. Giancola, Kelly Welsh, Kristen MacGlashing, Christine Thayer, Sigfus Gunnlaugsson, Natalie P. Stamatiadis, Gabriella C. Sierra, Adam Hammond, Kimberly F. Greco, Tregony Simoneau, Sachin N. Baxi, Jonathan M. Gaffin
Summary: The study found that symptoms of anxiety and depression are common in children with severe asthma, and they negatively impact asthma symptom control in girls but not boys. Additionally, girls are more significantly affected by mental health issues than boys in the context of severe asthma.
PEDIATRIC PULMONOLOGY
(2021)
Article
Integrative & Complementary Medicine
Na Zhu, Fang Gu, Yiqian Hu, Wen Bian
Summary: The study found that stress psychological intervention in patients with acute respiratory failure can significantly improve cardiopulmonary function, reduce negative emotions, enhance self-efficacy, and improve quality of life.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE
(2021)
Review
Neurosciences
Kolsoum Dehdar, Mohammad Reza Raoufy
Summary: Psychiatric disorders are common in patients with allergic asthma, and recent studies suggest that immune-brain communication mechanisms may contribute to the alterations in brain structure and function that lead to anxiety in these patients. This paper comprehensively reviews the research on asthma-induced brain alterations and highlights the importance of addressing neuropsychiatric disorders in asthma clinical guidelines for improved patient quality of life. Understanding the mechanisms underlying psychiatric comorbidities in asthma could lead to more effective treatments.
BRAIN RESEARCH BULLETIN
(2023)
Article
Environmental Sciences
Sarah Koch, Joseph F. Welch, Raymond Tran, Andrew H. Ramsook, Andy Hung, Christopher Carlsten, Jordan A. Guenette, Michael S. Koehle
Summary: The study found that using salbutamol before moderate-intensity exercise in high levels of diesel exhaust did not reduce respiratory function or exercise ventilatory responses, with no significant changes observed up to 60 minutes following exercise.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Allergy
Mahdi Sheykhi, Ali Pourvali, Yazdan Ghandi, Anita Alaghmand, Maryam Zamanian, Tina Eslambeik, Amin Tajerian
Summary: This study highlights a significant association between asthma and heightened anxiety symptoms in children, particularly in domains such as separation anxiety, social phobia, agoraphobia, and fears related to physical injury. Children with asthma exhibited significantly higher anxiety symptoms compared to those without asthma. Furthermore, increased anxiety levels in pediatric asthma patients were associated with increased need for medication, frequency of nocturnal symptoms, and asthma severity.
Article
Medicine, Research & Experimental
Kolsoum Dehdar, Morteza Mooziri, Ali Samii Moghaddam, Morteza Salimi, Milad Nazari, Samaneh Dehghan, Hamidreza Jamaati, Alireza Salimi, Mohammad Reza Raoufy
Summary: This study evaluated lung and brain inflammation as well as anxiety in an animal model of allergic asthma pretreated with inhaled fluticasone propionate. The results showed that allergen induced anxiety and inflammation in the medial prefrontal cortex (mPFC) and amygdala, as well as disruptions in the local and long-range oscillatory activities within the mPFC-amygdala circuit. Pretreatment with inhaled fluticasone partially prevented these asthma-induced changes. The findings suggest that early treatment with inhaled corticosteroids can improve mPFC-amygdala circuit function and reduce anxiety by attenuating neuroinflammation.
Article
Respiratory System
Jennifer Steinmann, Adam Lewis, Toby J. Ellmers, Mandy Jones, Vicky MacBean, Elmar Kal
Summary: The Breathing Vigilance Questionnaire (Breathe-VQ) is a valid and reliable tool to measure breathing vigilance, which can determine the presence of dysfunctional breathing by examining its correlation with factors such as anxiety and autonomic dysfunction. High vigilance may contribute to breathing disorders and can be targeted in therapy.
EUROPEAN RESPIRATORY JOURNAL
(2023)
Article
Respiratory System
Angelos Vontetsianos, Damla Karadeniz Guven, Sophie Betka, Sara Souto-Miranda, Mathieu Marillier, Oliver J. Price, Chi Yan Hui, Pradeesh Sivapalan, Cristina Jacome, Andrea Aliverti, Georgios Kaltsakas, Shailesh B. Kolekar, Rachael A. Evans, Guido Vagheggini, Claudia Vicente, Vitalii Poberezhets, Sam Bayat, Hilary Pinnock, Frits M. E. Franssen, Ioannis Vogiatzis, Malek Chaabouni, Thomas Gille
Summary: This article provides an overview of the laboratory-based science, clinical trials, and qualitative research presented during the 2022 European Respiratory Society International Congress in the sessions from the five groups of Assembly 1. The selected presentations cover a wide range of topics including clinical problems, rehabilitation and chronic care, general practice and primary care, mobile/electronic health (m-health/e-health), clinical respiratory physiology, exercise, and functional imaging.
Review
Medicine, General & Internal
Annamaria Bosi, Roberto Tonelli, Ivana Castaniere, Enrico Clini, Bianca Beghe
Summary: Patients with acute asthma attack often present to the emergency room with severe functional impairment despite low symptom perception. Early functional assessment focusing on vital parameters, respiratory function, and perceived dyspnea is crucial. Treatment planning and patient education are equally important, significantly impacting long-term outcomes of asthma.
Article
Respiratory System
Michelle A. Stubbs, Vanessa L. Clark, Peter G. Gibson, Janelle Yorke, Vanessa M. McDonald
Summary: Anxiety and depression are common comorbidities in patients with severe asthma, and are associated with poorer quality of life and asthma control. Dyspnoea, dysfunctional breathing, and obesity are clinical characteristics associated with these symptoms in severe asthma.
RESPIRATORY RESEARCH
(2022)
Article
Multidisciplinary Sciences
Oscar W. H. Wong, Angela M. W. Lam, Brian P. N. Or, Flora Y. M. Mo, Caroline K. S. Shea, Kelly Y. C. Lai, Suk Ling Ma, Se Fong Hung, Sandra Chan, Thomas N. Y. Kwong, Sunny Wong, Patrick W. L. Leung
Summary: Emerging evidence suggests an altered gut microbiome in autism spectrum disorder (ASD) through the gut-brain axis, despite inconsistent findings. This study highlights the lack of exploration of the role of comorbid functional gastrointestinal disorder (FGID) in the association between ASD and altered gut microbiome. The study found a significant decrease in within-sample abundance of taxa in ASD compared to typically developing (TD) individuals, regardless of FGID status. The composition of the gut microbiome in ASD with FGID displayed differences from ASD without FGID, along with higher levels of anxiety and overall psychopathology. Further research is needed to understand how FGID may impact neuropsychiatric symptoms in ASD through inflammation along the microbiota-gut-brain axis.
SCIENTIFIC REPORTS
(2022)
Article
Allergy
Martin Bedolla-Barajas, Jaime Morales-Romero, Juan Carlos Fonseca-Lopez, Norma Angelica Pulido-Guillen, Desiree Larenas-Linnemann, Dante Daniel Hernandez-Colin
Summary: This study found that more than half of all asthmatic patients suffer from anxiety and depression. Depression increased the odds of anxiety in patients with asthma, while well-controlled asthma and allergic sensitization decreased the likelihood of anxiety. Additionally, depression was associated with both obesity and anxiety.
Article
Immunology
Ruihua Hou, Gang Ye, Xiaojing Cheng, Dominick E. Shaw, Per S. Bakke, Massimo Caruso, Barbro Dahlen, Sven-Erik Dahlen, Stephen J. Fowler, Ildiko Horvath, Peter Howarth, Norbert Krug, Paolo Montuschi, Marek Sanak, Thomas Sandstrom, Charles Auffray, Bertrand De Meulder, Ana R. Sousa, Ian M. Adcock, Kian Fan Chung, Peter J. Sterk, Paul J. Skipp, James Schofield, Ratko Djukanovic
Summary: This study investigated the role of inflammation in comorbid anxiety and depression in asthma patients and found that severe asthma patients have higher levels of anxiety and depression, which may be associated with inflammatory responses.
BRAIN BEHAVIOR AND IMMUNITY
(2023)