Review
Microbiology
Jiantao Yu, Qiucheng Yao, Jing Liu, Yan Zhou, Miaotong Huo, Ye Ge
Summary: The H3-subtype of avian influenza virus is a common low pathogenic subtype in birds and fowls, causing economic loss to the poultry industry and posing a threat to public health. However, there is inadequate monitoring and lack of effective prevention and control measures for this subtype.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Zhihao Sun, Qiuxia Wang, Gang Li, Jingzhi Li, Sujuan Chen, Tao Qin, Hongwei Ma, Daxin Peng, Xiufan Liu
Summary: The study successfully identified a specific epitope H7-12 peptide for H7N9 AIV and evaluated the protection and serological DIVA characteristics of the recombinant H7N9 AIV strain. The recombinant H7N9 AIV strain JD-cHA/17 showed good protection against H7N9 AIV challenge and could be detected using a specific peptide chip for DIVA testing.
MICROBIOLOGY SPECTRUM
(2021)
Review
Microbiology
Saba Rafique, Farooq Rashid, Sajda Mushtaq, Akbar Ali, Meng Li, Sisi Luo, Liji Xie, Zhixun Xie
Summary: The highly pathogenic avian influenza (HPAI) subtype H5N8, originated from wild birds in China, poses a significant threat to poultry and human health. It has caused severe crises in the poultry meat industry worldwide and continuous monitoring and strict biosecurity measures are needed to reduce the risk of virus transmission.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Genetics & Heredity
Fatin Ahmad Rizal, Kok Lian Ho, Abdul Rahman Omar, Wen Siang Tan, Abdul Razak Mariatulqabtiah, Munir Iqbal
Summary: This study compared the molecular markers of a locally isolated LPAI AIV strain H5N2 from Malaysia with reference HPAI strains, revealing distinct characteristics of the Malaysian strain and its potential role in the epidemiological research on circulating AIV in poultry.
Article
Virology
Wanhong Xu, Roberto Navarro-Lopez, Mario Solis-Hernandez, Francisco Liljehult-Fuentes, Miguel Molina-Montiel, Maria Lagunas-Ayala, Marisol Rocha-Martinez, Eduardo Ferrara-Tijera, Juan Perez de la Rosa, Yohannes Berhane
Summary: This study presents a comprehensive evolutionary analysis of the Mexican lineage H5N2 avian influenza virus, revealing its origin from the North American wild bird gene pool and current circulation in poultry populations of Mexico, the Dominican Republic, and Taiwan. The highly pathogenic H5N2 virus was eradicated from Mexican poultry in 1995, but the low pathogenic H5N2 virus continued to circulate and evolve into five distinct clades. The study highlights the importance of vaccine updates and continued molecular monitoring of the HA protein for antigenic changes.
Review
Virology
Mingqin Lin, Qiu-Cheng Yao, Jing Liu, Miaotong Huo, Yan Zhou, Minyi Chen, Yuanguo Li, Yuwei Gao, Ye Ge
Summary: The H6 subtype of avian influenza virus is the most commonly detected subtype in poultry and wild birds. It causes economic losses to the poultry industry and poses a great threat to public health security as it has the potential to infect mammals. Furthermore, the H6 subtype can serve as a precursor for other highly pathogenic avian influenza viruses, presenting a potential threat. This study focused on the prevalence, genetic variation, and prevention and control of H6 AIV to provide references for future scientific prevention and control measures.
Article
Microbiology
Pei Zhou, Bo Chen, Xinkai Hu, Xiangyu Xiao, Ruohan Liu, Shoujun Li
Summary: The study evaluated the transmissibility of the first- and last-isolated Chinese H3N2 CIV strains to birds, and the results demonstrated that avian species are unsusceptible to H3N2 CIV, indicating unidirectional evolution of the mammalian host tropism of H3N2 CIV.
VETERINARY MICROBIOLOGY
(2022)
Article
Microbiology
Yoshikazu Fujimoto, Kohei Ogasawara, Norikazu Isoda, Hitoshi Hatai, Kosuke Okuya, Yukiko Watanabe, Ayato Takada, Yoshihiro Sakoda, Keisuke Saito, Makoto Ozawa
Summary: This study demonstrates the susceptibility of white-tailed sea eagles to H5 HPAI virus and confirms the potential for indirect transmission within the population. Histopathological observations suggest that viral replication in the brain is responsible for the severity and mortality of the disease in this species.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Infectious Diseases
Sungsu Youk, Christina M. Leyson, Darren J. Parris, Henry M. Kariithi, David L. Suarez, Mary J. Pantin-Jackwood
Summary: Mexican lineage H5N2 avian influenza viruses have evolved from low pathogenicity to highly pathogenicity and spread to multiple countries. Genetic reassortment and mechanical transmission are important factors in the virus's spread and evolution. There are differences in infectivity and transmission between chicken and mallard, and genetic changes may affect vaccine efficacy.
TRANSBOUNDARY AND EMERGING DISEASES
(2022)
Article
Immunology
Varsha Potdar, Megha Brijwal, Rakesh Lodha, Pragya Yadav, Santosh Jadhav, Manohar Lal Choudhary, Aashish Choudhary, Veena Vipat, Nivedita Gupta, Ashok Kumar Deorari, Lalit Dar, Priya Abraham
Summary: An 11-year-old boy with acute myeloid leukemia in New Delhi, India, was treated for severe acute respiratory infection caused by avian influenza A(H5N1). The strain belonged to hemagglutinin gene clade 2.3.2.1a and was found to be susceptible to amantadine and neuraminidase inhibitors.
EMERGING INFECTIOUS DISEASES
(2022)
Article
Infectious Diseases
Zhichuang Ge, Lijun Xu, Xiaomiao Hu, Shanshan Zhu, Ying Zhao, Yang Li, Kaituo Liu, Ruyi Gao, Xiaoquan Wang, Jiao Hu, Xiaowen Liu, Shunlin Hu, Daxin Peng, Min Gu, Xiufan Liu
Summary: The co-circulation of H5 HPAI and H9N2 LPAI viruses has led to the emergence of novel reassortant H5NX viruses. Two novel H5N2 HPAI isolates were identified with HA genes from clade 2.3.2.1e of H5N1 viruses and other gene segments from endemic H9N2 viruses. The isolates showed differences in amino acid substitutions in polymerase genes and exhibited distinct effects on chickens and mice.
INFECTION GENETICS AND EVOLUTION
(2022)
Article
Virology
Sung-Su Youk, Christina M. Leyson, Brittany A. Seibert, Samadhan Jadhao, Daniel R. Perez, David L. Suarez, Mary J. Pantin-Jackwood
Summary: The study reveals that the H5N2 avian influenza virus adapted to poultry hosts through genetic changes, enhancing infectivity and pathogenicity. This provides important insights into the epidemiology and adaptation of H5Nx HPAI viruses in poultry.
JOURNAL OF VIROLOGY
(2021)
Article
Virology
Swan Tan, Muhammad Farhan Sjaugi, Siew Chinn Fong, Li Chuin Chong, Hadia Syahirah Abd Raman, Nik Elena Nik Mohamed, Joseph Thomas August, Asif M. Khan
Summary: Avian influenza virus H7N9, which has been circulating in avian hosts for decades, was identified as a human pathogen in 2013. Through comparing sequences from avian and human H7N9 datasets, it was found that the virus has undergone significant amino acid substitutions possibly essential for human adaptation. The rapid evolution of the avian H7N9 virus has resulted in almost identical protein sequences in avian and human viruses, leading to increased risk of human infection and potential human-to-human transmission.
Letter
Immunology
Samnang Um, Jurre Y. Siegers, Borann Sar, Savuth Chin, Sarika Patel, Seng Bunnary, Makara Hak, Sothy Sor, Oum Sokhen, Seng Heng, Darapheak Chau, Tum Sothyra, Asheena Khalakdina, Joshua A. Mott, Sonja J. Olsen, Filip Claes, Ly Sovann, Erik A. Karlsson
Summary: In February 2021, a case of human avian influenza A(H9N2) virus infection was detected in Cambodia through routine surveillance. Investigations found no recent H9N2 virus infections among 43 close contacts. A chicken sample from the infected child's house tested positive for H9N2 virus and was genetically similar to the human virus.
EMERGING INFECTIOUS DISEASES
(2021)
Article
Veterinary Sciences
Farahnaz Motamedi Sedeh, Iraj Khalili, Viskam Wijewardana, Hermann Unger, Parvin Shawrang, Mehdi Behgar, Sayed Morteza Moosavi, Arash Arbabi, Sayedeh Maede Hosseini
Summary: Gamma radiation can enhance immunity compared to formalin inactivation in vaccinating broiler chickens with low-pathogenic avian influenza virus-H9N2. The IVT.IN vaccination regime showed more significant antibody titration and spleen lymphocyte proliferation in the late regime. Cytokine levels were upregulated more noticeably in the late vaccination regime.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Virology
Yoshinao Yamazaki, M. Doy, S. Yamato, Y. Kawada, T. Ogata
ARCHIVES OF VIROLOGY
(2008)
Article
Public, Environmental & Occupational Health
Tsuyoshi Ogata, Yoshinao Yamazaki, Nobuhiko Okabe, Yosikazu Nakamura, Masato Tashiro, Noriko Nagata, Shigeyuki Itamura, Yoshinori Yasui, Kazutoshi Nakashima, Mikio Doi, Youko Izumi, Takashi Fujieda, Shin'ichi Yamato, Yuichi Kawada
JOURNAL OF EPIDEMIOLOGY
(2008)
Article
Environmental Sciences
Tsuyoshi Ogata, Natsuki Nagasu, Ritei Uehara, Kunihiko Ito
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2019)
Article
Environmental Sciences
Tsuyoshi Ogata, Hideo Tanaka
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2020)
Article
Infectious Diseases
Tsuyoshi Ogata, Maki Murooka, Makoto Akashi, Akemi Ishitsuka, Akari Miyazaki, Shuuichi Osawa, Kanako Ishikawa, Keiko Tanaka-Taya, Ritei Uehara
Summary: The study found that the period from the onset of fever to the onset of rash was usually limited to -1 day to 2 days among confirmed rubella patients. If the period from fever to rash onset was >= 3 days for a patient, the likelihood of rubella was low.
BMC INFECTIOUS DISEASES
(2021)
Article
Environmental Sciences
Tsuyoshi Ogata, Hideo Tanaka
Summary: Long diagnostic delays in COVID-19 patients with unknown exposure are inversely correlated with the subsequent doubling time.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Hideo Tanaka, Atsushi Hirayama, Hitomi Nagai, Chika Shirai, Yuki Takahashi, Hiroto Shinomiya, Chie Taniguchi, Tsuyoshi Ogata
Summary: A study in Japan revealed that the SARS-CoV-2 Alpha variant has a transmission capability approximately 1.9-2.3 times higher than the pre-existing virus, resulting in a significantly increased secondary attack rate in household contacts.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Tsuyoshi Ogata, Fujiko Irie, Eiko Ogawa, Shifuko Ujiie, Aina Seki, Koji Wada, Hideo Tanaka
Summary: Household secondary attack rate (HSAR) may have a higher transmission rate between spouses, while smaller household size can lower the HSAR among non-spousal contacts of COVID-19 patients. Non-spousal household contacts of index patients with longer diagnostic delay tend to have higher HSAR.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Tsuyoshi Ogata, Hideo Tanaka, Fujiko Irie, Atsushi Hirayama, Yuki Takahashi
Summary: This study aimed to compare the transmission dynamics, particularly the incubation period, of the SARS-CoV-2 Delta variant with non-Delta strains. The findings revealed that unvaccinated Delta variant cases had shorter incubation periods than non-Delta variant cases.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Tsuyoshi Ogata, Hideo Tanaka, Yumiko Nozawa, Kazue Mukouyama, Emiko Tanaka, Natsumi Osaki, Etsuko Noguchi, Kayoko Seo, Koji Wada
Summary: This study aimed to compare the household secondary attack rate (HSAR) of the Delta variant with the Alpha variant and evaluate risk factors among unvaccinated household contacts. The results showed that the HSAR was higher for household contacts of Delta variant index cases compared to Alpha variant index cases. Within the Delta variant, spouses of index cases had a higher HSAR, while household contacts aged <= 19 had a lower HSAR.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Tsuyoshi Ogata, Hideo Tanaka, Emiko Tanaka, Natsumi Osaki, Etsuko Noguchi, Yukino Osaki, Ayane Tono, Koji Wada
Summary: This study investigated the household secondary attack rate of patients with COVID-19 during the omicron variant-dominant period and found that vaccination of index patients may protect household contacts. The results showed that during the omicron variant-dominant period, the HSAR among household contacts was significantly higher than that during the delta variant-dominant period.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Environmental Sciences
Hideo Tanaka, Tsuyoshi Ogata, Toshiyuki Shibata, Hitomi Nagai, Yuki Takahashi, Masaru Kinoshita, Keisuke Matsubayashi, Sanae Hattori, Chie Taniguchi
Summary: This study aimed to compare the incubation period between patients infected with the SARS-CoV-2 Omicron variant and the Alpha variant. The results showed that the incubation period of the Omicron variant, especially the sublineage BA.1, was significantly shorter than that of the Alpha variant, which may partially explain the variant replacement observed in many countries from late 2021 to early 2022.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Immunology
Tsuyoshi Ogata, Hideo Tanaka
Summary: The mean virus incubation period during the SARS-CoV-2 Omicron BA.5-dominant period in Japan was 2.6 (95% CI 2.5-2.8) days, which was less than during the Delta-dominant period. Incubation period correlated with shared meals and adult infectors. A shorter incubation suggests a shorter quarantine period for BA.5 than for other variants.
EMERGING INFECTIOUS DISEASES
(2023)
Article
Public, Environmental & Occupational Health
Tsuyoshi Ogata, Hideo Tanaka, Fujiko Irie, Yumiko Nozawa, Etsuko Noguchi, Kayoko Seo, Emiko Tanaka
Summary: A study found that the proportion of asymptomatic COVID-19 patients infected with the L452R mutation strain from June to September 2021 was lower compared to those infected with the wild-type strain from November 2020 to January 2021. This may contribute to the attenuation of transmission.
GLOBAL HEALTH & MEDICINE
(2022)
