Efficacy of the rePON1 mutant IIG1 to prevent cyclosarin toxicity in vivo and to detoxify structurally different nerve agents in vitro

The value of novel oximes for treatment of poisoning by organophosphorus compounds

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Identification and characterization of novel catalytic bioscavengers of organophosphorus nerve agents

(2012) Tamara C. Otto et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Human plasma-derived BuChE as a stoichiometric bioscavenger for treatment of nerve agent poisoning

(2012) Helen Mumford et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Human paraoxonase double mutants hydrolyze V and G class organophosphorus nerve agents

(2012) Stephen D. Kirby et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Evolved Stereoselective Hydrolases for Broad-Spectrum G-Type Nerve Agent Detoxification

(2012) Moshe Goldsmith et al.   CHEMISTRY & BIOLOGY

Directed evolution of hydrolases for prevention of G-type nerve agent intoxication

(2011) Rinkoo D Gupta et al.   Nature Chemical Biology

Post-exposure therapy with recombinant human BuChE following percutaneous VX challenge in guinea-pigs

(2011) Helen Mumford et al.   TOXICOLOGY LETTERS

In search of a catalytic bioscavenger for the prophylaxis of nerve agent toxicity

(2010) Robert C. diTargiani et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Chromatographic preparation and kinetic analysis of interactions between tabun enantiomers and acetylcholinesterase

(2010) O. Tenberken et al.   TOXICOLOGY LETTERS

The oxime pro-2-PAM provides minimal protection against the CNS effects of the nerve agents sarin, cyclosarin, and VX in guinea pigs

(2010) Tsung-Ming Shih et al.   TOXICOLOGY MECHANISMS AND METHODS

Evaluation of nine oximes on in vivo reactivation of blood, brain, and tissue cholinesterase activity inhibited by organophosphorus nerve agents at lethal dose

(2009) Tsung-Ming Shih et al.   TOXICOLOGY MECHANISMS AND METHODS

Chromatographic resolution, characterisation and quantification of VX enantiomers in hemolysed swine blood samples

(2008) Georg Reiter et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES