Role of autophagy in methylmercury-induced neurotoxicity in rat primary astrocytes

p62/SQSTM1 at the interface of aging, autophagy, and disease

(2014) Alessandro Bitto et al.   AGE

Is mitochondrial generation of reactive oxygen species a trigger for autophagy?

(2014) Yongqiang Chen et al.   Autophagy

p62 provides dual cytoprotection against oxidative stress in the retinal pigment epithelium

(2014) Lei Wang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Exploring Cross-Talk Between Oxidative Damage and Excitotoxicity and the Effects of Riluzole in the Rat Cortex After Exposure to Methylmercury

(2014) Yu Deng et al.   NEUROTOXICITY RESEARCH

Heavy metal scavenger metallothionein attenuates ER stress-induced myocardial contractile anomalies: Role of autophagy

(2014) Lifang Yang et al.   TOXICOLOGY LETTERS

Synthesis and screening of 3-MA derivatives for autophagy inhibitors

(2013) Yanyang Wu et al.   Autophagy

Induction of cytoprotective autophagy in PC-12 cells by cadmium

(2013) Qiwen Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interplay between autophagy and apoptosis mediated by copper oxide nanoparticles in human breast cancer cells MCF7

(2013) Dipranjan Laha et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Regulation of HA14-1 mediated oxidative stress, toxic response, and autophagy by curcumin to enhance apoptotic activity in human embryonic kidney cells

(2013) Kishu Ranjan et al.   BIOFACTORS

Evodiamine, a plant alkaloid, induces calcium/JNK-mediated autophagy and calcium/mitochondria-mediated apoptosis in human glioblastoma cells

(2013) Ann-Jeng Liu et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Autophagy and inflammatory diseases

(2013) Sarah A Jones et al.   IMMUNOLOGY AND CELL BIOLOGY

Methylmercury induces caspase-dependent apoptosis and autophagy in human neural stem cells

(2013) Seung-Hee Chang et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Autophagy is involved in the effects of resveratrol on prevention of splenocyte apoptosis caused by oxidative stress in restrained mice

(2013) Wen-Jun Duan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Protective Effects of Memantine Against Methylmercury-Induced Glutamate Dyshomeostasis and Oxidative Stress in Rat Cerebral Cortex

(2013) Wei Liu et al.   NEUROTOXICITY RESEARCH

Autophagy Adaptor Protein p62/SQSTM1 and Autophagy-Related Gene Atg5 Mediate Autophagosome Formation in Response to Mycobacterium tuberculosis Infection in Dendritic Cells

(2013) Shintaro Seto et al.   PLoS One

Impairment of autophagy: From hereditary disorder to drug intoxication

(2013) Toshihiko Aki et al.   TOXICOLOGY

Autophagy protein p62/SQSTM1 is involved in HAMLET-induced cell death by modulating apotosis in U87MG cells

(2013) Y-B Zhang et al.   Cell Death & Disease

Regulation of autophagy in rat hepatocytes treatedin vitrowith low concentration of mercury

(2013) Sarmishtha Chatterjee et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

Rotenone Inhibits Autophagic Flux Prior to Inducing Cell Death

(2012) Burton J. Mader et al.   ACS Chemical Neuroscience

Autophagy in Toxicology: Cause or Consequence?

(2012) Sten Orrenius et al.   Annual Review of Pharmacology and Toxicology

The end of autophagic cell death?

(2012) Shensi Shen et al.   Autophagy

Excitotoxicity and oxidative damages induced by methylmercury in rat cerebral cortex and the protective effects of tea polyphenols

(2012) Wei Liu et al.   ENVIRONMENTAL TOXICOLOGY

Adaptive Response, Evidence of Cross-Resistance and Its Potential Clinical Use

(2012) Irina Milisav et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Glia and Methylmercury Neurotoxicity

(2012) Mingwei Ni et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Considerations on methylmercury (MeHg) treatments in in vitro studies

(2012) Michael Aschner   NEUROTOXICOLOGY

The autophagy-associated factors DRAM1 and p62 regulate cell migration and invasion in glioblastoma stem cells

(2012) S Galavotti et al.   ONCOGENE

Autophagy Activation: A Novel Mechanism of Atorvastatin to Protect Mesenchymal Stem Cells from Hypoxia and Serum Deprivation via AMP-Activated Protein Kinase/Mammalian Target of Rapamycin Pathway

(2012) Qian Zhang et al.   STEM CELLS AND DEVELOPMENT

Low concentration of mercury induces autophagic cell death in rat hepatocytes

(2012) Sarmishtha Chatterjee et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Mechanisms of methylmercury-induced neurotoxicity: Evidence from experimental studies

(2011) Marcelo Farina et al.   LIFE SCIENCES

Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen

(2011) Zhaobao Yin et al.   NEUROTOXICOLOGY

Protective effect of a novel peptide against methylmercury-induced toxicity in rat primary astrocytes

(2011) Uri Wormser et al.   NEUROTOXICOLOGY

Assessment of mercury and selenium concentrations in captive bottlenose dolphin's (Tursiops truncatus) diet fish, blood, and tissue

(2011) Yong Seok Hong et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cadmium-Induced Autophagy in Rat Kidney: An Early Biomarker of Subtoxic Exposure

(2011) Abderrahman Chargui et al.   TOXICOLOGICAL SCIENCES

Cadmium induces autophagy through ROS-dependent activation of the LKB1–AMPK signaling in skin epidermal cells

(2011) Young-Ok Son et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Oxidative stress in MeHg-induced neurotoxicity

(2011) Marcelo Farina et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

AMPK- and p62/SQSTM1-dependent autophagy mediate Resveratrol-induced cell death in chronic myelogenous leukemia

(2010) Alexandre Puissant et al.   Autophagy

A reporter cell system to monitor autophagy based on p62/SQSTM1

(2010) Kenneth Bowitz Larsen et al.   Autophagy

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK-mediated autophagy inhibits apoptosis in cisplatin-treated tumour cells

(2010) L. Harhaji-Trajkovic et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lithium rescues the impaired autophagy process in CbCln3Δex7/8/Δex7/8 cerebellar cells and reduces neuronal vulnerability to cell death via IMPase inhibition

(2010) Jae-Woong Chang et al.   JOURNAL OF NEUROCHEMISTRY

Review: Autophagy and neurodegeneration: survival at a cost?

(2010) S. J. Cherra III et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Hippocampal Neurons Exposed to the Environmental Contaminants Methylmercury and Polychlorinated Biphenyls Undergo Cell Death via Parallel Activation of Calpains and Lysosomal Proteases

(2010) Roshan Tofighi et al.   NEUROTOXICITY RESEARCH

Oxidative Stress and Autophagy in Cardiac Disease, Neurological Disorders, Aging and Cancer

(2010) Eric E. Essick et al.   Oxidative Medicine and Cellular Longevity

Comparative study of quercetin and its two glycoside derivatives quercitrin and rutin against methylmercury (MeHg)-induced ROS production in rat brain slices

(2009) Caroline Wagner et al.   ARCHIVES OF TOXICOLOGY

Rapamycin inhibits mTORC1, but not completely

(2009) Carson C. Thoreen et al.   Autophagy

ROS-mediated autophagy was involved in cancer cell death induced by novel copper(II) complex

(2009) Wen-jie Guo et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Review: Autophagy in neurodegeneration: firefighter and/or incendiarist?

(2009) A. Rami   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Cadmium Toxicity toward Autophagy through ROS-Activated GSK-3β in Mesangial Cells

(2009) Sheng-Hao Wang et al.   TOXICOLOGICAL SCIENCES

Characterization of demethylation of methylmercury in cultured astrocytes

(2008) Aaron M. Shapiro et al.   CHEMOSPHERE

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Promotion of autophagy and inhibition of apoptosis by low concentrations of cadmium in vascular endothelial cells

(2008) Zhiwu Dong et al.   TOXICOLOGY IN VITRO

Mecamylamine prevents neuronal apoptosis induced by glutamate and low potassium via differential anticholinergic-independent mechanisms

(2007) Hongjun Fu et al.   NEUROPHARMACOLOGY