Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods

Title
Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods
Authors
Keywords
UN GHS/EU CLP, Drivers of classification, Eye irritation/serious eye damage, Draize within-test variability, Validation of in vitro methods
Journal
ARCHIVES OF TOXICOLOGY
Volume 88, Issue 3, Pages 701-723
Publisher
Springer Nature
Online
2013-12-27
DOI
10.1007/s00204-013-1156-8

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