Article
Clinical Neurology
T. Huckhagel, C. Riedel, V. Rohde, R. Lefering
Summary: Traumatic brain injury (TBI) is a major cause of disability and mortality. This study aimed to determine the incidence of cranial nerve injuries (CNI) in TBI patients and compare the differences between TBI cases with and without CNI. The results showed that CNI rarely occur in TBI patients, but when present, they are associated with an increased risk of functional impairment and complications such as skull base fractures.
CLINICAL NEUROLOGY AND NEUROSURGERY
(2022)
Article
Rehabilitation
Noah D. Silverberg, Grant L. Iverson, Alison Cogan, Kristen Dams-O-Connor, Richard Delmonico, Min Jeong P. Graf, Mary Alexis Iaccarino, Maria Kajankova, Joshua Kamins, Karen L. McCulloch, Gary McKinney, Drew Nagele, William J. Panenka, Amanda R. Rabinowitz, Nick Reed, Jennifer Wethe, Victoria Whitehair, Vicki Anderson, David B. Arciniegas, Mark T. Bayley, Jeffery J. Bazarian, Kathleen R. Bell, Steven P. Broglio, David Cifu, Gavin A. Davis, Jiri Dvorak, Ruben J. Echemendia, Gerard A. Gioia, Christopher C. Giza, Sidney R. Hinds II, Douglas I. Katz, Brad G. Kurowski, John J. Leddy, Natalie Le Sage, Angela Lumba-Brown, Andrew I. R. Maas, Geoffrey T. Manley, Michael McCrea, David K. Menon, Jennie Ponsford, Margot Putukian, Stacy J. Suskauer, Joukje van der Naalt, William C. Walker, Keith Owen Yeates, Ross Zafonte, Nathan D. Zasler, Roger Zemek
Summary: This study aims to develop new diagnostic criteria for mild traumatic brain injury (TBI) that are appropriate for use across the lifespan and in sports, civilian trauma, and military settings. Through a rapid evidence review and Delphi method, a 90.7% agreement on the diagnostic criteria was reached, which will improve the quality and consistency of mild TBI research and clinical care.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Rehabilitation
Dawn Neumann, Shannon B. Juengst, Charles H. Bombardier, Jacob A. Finn, Shannon R. Miles, Yue Zhang, Richard Kennedy, Amanda R. Rabinowitz, Amber Thomas, Laura E. Dreer
Summary: This study aimed to determine anxiety trajectories and predictors up to 10 years after traumatic brain injury (TBI). The results showed that factors such as race, insurance, pre-injury mental health treatment, multiple TBIs with loss of consciousness, violent injury, and years post-TBI were associated with higher levels of anxiety. Three different anxiety trajectories were identified, with the high-increasing and high-decreasing groups having consistently mild or higher anxiety scores throughout the 10-year period.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Medicine, General & Internal
Alicja Widuch-Spodyniuk, Beata Tarnacka, Bogumil Korczynski, Justyna Wisniowska
Summary: Innovative rehabilitation methods, such as robotic-assisted gait therapy (RAGT), have shown positive effects on the improvement of depression and anxiety symptoms in patients with spinal cord injuries (SCIs).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Rehabilitation
Jai Carmichael, Amelia J. Hicks, Kate Rachel Gould, Jennie Ponsford, Gershon Spitz
Summary: Objective of this study was to characterize trajectories of emotional distress across the first decade after moderate-severe traumatic brain injury (TBI) and explore relations with personal and injury-related factors. Results revealed that emotional distress is dynamic, heterogeneous, and often chronic during the first decade post-TBI, underscoring the need for ongoing monitoring and responsive treatment.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Public, Environmental & Occupational Health
Joseph Maffly-Kipp, Nikolett Eisenbeck, David F. Carreno, Joshua Hicks
Summary: This study found that mental health disparities are greater in countries with more severe COVID-19 outbreaks, with subjective SES, gender, and age as contributing factors. These findings are crucial for understanding the global impact of the ongoing pandemic and its implications for collective trauma.
SOCIAL SCIENCE & MEDICINE
(2021)
Article
Critical Care Medicine
Laura M. Heath, M. Rafae Kidwai, Brenda Colella, Georges Monette, Pavel Tselichtchev, Jennifer C. Tomaszczyk, Robin E. Green
Summary: This study examined the long-term trajectories of anxiety and depressive symptoms following moderate-severe traumatic brain injury (TBI), identified predictors of these trajectories, and explored their impact on 1-year return to productivity. The findings showed that there were four distinct trajectories for anxiety and depression, with most individuals experiencing stable or low levels over time. However, a subset of individuals showed rapid worsening of anxiety or depression, and those with worsening symptoms were less likely to return to productivity by 1-year post-injury.
JOURNAL OF NEUROTRAUMA
(2023)
Article
Anesthesiology
Iscander M. Maissan, Rutger Hollestelle, Koen Rijs, Selma Jaspers, Sanne Hoeks, Iain K. Haitsma, Dennis den Hartog, Robert J. Stolker
Summary: Advanced airway management can save lives among patients with traumatic brain injury by preventing hypoxia and hypercapnia. This study found that intravenous lidocaine attenuated the intracranial pressure (ICP) response to endotracheal intubation (ETI) during anesthesia induction. Therefore, adding lidocaine to the standard anesthesia medication may reduce the ICP response to ETI.
MINERVA ANESTESIOLOGICA
(2023)
Article
Psychology, Clinical
Jutta Joormann, Samuel A. McLean, Francesca L. Beaudoin, Xinming An, Jennifer S. Stevens, Donglin Zeng, Thomas C. Neylan, Gari Clifford, Sarah D. Linnstaedt, Laura T. Germine, Scott L. Rauch, Paul Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Gregory Fermann, Lauren A. Hudak, Kamran Mohiuddin, Vishnu Murty, Meghan E. McGrath, John P. Haran, Jose Pascual, Mark Seamon, David A. Peak, Claire Pearson, Robert M. Domeier, Paulina Sergot, Roland Merchant, Leon D. Sanchez, Niels K. Rathlev, William F. Peacock, Steven E. Bruce, Deanna Barch, Diego A. Pizzagalli, Beatriz Luna, Steven E. Harte, Irving Hwang, Sue Lee, Nancy Sampson, Karestan C. Koenen, Kerry J. Ressler, Ronald C. Kessler
Summary: This is the first report on the association between trauma exposure and depression. The study found that the characteristics of motor vehicle collision (MVC) and peritraumatic symptoms are associated with 8-week depression, while peritraumatic symptoms are associated with 2-week depression. The findings suggest the possibility of diverse and complex underlying biological and psychological processes.
PSYCHOLOGICAL MEDICINE
(2022)
Article
Rehabilitation
Tijn van Diemen, Yvonne Tran, Janneke M. Stolwijk-Swuste, Ellen H. Roels, SELF-SC Group, Ilse J. W. van Nes, Marcel W. M. Post
Summary: The study identified distinct trajectories of SE, depressive mood, and anxiety in SCI patients, and confirmed the interrelationships between them. Patients with high SE scores tended to adjust well with lower depressive mood and anxiety, while those with high depressive mood and anxiety scores were not always identifiable based on their SE trajectory.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Sheryl Katta-Charles, Leah M. Adams, Nancy D. Chiaravalloti, Flora M. Hammond, Paul B. Perrin, Amanda R. Rabinowitz, Umesh M. Venkatesan, Alan H. Weintraub, Charles H. Bombardier
Summary: The study aimed to investigate the prevalence, severity, and correlates of depression, anxiety, and suicidal ideation in individuals with traumatic brain injury (TBI) before and during the COVID-19 pandemic. The findings showed no significant differences in depression, anxiety, or suicidal ideation before vs during the pandemic, and the predictors of mental health outcomes remained similar. The results suggest a general resilience and are consistent with recent studies in the general population, indicating only temporary increases in psychological distress associated with the pandemic. Although not worsened, depression, anxiety, and suicidal ideation are still prevalent and require focused treatment and research efforts.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Clinical Neurology
Alvaro Rea-Neto, Elizeu Daniel da Silva, Gabriela Hassler, Valkiria Backes dos Santos, Rafaella Stradiotto Bernardelli, Amanda Christina Kozesinski-Nakatani, Marcelo Jose Martins-Junior, Fernanda Baeumle Reese, Mariana Bruinje Cosentino, Mirella Cristine Oliveira, Helio Afonso Ghizoni Teive
Summary: This retrospective cohort study analyzed data from patients with traumatic brain injury (TBI) admitted to an ICU in a Brazilian trauma referral hospital. The study found that patients with TBI had worse outcomes in terms of mortality compared to other trauma patients.
Review
Neurosciences
Lewis Murray
Summary: Nail gun injuries, especially intentional self-inflicted injuries, are a common form of craniocerebral injury with a mortality rate of around 10% and a low rate of residual neurological deficits. However, there is still a lack of sufficient data for clinical prognostication about long-term neurological impairments and recovery time.
Article
Cardiac & Cardiovascular Systems
Adrian Wells, David Reeves, Lora Capobianco, Calvin Heal, Linda Davies, Anthony Heagerty, Patrick Doherty, Peter Fisher
Summary: The study demonstrated that adding group metacognitive therapy significantly improved anxiety and depression symptoms in cardiac rehabilitation patients, and these effects remained significant at 12 months follow-up.
Review
Pharmacology & Pharmacy
C. Batson, A. Gomez, A. S. Sainbhi, L. Froese, F. A. Zeiler
Summary: This review article summarizes the impact of age and biological sex on outcomes of moderate/severe TBI patients through high-frequency multi-modal monitoring. By reviewing a large body of literature, it discusses the relationship between various physiological parameters and patient age and sex, while also identifying current knowledge gaps in the field.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Clinical Neurology
S. Soman, Z. Liu, G. Kim, U. Nemec, S. J. Holdsworth, K. Main, B. Lee, S. Kolakowsky-Hayner, M. Selim, A. J. Furst, P. Massaband, J. Yesavage, M. M. Adamson, P. Spincemallie, M. Moseley, Y. Wang
AMERICAN JOURNAL OF NEURORADIOLOGY
(2018)
Article
Clinical Neurology
Anthony H. Lequerica, Amanda Botticello, John O'Neill, Jean Lengenfelder, Denise Krch, Nancy D. Chiaravalloti, Angelle M. Sander, Tamara Bushnik, Jessica M. Ketchum, Flora M. Hammond, Kristen Dams-O'Connor, Elizabeth Felix, Doug Johnson-Greene
JOURNAL OF HEAD TRAUMA REHABILITATION
(2019)
Article
Rehabilitation
Allen W. Heinemann, Pamela A. Kisala, Aaron J. Boulton, Mark Sherer, Angelle M. Sander, Nancy Chiaravalloti, Tamara Bushnik, Robin Hanks, Elliot Roth, David S. Tulsky
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2020)
Article
Rehabilitation
Noelle E. Carlozzi, Pamela A. Kisala, Aaron J. Boulton, Elliot Roth, Anna L. Kratz, Mark Sherer, Angelle M. Sander, Allen W. Heinemann, Nancy D. Chiaravalloti, Tamara Bushnik, David S. Tulsky
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2020)
Article
Neurosciences
Anthony H. Lequerica, Erica Weber, Marcel P. Dijkers, Kristen Dams-O'Connor, Stephanie A. Kolakowsky-Hayner, Kathleen R. Bell, Tamara Bushnik, Yelena Goldan, Flora M. Hammond
Article
Public, Environmental & Occupational Health
Claire Z. Kalpakjian, Jodi M. Kreschmer, Mary D. Slavin, Pamela A. Kisala, Elisabeth H. Quint, Nancy D. Chiaravalloti, Natalie Jenkins, Tamara Bushnik, Dagmar Amtmann, David S. Tulsky, Roxanne Madrid, Rebecca Parten, Michael Evitts, Carolyn L. Grawi
JOURNAL OF WOMENS HEALTH
(2020)
Article
Clinical Neurology
Angelle M. Sander, Jessica M. Ketchum, Anthony H. Lequerica, Monique R. Pappadis, Tamara Bushnik, Flora M. Hammond, Mitch Sevigny
Summary: The study found that English-speaking Hispanic participants with complicated mild to severe TBI had better social participation outcomes at 1 year post-injury. After controlling for relevant covariates, English-speaking participants had significantly better scores in the Social Relations domain.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Teresa Gerhalter, Martijn Cloos, Anna M. Chen, Seena Dehkharghani, Rosemary Peralta, James S. Babb, Alejandro Zarate, Tamara Bushnik, Jonathan M. Silver, Brian S. Im, Stephen Wall, Steven Baete, Guillaume Madelin, Ivan I. Kirov
Summary: The relaxation properties derived from MRF, particularly T-1, showed higher utility for predicting outcomes 3 months after mild traumatic brain injury (mTBI) compared to T-2, fractional anisotropy (FA), and apparent diffusion coefficient (ADC). High T-1 at baseline and serially increasing T-1 were strong indicators of non-recovery at 3 months post-injury.
EUROPEAN RADIOLOGY
(2022)
Review
Clinical Neurology
Lynn H. Gerber, Rati Deshpande, Ali Moosvi, Ross Zafonte, Tamara Bushnik, Steven Garfinkel, Cindy Cai
Summary: This study identified a total of 17 clinical practice guidelines that address rehabilitation for people with moderate/severe TBI, with only 4 meeting all criteria. There is a lack of CPGs focusing on rehabilitation for this population, highlighting the need for more interventional trials to determine treatment effectiveness.
NEUROREHABILITATION
(2021)
Article
Psychology, Clinical
Shannon B. Juengst, Kimberly S. Erler, Dawn Neumann, Chung Lin (Novelle) Kew, Yelena Goldin, Therese M. O'Neil-Pirozzi, Amanda Rabinowitz, Janet Niemeier, Tamara Bushnik, Marcel Dijkers
Summary: Among adults with traumatic brain injury (TBI) across the lifespan, higher frequency of participation does not necessarily lead to higher satisfaction with participation. Relationships are valued more highly than other life areas by individuals with TBI, and resources to improve access to more frequent participation could enhance participation satisfaction. Cognitive functioning and frequency of participation are consistent predictors of participation satisfaction.
REHABILITATION PSYCHOLOGY
(2022)
Article
Clinical Neurology
Teresa Gerhalter, Anna M. Chen, Seena Dehkharghani, Rosemary Peralta, Fatemeh Adlparvar, James S. Babb, Tamara Bushnik, Jonathan M. Silver, Brian S. Im, Stephen P. Wall, Ryan Brown, Steven H. Baete, Ivan I. Kirov, Guillaume Madelin
Summary: The study found that while there were significant differences in sodium concentration and anisotropy in specific regions, overall patients had lower sodium concentrations compared to controls. Linear regression analysis showed significantly lower global sodium concentrations in patients, with the strongest correlation found between global grey matter sodium concentration and patient outcomes. This suggests that sodium imaging may be a non-invasive and sensitive method for assessing outcomes in mild traumatic brain injury.
BRAIN COMMUNICATIONS
(2021)
Article
Clinical Neurology
Pamela A. Kisala, Tamara Bushnik, Aaron J. Boulton, Robin A. Hanks, Stephanie A. Kolakowsky-Hayner, David S. Tulsky
JOURNAL OF HEAD TRAUMA REHABILITATION
(2019)
Article
Clinical Neurology
Aaron J. Boulton, Callie E. Tyner, Seung W. Choi, Angelle M. Sander, Allen W. Heinemann, Tamara Bushnik, Nancy Chiaravalloti, Mark Sherer, Pamela A. Kisala, David S. Tulsky
JOURNAL OF HEAD TRAUMA REHABILITATION
(2019)
Article
Psychology, Clinical
Armando Fuentes, Chelsea Schoen, Rebecca R. Kulzer, Coralynn Long, Tamara Bushnik, Joseph F. Rath
REHABILITATION PSYCHOLOGY
(2019)
Review
Orthopedics
Avtar Lal, Stephanie A. Kolakowsky-Hayner, Jamshid Ghajar, Maya Balamane
AMERICAN JOURNAL OF SPORTS MEDICINE
(2018)