Article
Rehabilitation
Dawn Neumann, Shannon B. Juengst, Charles H. Bombardier, Jacob A. Finn, Shannon R. Miles, Yue Zhang, Richard Kennedy, Amanda R. Rabinowitz, Amber Thomas, Laura E. Dreer
Summary: This study aimed to determine anxiety trajectories and predictors up to 10 years after traumatic brain injury (TBI). The results showed that factors such as race, insurance, pre-injury mental health treatment, multiple TBIs with loss of consciousness, violent injury, and years post-TBI were associated with higher levels of anxiety. Three different anxiety trajectories were identified, with the high-increasing and high-decreasing groups having consistently mild or higher anxiety scores throughout the 10-year period.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Rehabilitation
Jai Carmichael, Amelia J. Hicks, Kate Rachel Gould, Jennie Ponsford, Gershon Spitz
Summary: Objective of this study was to characterize trajectories of emotional distress across the first decade after moderate-severe traumatic brain injury (TBI) and explore relations with personal and injury-related factors. Results revealed that emotional distress is dynamic, heterogeneous, and often chronic during the first decade post-TBI, underscoring the need for ongoing monitoring and responsive treatment.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Rehabilitation
Sheryl Katta-Charles, Leah M. Adams, Nancy D. Chiaravalloti, Flora M. Hammond, Paul B. Perrin, Amanda R. Rabinowitz, Umesh M. Venkatesan, Alan H. Weintraub, Charles H. Bombardier
Summary: The study aimed to investigate the prevalence, severity, and correlates of depression, anxiety, and suicidal ideation in individuals with traumatic brain injury (TBI) before and during the COVID-19 pandemic. The findings showed no significant differences in depression, anxiety, or suicidal ideation before vs during the pandemic, and the predictors of mental health outcomes remained similar. The results suggest a general resilience and are consistent with recent studies in the general population, indicating only temporary increases in psychological distress associated with the pandemic. Although not worsened, depression, anxiety, and suicidal ideation are still prevalent and require focused treatment and research efforts.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Critical Care Medicine
Laura M. Heath, M. Rafae Kidwai, Brenda Colella, Georges Monette, Pavel Tselichtchev, Jennifer C. Tomaszczyk, Robin E. Green
Summary: This study examined the long-term trajectories of anxiety and depressive symptoms following moderate-severe traumatic brain injury (TBI), identified predictors of these trajectories, and explored their impact on 1-year return to productivity. The findings showed that there were four distinct trajectories for anxiety and depression, with most individuals experiencing stable or low levels over time. However, a subset of individuals showed rapid worsening of anxiety or depression, and those with worsening symptoms were less likely to return to productivity by 1-year post-injury.
JOURNAL OF NEUROTRAUMA
(2023)
Article
Rehabilitation
Emily L. Morrow, Nirav N. Patel, Melissa C. Duff
Summary: This study investigated the impact of the COVID-19 pandemic on individuals with chronic traumatic brain injury (TBI), finding that individuals with TBI have more difficulties coping with the pandemic, with social isolation and mental health challenges identified as key barriers.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Rehabilitation
Leia Vos, Esther Ngan, Luis Leon Novelo, Michael W. Williams, Flora M. Hammond, William C. Walker, Allison N. Clark, Andrea P. Ochoa Lopez, Shannon B. Juengst, Mark Sherer
Summary: This study analyzed a longitudinal database of traumatic brain injury patients to identify key factors associated with loss to follow-up. Missed earlier follow-ups and demographic factors, including ethnicity, education, and health insurance, were found to be strong predictors of loss to follow-up. Efforts should be made to retain participants from socially disadvantaged or minority groups.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Article
Psychology, Clinical
Amanda Rabinowitz, Tessa Hart, Julianne Wilson
Summary: The study aimed to explore the relationships between time use, emotional states, and social context in individuals with chronic moderate-severe traumatic brain injury (TBI) and depression/anxiety. Results indicated that positive affect was associated with being outside of home and with others, while socializing was related to higher negative affect. Watching TV was linked to lower negative affect but also low perceived accomplishment.
REHABILITATION PSYCHOLOGY
(2021)
Article
Rehabilitation
Adam G. Lamm, Richard Goldstein, Chloe S. Slocum, Julie K. Silver, David C. Grabowski, Jeffrey C. Schneider, Ross D. Zafonte
Summary: This study found differences in characteristics and outcomes of traumatic brain injury patients between for-profit and not-for-profit inpatient rehabilitation facilities. For-profit facilities admitted older patients with lower functional scores upon admission, but these patients showed better functional outcomes upon discharge and had higher rates of community discharge. However, for-profit facilities also had higher readmission rates.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2022)
Review
Medicine, General & Internal
Vanessa M. Young, Juan R. Hill, Michele Patrini, Stefano Negrini, Chiara Arienti
Summary: This article compiles and synthesizes the evidence on the effectiveness of rehabilitation interventions for traumatic brain injury from Cochrane systematic reviews. The results indicate a lack of high-quality evidence supporting the effectiveness of most non-pharmacological interventions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Critical Care Medicine
Stephen Breazeale, Samantha Conley, Sangchoon Jeon, Susan G. Dorsey, Joan Kearney, Brad Yoo, Nancy S. Redeker
Summary: The research identified distinct symptom cluster profiles among TOI survivors, with sociodemographic characteristics and serum BDNF concentrations being associated with membership in specific clusters.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Article
Medicine, General & Internal
Alicja Widuch-Spodyniuk, Beata Tarnacka, Bogumil Korczynski, Justyna Wisniowska
Summary: Innovative rehabilitation methods, such as robotic-assisted gait therapy (RAGT), have shown positive effects on the improvement of depression and anxiety symptoms in patients with spinal cord injuries (SCIs).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Anthony H. Lequerica, Angelle M. Sander, Monique R. Pappadis, Jessica M. Ketchum, Marissa Jaross, Stephanie Kolakowsky-Hayner, Amanda Rabinowitz, Librada Callender, Michelle Smith
Summary: This study examines the relationship between payer source, residential median household income (MHI), and outcomes at rehabilitation discharge after traumatic brain injury (TBI). The results showed that payer source was associated with rehabilitation length of stay (RLOS) and functional status at discharge. Individuals with TBI who were uninsured or had public insurance may have poorer functional status at rehabilitation discharge compared to those with private insurance or workers' compensation/auto insurance, which may be due to shorter length of stay in acute rehabilitation.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2023)
Article
Critical Care Medicine
Flora M. Hammond, James F. Malec, John D. Corrigan, Gale G. Whiteneck, Tessa Hart, Kristen Dams-O'Connor, Thomas A. Novack, Jennifer Bogner, Marie N. Dahdah, C. B. Eagye, Mitch Sevigny, Jessica M. Ketchum
Summary: This study aimed to characterize the patterns of functional change between 5 and 10 years after moderate-severe traumatic brain injury (TBI), finding that most patients experienced improvements in certain domains over time. Factors such as age at injury, post-traumatic amnesia duration, and mental health conditions were associated with changes in Functional Independence Measure (FIM) and domain change indices (DCIs). It highlights the importance of clinicians and researchers being aware of the potential for both positive and detrimental changes many years after TBI.
JOURNAL OF NEUROTRAUMA
(2021)
Article
Rehabilitation
J. Heath Wilder, Sanchita S. Gupta, Grace C. Kelly, J. Nicholas Logarbo, Santiago L. Sanchez, Garrett H. Williams, William F. Sherman
Summary: The study aimed to determine the number of patients affected by a mental illness within 3 years of a concussion and explore demographic differences that may influence a mental illness diagnosis. Using a nationwide database, patients aged 18-45 years with no previous mental illness and diagnosed with a concussion were identified, and their subsequent diagnosis of mental illness within 3 years was analyzed. The study found that within 3 years after a concussion, 48% of patients were later diagnosed with a mental illness, with higher proportions compared to the general population.
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION
(2022)
Article
Clinical Neurology
Bianca Fedele, Dean McKenzie, Gavin Williams, Robert Giles, John Olver
Summary: This study explores sleep disturbance in patients with PTA following moderate to severe TBI through ambulatory PSG and salivary melatonin assessment. Findings suggest altered sleep structure and abnormal melatonin levels in these patients, highlighting the need for further research on the relationship between PTA and sleep disturbances.
NEUROREHABILITATION AND NEURAL REPAIR
(2021)
Article
Neurosciences
Annemarie P. M. Stiekema, Britta Nijsse, Paul L. M. de Kort, Jacoba M. Spikman, Johanna M. A. Visser-Meily, Caroline M. van Heugten
Summary: This study explored the relationship between social cognitive impairments and participation restrictions in stroke survivors. While behavior regulation was found to be related to participation restrictions in the short term, other social cognitive domains did not predict participation restrictions in the long term. Further research is needed to determine if this relationship exists in patients with more severe stroke, and to identify treatment targets for improving participation by measuring social aspects.
NEUROPSYCHOLOGICAL REHABILITATION
(2021)
Article
Rehabilitation
Noah D. Silverberg, Grant L. Iverson
Summary: The survey revealed areas of expert agreement and disagreement regarding the diagnosis of mild traumatic brain injury (TBI), suggesting that observable signs are more diagnostically important than subjective symptoms, with certain symptoms and test findings consistently rated as highly important for increasing the likelihood of a mild TBI diagnosis.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Correction
Clinical Neurology
Nada Andelic, Cecilie Roe, Cathrine Brunborg Bullet, Marina Zeldovich Bullet, Marianne Lovstad, Daniel Loke, Ida M. Borgen, Daphne C. Voormolen Bullet, Emilie I. Howe, Marit V. Forslund Bullet, Hilde M. Dahl, Nicole von Steinbuechel
Summary: The original version of this article contains a mistake.
JOURNAL OF NEUROLOGY
(2021)
Article
Clinical Neurology
Nils S. van den Berg, Fransje E. Reesink, Edward H. F. de Haan, Hubertus P. H. Kremer, Jacoba M. Spikman, Rients B. Huitema
Summary: The study found that patients with neurodegenerative diseases perform worse in emotion recognition, particularly in identifying anger, disgust, fear, and sadness. Additionally, these patients exhibit more risk-taking behavior in driving simulator scenarios and the Action Selection Test. Poor recognition of fear is specifically related to making more risky decisions in situations involving direct danger.
JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY
(2021)
Review
Medicine, General & Internal
Olli Tenovuo, Ramon Diaz-Arrastia, Lee E. Goldstein, David J. Sharp, Joukje van der Naalt, Nathan D. Zasler
Summary: Assessment of TBI severity is currently based on non-specific and unreliable clinical evaluations, leading to difficulties in predicting long-term disability. Current approaches to classifying and assessing TBI severity face numerous challenges, and a new method based on risk classification and multimodal data may offer benefits for both patients and clinical research in the field.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Clinical Neurology
Lennart Riemann, Daphne C. Voormolen, Katrin Rauen, Klaus Zweckberger, Andreas Unterberg, Alexander Younsi
Summary: The study aimed to evaluate the prevalence of postconcussive symptoms and their relation to health-related quality of life in pediatric and adolescent patients with mild traumatic brain injuries who received head CT imaging. The results showed that patients requiring head CT imaging exhibited signs of increased trauma severity, with one-third experiencing postconcussive symptoms and 13% being diagnosed with PCS 6 months after injury, which was significantly associated with decreased HRQOL.
JOURNAL OF NEUROSURGERY-PEDIATRICS
(2021)
Article
Neurosciences
Harm Jan van der Horn, Namrata R. Mangina, Sandra E. Rakers, Jelmer G. Kok, Marieke E. Timmerman, Alexander Leemans, Jacoba M. Spikman, Joukje van Der Naalt
Summary: This longitudinal tractography study found microstructural changes in emotion regulation tracts among patients with mild traumatic brain injury, particularly in those without complications. However, the presence of symptoms could not be explained by these changes.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Clinical Neurology
Jurre Blaauw, Ghislaine A. Meelis, Bram Jacobs, Niels A. van Der Gaag, Korne Jellema, Kuan H. Kho, Rob J. M. Groen, Joukje van Der Naalt, Hester F. Lingsma, Heleen M. den Hertog
Summary: In patients with chronic subdural hematoma, cognitive complaints are associated with worse functional outcomes, while headache and higher Glasgow Coma Scale scores are associated with better outcomes.
ACTA NEUROLOGICA SCANDINAVICA
(2022)
Article
Rehabilitation
Sandra E. Rakers, Marieke E. Timmerman, Myrthe E. Scheenen, Myrthe E. de Koning, Harm J. van der Horn, Joukje van der Naalt, Jacoba M. Spikman
Summary: The study analyzed fatigue after mild traumatic brain injury (TBI) using latent class growth analysis (LCGA) to identify distinct recovery trajectories and investigate influencing factors. Results showed four patient clusters with different patterns of fatigue, emotional distress, and coping styles. Favorable recovery from posttraumatic fatigue was observed in 55% of mild TBI patients.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2021)
Article
Neurosciences
Jacoba M. Spikman, Harm J. van der Horn, Myrthe E. Scheenen, Myrthe E. de Koning, Mesut Savas, Thomas Langerak, Elisabeth F. C. van Rossum, Joukje van der Naalt
Summary: The study found no separate impact of mild traumatic brain injury on chronic long-term cortisol levels, suggesting that the variability in cortisol levels reflects individuals' premorbid characteristics determining coping with stress in general. Additionally, the cortisol levels of patients were negatively correlated with both passive and avoidant coping styles.
Article
Health Care Sciences & Services
Isabel R. A. Retel Helmrich, David van Klaveren, Simone A. Dijkland, Hester F. Lingsma, Suzanne Polinder, Lindsay Wilson, Nicole von Steinbuechel, Joukje van der Naalt, Andrew I. R. Maas, Ewout W. Steyerberg
Summary: Predictors of Health-Related Quality of Life (HRQoL) following traumatic brain injury (TBI) are related to physical and mental health, as well as pre-injury quality of life. Medical and injury-related characteristics play a significant role in predicting physical health, while patient-related characteristics are more important for predicting mental health and overall quality of life after TBI.
QUALITY OF LIFE RESEARCH
(2022)
Review
Behavioral Sciences
Koen Visser, Milou Koggel, Jurre Blaauw, Harm Jan van der Horn, Bram Jacobs, Joukje van der Naalt
Summary: This systematic review summarizes clinical studies on blood-based inflammatory markers after mild traumatic brain injury (mTBI) and identifies the value of inflammatory markers as biomarkers. The review suggests a distinct systemic inflammatory response following mTBI, quantifiable within 6 hours up to 12 months post-injury.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2022)
Article
Critical Care Medicine
Crispijn L. van den Brand, Kelly A. Foks, Hester F. Lingsma, Joukje van der Naalt, Bram Jacobs, Eline de Jong, Hugo F. den Boogert, Ozcan Sir, Peter Patka, Suzanne Polinder, Menno Gaakeer, Charlotte E. Schutte, Kim E. Jie, Huib F. Visee, Myriam G. M. Hunink, Eef Reijners, Meriam Braaksma, Guus G. Schoonman, Ewout W. Steyerberg, Diederik W. J. Dippel, Korne Jellema
Summary: The objective of this study was to update the CHIP decision rule for detecting (intra)cranial findings in adult patients with minor head injury. The updated model showed similar performance to the original model in detecting traumatic (intra)cranial findings and had a higher sensitivity for (potential) neurosurgical lesions or death as a result of traumatic brain injury. The updated CHIP decision rule is a good alternative for patients with minor head injury.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2022)
Article
Medicine, General & Internal
Sophie M. M. Coffeng, Kelly A. A. Foks, Crispijn L. L. van den Brand, Korne Jellema, Diederik W. J. Dippel, Bram Jacobs, Joukje van der Naalt
Summary: Currently, there is no specific CT decision rule for elderly patients with minor head injury (MHI). This study aimed to evaluate the performance of existing CT decision rules for elderly MHI patients and compare their characteristics with younger MHI patients. The 30-day mortality, clinical, and CT characteristics were assessed using four CT decision rules. Elderly patients had higher 30-day mortality (2.0% vs 0.1%) and intracranial lesions (13% vs 10%) compared to younger patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Psychology, Clinical
Sebastian A. Balart-Sanchez, Mayra Bittencourt-Villalpando, Joukje van der Naalt, Natasha M. Maurits
Summary: This systematic review examines the neural correlates of cognitive reserve estimates using ECOG, EEG, and MEG. The findings show that (M)EEG measures are related to CR estimates, particularly in healthy individuals. The nature of this relationship depends on the population and task studied, suggesting a need for further research.
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY
(2021)
