Article
Health Care Sciences & Services
Eva Hobeika, Diana Malaeb, Sahar Obeid, Pascale Salameh, Elie Hobeika, Miguella Outayek, Marwan Akel, Nelly Kheir, Zaki Sleiman, Habib Barakat, Souheil Hallit
Summary: It is important to assess the psychometric properties of depression and anxiety scales in Arabic and identify factors associated with postnatal depression (PPD) and anxiety (PPA) among Lebanese women. In this cross-sectional study, the EPDS and PASS scales showed good convergent validity and explained a significant amount of variance. Higher postpartum anxiety, insomnia, hypotension during pregnancy, and higher birth order were significantly associated with higher postpartum depression. Higher postpartum depression was significantly associated with higher postpartum anxiety, while planned pregnancy and regular infant feeding were associated with lower postpartum anxiety.
Article
Medicine, General & Internal
Monira Alwhaibi, Yazed AlRuthia, Ibrahim Sales
Summary: This study examined the impact of depression and anxiety on health-related quality of life (HRQoL) in different cancer groups using nationally representative US data. The results showed that cancer patients with comorbid depression and anxiety had the lowest scores in both physical and mental components of HRQoL. Moreover, cancer patients with depression and/or anxiety were more likely to have lower mental component scores compared to those with cancer only. Routine screening for depression and anxiety should be conducted by healthcare providers, and early psychiatric interventions may positively impact patients' mental well-being and HRQoL.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Anders Carlander, Mats Lekander, Gordon J. G. Asmundson, Steven Taylor, Roger Olofsson Bagge, Ann-Sophie Lindqvist Bagge
Summary: This study translated, replicated, and validated the COVID Stress Scales (CSS) in a Swedish national sample and examined its convergent and discriminant validity in relation to anxiety, health anxiety, depression, and stress. The results indicated that the Swedish translation of CSS had good psychometric properties and consisted of 5 correlated factors. The findings support the cross-cultural validity of CSS and its potential utility in understanding emotional challenges posed by pandemics.
Article
Clinical Neurology
Johanna Junker, James Hall, Brian D. Berman, Marie Vidailhet, Emmanuel Roze, Tobias Baeumer, Irene A. Malaty, Aparna Wagle Shukla, Joseph Jankovic, Stephen G. Reich, Alberto J. Espay, Kevin R. Duque, Neepa Patel, Joel S. Perlmutter, H. A. Jinnah, Valerie Dystonia Coalition Study Group, Valerie Brandt, Norbert Brueggemann
Summary: This study aimed to determine longitudinal predictors of health-related quality of life in patients with isolated dystonia. The results showed that depressive symptoms, generalized anxiety disorder, and social anxiety disorder significantly impacted HR-QoL, highlighting the importance of incorporating mental health treatment into treatment regimens.
JOURNAL OF NEUROLOGY
(2023)
Review
Medicine, General & Internal
Alejandro Dominguez-Rodriguez, David Villarreal-Zegarra, Sofia Malaquias-Obregon, Paulina Erika Herdoiza-Arroyo, Joel Omar Gonzalez-Cantero, Sarah Margarita Chavez-Valdez, Roberto Rafael Cruz-Martinez
Summary: Human actions have influenced climate change and caused negative impacts on communities and individual health. Despite the development of assessment tools, evidence on the impact of climate change on mental health is still limited. This scoping review aims to describe existing instruments in this area.
Article
Clinical Neurology
Emma Kofoed Lauridsen, Urszula Maria Ciochon, Anders Tolver, Mark Bech Knudsen, Laura Giraldi, Jacob Bertram Springborg, Lars Bogeskov, Lars Poulsgaard, Tiit Mathiesen, Karin Piil, Kare Fugleholm
Summary: This observational study aimed to investigate long-term health-related quality of life, anxiety, and depression in patients with subfrontal meningiomas who underwent a bifrontal craniotomy approach. The results showed that patients with subfrontal meningiomas had better long-term postoperative health-related quality of life and were less likely to have anxiety or depression. The number of symptoms at diagnosis and postoperative discharge status were significant factors affecting long-term health-related quality of life, while tumor and peritumoral brain edema volumes were not prognostic factors.
JOURNAL OF NEUROSURGERY
(2023)
Article
Psychology, Multidisciplinary
Leif Edward Ottesen Kennair, Roger Hagen, Odin Hjemdal, Audun Havnen, Truls Ryum, Stian Solem
Summary: This study reveals a close association between symptoms of anxiety and depression, insomnia, and health-related quality of life among older adults in a large municipality in Norway.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Psychiatry
Nicola Julia Aebi, Guenther Fink, Kaspar Wyss, Matthias Schwenkglenks, Iris Baenteli, Seraina Caviezel, Anja Studer, Sarah Trost, Sibil Tschudin, Rainer Schaefert, Gunther Meinlschmidt
Summary: A study found that non-COVID-19 inpatients at Swiss general hospitals were more likely to experience distress related to leisure time and loneliness during periods of heightened COVID-19 restrictions. However, there was no significant change in mental health or social support.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Multidisciplinary
Giulia Agostinelli, Barbara Muzzatti, Samantha Serpentini, Michele Spina, Maria Antonietta Annunziata
Summary: This study examined psychological distress in lymphoma survivors and identified variables associated with it, such as gender, living situation, diagnosis type, treatment methods, sleep quality, exercise frequency, and medication use. Early identification of anxiety and depression is important to provide timely psychological support to those in need.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Public, Environmental & Occupational Health
Rhiannon K. Patten, Michaela C. Pascoe, Alba Moreno-Asso, Russell A. Boyle, Nigel K. Stepto, Alexandra G. Parker
Summary: The review suggests that exercise interventions can improve health-related quality of life and alleviate symptoms of depression and anxiety in women with PCOS. However, more high-quality trials are needed to determine effective exercise protocols for this population and to guide clinical practice.
Article
Public, Environmental & Occupational Health
Monira Alwhaibi, Bander Balkhi, Yazed AlRuthia
Summary: This study investigated the relationship between anxiety and depression and health-related quality of life (HRQoL) in adults with migraines. The findings showed that a significant proportion of migraineurs also experienced depression and anxiety, which were negatively associated with HRQoL. Migraineurs with comorbid depression and anxiety had the lowest HRQoL scores. Furthermore, regular exercise was found to have a positive impact on HRQoL among migraine sufferers.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Multidisciplinary Sciences
Katarzyna Adamczyk, D. Angus Clark, Julia Pradelok
Summary: The study found that the Polish-language version of the CSS is psychometrically robust and largely invariant across countries and time. It also revealed positive relationships between the CSS-PL and COVID-19 fear, health anxiety, obsessive compulsive symptoms, anxiety, depression, and intent to receive a COVID-19 vaccine. This study provides valuable information about the items and scales of the CSS, laying the groundwork for future research on COVID stress in different populations over time.
Article
Clinical Neurology
A. Herten, B. Chen, D. Saban, A. Santos, K. Wrede, R. Jabbarli, Y. Zhu, B. Schmidt, C. Kleinschnitz, M. Forsting, U. Sure, P. Dammann
Summary: Patients with untreated cavernous malformation of the CNS (CCM) have decreased health-related quality of life compared to the German normal population, even when not experiencing functional impairment or neurological symptoms. Mental health scores are significantly correlated with the mental component score and individual perception of the CCM.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Health Care Sciences & Services
Anat Amit Aharon, Ilana Dubovi, Angela Ruban
Summary: The study found that there were significantly higher levels of anxiety and lower health-related quality of life in Italian participants. The variables of anxiety and depression predicted a decline in health-related quality of life, while physical activity was identified as a protective factor.
QUALITY OF LIFE RESEARCH
(2021)
Article
Environmental Sciences
Xiang Li, Daniel T. L. Shek, Esther Y. W. Shek
Summary: The Chinese version of DASS has good psychometric properties in Hong Kong university students, with gender, cohort, and well-being factors associated with psychological morbidity.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Oncology
Rafal Watrowski, Dan Cacsire Castillo-Tong, Eva Obermayr, Robert Zeillinger
ANTICANCER RESEARCH
(2020)
Article
Nutrition & Dietetics
Malgorzata Mizgier, Rafal Watrowski, Justyna Opydo-Szymaczek, Elzbieta Jodlowska-Siewert, Giovanni Lombardi, Witold Kedzia, Grazyna Jarzabek-Bielecka
Summary: The study found positive correlations between dietary fats and hormone parameters in PCOS and healthy girls, as well as positive correlation between SHBG and protein intake and negative correlation between SHBG and carbohydrate intake. In PCOS patients, an inverse correlation was observed between androgen concentrations and work/school and/or leisure time physical activity.
Article
Medicine, General & Internal
Stoyan Kostov, Ilker Selcuk, Angel Yordanov, Yavor Kornovski, Hakan Yalcin, Stanislav Slavchev, Yonka Ivanova, Svetla Dineva, Deyan Dzhenkov, Rafal Watrowski
Summary: Lymphadenectomy is an important surgical treatment for gynecological cancers. Pelvic and paraaortic lymphadenectomy are commonly performed procedures that help with staging, prognosis, and postoperative management. Anatomical variations of the vessels in the paraaortic region are common and can lead to complications during the surgery. It is crucial for surgeons to have detailed knowledge of these variations to prevent iatrogenic vessel injury.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Stoyan Kostov, Ilker Selcuk, Rafal Watrowski, Yavor Kornovski, Hakan Yalcin, Stanislav Slavchev, Yonka Ivanova, Deyan Dzhenkov, Angel Yordanov
Summary: Except for early-stage tumors and fertility preservation, the surgical treatment of gynecological malignancies is not limited to the affected organ. Dissecting tissues in the region of metastatic iliac lymph nodes or gynecological tumors near the pelvic sidewall is necessary. In addition, surgeries for deep infiltrating endometriosis or oncological procedures often require dissection of the pelvic sidewall. Precise dissection and detailed anatomical knowledge are crucial. Terminology regarding the pelvic sidewall is controversial, and this study aims to define a new term and boundaries of a potential avascular space, the medial psoas space, for surgical guidance.
Review
Biotechnology & Applied Microbiology
Stoyan Kostov, Rafal Watrowski, Yavor Kornovski, Deyan Dzhenkov, Stanislav Slavchev, Yonka Ivanova, Angel Yordanov
Summary: Hereditary cancer syndromes, which result from low penetrant polymorphisms or single gene disorders, account for approximately 5-10% of all cancers. Significant progress has been made in the evaluation and management of these syndromes in the past decade. However, hereditary syndromes associated with gynecologic malignancies present a challenge for oncogynecologists, who tend to focus more on staging, histological type, and treatment options rather than considering inherited cancers and obtaining detailed family histories.
ONCOTARGETS AND THERAPY
(2022)
Article
Oncology
Rafal Watrowski, Eva Obermayr, Christine Wallisch, Stefanie Aust, Nicole Concin, Elena Ioana Braicu, Toon Van Gorp, Annette Hasenburg, Jalid Sehouli, Ignace Vergote, Robert Zeillinger
Summary: In this study, new proteomic-based models for non-invasive diagnosis of ovarian cancer (OC) were developed and validated. These models showed excellent performance in postmenopausal women but performed poorly in premenopausal patients and those with normal CA125 levels. Comparison with other algorithms and markers revealed no clear superiority of any model.
Review
Medicine, General & Internal
Salvatore Giovanni Vitale, Rafal Watrowski, Fabio Barra, Maurizio Nicola D'Alterio, Jose Carugno, Thozhukat Sathyapalan, Ilker Kahramanoglu, Enrique Reyes-Munoz, Li-Te Lin, Bulent Urman, Simone Ferrero, Stefano Angioni
Summary: Abnormal uterine bleeding is a common symptom in perimenopausal women, and various treatment options exist to alleviate symptoms and improve quality of life. Hysterectomy offers definitive symptom relief, while uterus-preserving minimally invasive treatments have high patient satisfaction but still carry the risk of recurrence and further intervention.
Article
Obstetrics & Gynecology
Radmila Sparic, Zoran Bukumiric, Radomir Stefanovic, Andrea Tinelli, Stoyan Kostov, Rafal Watrowski
Summary: This study evaluated the factors influencing long-term health-related quality of life (HRQoL) after excisional treatments for squamous intraepithelial cervical lesions (SIL). The results showed that women interested in reproduction had higher HRQoL scores, while women without pregnancy desire had lower HRQoL scores. Anxiety and depression were also found to be related to HRQoL.
JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2022)
Review
Medicine, General & Internal
Veronika Guenther, Leila Allahqoli, Rafal Watrowski, Nicolai Maass, Johannes Ackermann, Soeren von Otte, Ibrahim Alkatout
Summary: The human microbiome, particularly the vaginal microbiome, has gained importance in reproductive medicine due to its potential influence on infertility and implantation failure. Non-Lactobacillus-dominated microbiomes have been associated with dysbiosis and may negatively impact reproductive outcomes. Screening the microbiome and administering antibiotic and/or probiotic treatment could improve pregnancy outcomes.
Review
Biochemistry & Molecular Biology
Salvatore Giovanni Vitale, Anna Maria Fulghesu, Mislav Mikus, Rafal Watrowski, Maurizio Nicola D'Alterio, Li-Te Lin, Mohsin Shah, Enrique Reyes-Munoz, Thozhukat Sathyapalan, Stefano Angioni
Summary: MicroRNAs (miRNAs) play crucial regulatory roles in tissue development, differentiation, and metabolic processes. In the context of PCOS, altered miRNA levels have been associated with hormonal changes, glucose and lipid metabolism, and fertility issues. This systematic review provides an overview of miRNA expression, hormonal changes, and metabolic correlations in PCOS, highlighting the potential of miRNAs as therapeutic targets and diagnostic markers.
Editorial Material
Surgery
Rafal Watrowski, Stoyan Kostov, Radmila Sparic
FRONTIERS IN SURGERY
(2022)
Review
Medicine, General & Internal
Stoyan Kostov, Ilker Selcuk, Rafal Watrowski, Svetla Dineva, Yavor Kornovski, Stanislav Slavchev, Yonka Ivanova, Deyan Dzhenkov, Angel Yordanov
Summary: Ovarian cancer is a leading cause of death in gynecological malignancies, often presenting at an advanced stage. The most common routes of spread are peritoneal and lymphatic dissemination. The right subphrenic space is a target site for peritoneal metastases, particularly in the right upper quadrant. Complete cytoreduction is the most important prognostic factor.
Article
Surgery
Stoyan Kostov, Yavor Kornovski, Rafal Watrowski, Stanislav Slavchev, Yonka Ivanova, Angel Yordanov
Summary: Ovarian cancer is a common cause of death in women and usually spreads through the peritoneal dissemination and direct invasion. Optimal cytoreduction and adjuvant chemotherapy are the main treatment strategies. The radical surgical cytoreduction procedure, known as the Hudson procedure, has been modified over the years, but there are still disagreements and gaps regarding certain surgical steps. The purpose of this article is to outline the critical steps of the Hudson procedure and discuss the associated controversies and perioperative morbidity.
Article
Medicine, General & Internal
Stoyan Kostov, Yavor Kornovski, Vesela Ivanova, Deyan Dzhenkov, Dimitar Metodiev, Rafal Watrowski, Yonka Ivanova, Stanislav Slavchev, Dimitar Mitev, Angel Yordanov
Summary: Uterine corpus sarcomas are rare malignant neoplasms which pose challenges in diagnosis and treatment due to the small number of clinical trials, lack of evidence-based data, and insufficient interest from the pharmaceutical industry. The development of clinical practice guidelines and treatment protocols is also difficult due to the low frequency of these malignancies.
CLINICS AND PRACTICE
(2021)
Review
Surgery
Rafal Watrowski, Stoyan Kostov, Ibrahim Alkatout
Summary: Laparoscopic surgery is widely used in gynecology and general surgery, but may be associated with complications. Adverse events can be related to laparoscopic entry, pneumoperitoneum, or the use of instruments. This review provides comprehensive information on surgical complications in laparoscopy with a special focus on gynecology.
VIDEOSURGERY AND OTHER MINIINVASIVE TECHNIQUES
(2021)