4.4 Article

OC-125 immunostaining in endometriotic lesion samples

Journal

ARCHIVES OF GYNECOLOGY AND OBSTETRICS
Volume 281, Issue 1, Pages 43-47

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00404-009-1055-7

Keywords

Endometriosis; OC-125 immunoreactivity; Laparoscopy surgery; CA-125; Pelvic pain

Ask authors/readers for more resources

To determine the presence of OC-125 staining in endometriotic lesions and to verify whether there is an association with endometriosis stage. Thirteen patients from the Family Planning programs (group I) and 53 patients from the Chronic Pelvic Pain outpatient clinic (group II) were studied. Endometriotic lesions were excised from areas of endometriosis incidence and studied by histopathological assay and by immunohistochemistry for OC-125 staining. The histopathological study disclosed that all patients from group I had minimal/mild endometriosis. In group II, 39.6% had minimal/mild endometriosis, and 60.4% had moderate/severe endometriosis. OC-125 staining was negative in all samples from group I. In group II, OC-125 staining was positive in 52.4% patients with minimal/mild endometriosis and in 81.2% with moderate/severe endometriosis. The data suggest that the OC-125 antibody is probably related to endometriosis activity and, consequently, to the progression and severity of the illness.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Medicine, Research & Experimental

Folate metabolism abnormalities in infertile patients with endometriosis

Tarciana Guedes, Aline A. Santos, Felipe H. Vieira-Neto, Bianca Bianco, Caio P. Barbosa, Denise M. Christofolini

Summary: This study aimed to investigate the correlation between genetic variants, homocysteine levels, and assisted reproduction results. It was found that patients with endometriosis had specific genetic markers, lower levels of homocysteine, and a tendency towards better clinical pregnancy outcomes.

BIOMARKERS IN MEDICINE (2022)

Review Obstetrics & Gynecology

Urodynamic profile of voiding in patients with pelvic organ prolapse after surgery: a systematic review with meta-analysis

Danilo Budib Lourenco, Hugo Octaviano Duarte-Santos, Alexandre Dib Partezani, Saulo Borborema Teles, Bianca Bianco, Luis Augusto Seabra Rios, Gustavo Caserta Lemos, Arie Carneiro

Summary: This study conducted a systematic review and meta-analysis to investigate the urodynamic changes in patients undergoing surgical correction for pelvic organ prolapse (POP). The results showed that surgery improved bladder-emptying parameters and reduced the prevalence of detrusor overactivity (DO), while sling placement may enhance obstructive parameters.

INTERNATIONAL UROGYNECOLOGY JOURNAL (2023)

Review Endocrinology & Metabolism

Effect of thyroid function on assisted reproduction outcomes in euthyroid infertile women: A single center retrospective data analysis and a systematic review and meta-analysis

Viviane Rosado Negreiros D'Assuncao, Erik Montagna, Luis Eduardo Negreiros D'Assuncao, Maria Madalena Pessoa Caldas, Denise Maria Christofolini, Caio Parente Barbosa, Ricardo Andre Medeiros Negreiros, Antonio Simone Lagana, Renato de Oliveira, Bianca Bianco

Summary: This study evaluated different gestational outcomes in euthyroid infertile women without autoimmune thyroid disease undergoing in vitro fertilization (IVF). Results showed that variation in TSH levels within the normal range was not associated with pregnancy and delivery rates.

FRONTIERS IN ENDOCRINOLOGY (2022)

Letter Dermatology

Prevalence of filaggrin gene polymorphisms (exon-3) in patients with atopic dermatitis in a multiracial Brazilian population

Cristina Marta Maria Laczynski, Carlos D'Apparecida Santos Machado Filho, Helio Amante Miot, Denise Maria Christofolini, Itatiana Ferreira Rodart, Paulo Ricardo Criado

ANAIS BRASILEIROS DE DERMATOLOGIA (2023)

Article Urology & Nephrology

Impact of COVID-19 pandemic on prostate cancer outcomes at an uro-oncology referral center

Guilherme Miranda Andrade, Lucas Sesconetto, Rafael Benjamim Rosa da Silva, Gabriela Guimaraes Rodrigues dos Santos, Paulo Priante Kayano, Willy Baccaglini, Murilo Borges Bezerra, Bianca Bianco, Gustavo Caserta Lemos, Arie Carneiro

Summary: This retrospective study evaluated the oncologic results of prostate cancer patients before and during the COVID-19 pandemic. The results showed no significant differences in clinical staging, pathological outcomes, and postoperative complications between the two groups. The study concluded that the pandemic did not worsen the features of prostate cancer.

INTERNATIONAL BRAZ J UROL (2023)

Article Dentistry, Oral Surgery & Medicine

Oral health-related quality of life in patients aged 8 to 19 years with cleft lip and palate: a systematic review and meta-analysis

Augusto Garcia de Oliveira Junior, Erik Montagna, Victor Zaia, Caio Parente Barbosa, Bianca Bianco

Summary: This study assessed the impact of treatment for cleft lip and palate on the oral health-related quality of life in children and adolescents. The results showed that the overall oral health-related quality of life was slightly worse in patients with cleft lip and palate compared to the healthy control group, with the most affected domains being functional, emotional, and social.

BMC ORAL HEALTH (2023)

Article Obstetrics & Gynecology

Does vaginal surgery for correction of pelvic organ prolapse improve urinary function? A prospective cohort study

Danilo B. Lourenco, Hugo O. D. Santos, Elizabeth Y. Hirakawa, Luis Augusto S. Rios, Gustavo C. Lemos, Bianca Bianco, Arie Carneiro

Summary: Pelvic organ prolapse surgery reduced the prevalence of urgency symptoms, and all questionnaires on urinary symptoms showed clinically significant improvement. Vaginal surgery for POP, even combined with MUS, significantly reduced PVR volume and improved urgency symptoms.

INTERNATIONAL UROGYNECOLOGY JOURNAL (2023)

Article Medicine, General & Internal

Implication of FSHB rs10835638 variant in endometriosis in Brazilian women

Bianca Bianco, Flavia Altheman Loureiro, Camila Martins Trevisan, Denise Maria Christofolini, Antonio Simone Lagana, Caio Parente Barbosa

Summary: This study found an association between the follicle-stimulating hormone subunit beta gene rs10835638 variant (c.-211G>T) and the development of minimal/mild endometriosis in Brazilian women.

EINSTEIN-SAO PAULO (2023)

Review Obstetrics & Gynecology

Oxidative homeostasis in follicular fluid and reproductive outcomes - from bench to bedside

Ivana Zec, Marina Sprem Goldstajn, Krunoslav Kuna, Mislav Mikus, Guglielmo Stabile, Bianca Bianco, Giovanni Buzzaccarini, Antonio Simone Lagana

Summary: This review focuses on the alterations of redox homeostasis in the follicular fluid during female reproduction and its potential impact on IVF outcomes. Studies suggest a shift towards enhanced oxidizing modification and antioxidative consumption in the follicular fluid of women undergoing IVF treatment. However, the precise role of redox imbalance in oocyte competence and IVF outcomes remains uncertain.

MENOPAUSE REVIEW-PRZEGLAD MENOPAUZALNY (2022)

Meeting Abstract Obstetrics & Gynecology

IMPACT OF TSH LEVELS ON IN VITRO FERTILIZATION OUTCOMES IN EUTHYROID INFERTILE WOMEN

Viviane Rosado Rosado Negreiros D'Assuncao, Caio Barbosa, Luis Eduardo Negreiros Negreiros D'Assuncao, Denise Christofolini, Ricardo Medeiros Negreiros, Renato Oliveira, Bianca Bianco

FERTILITY AND STERILITY (2022)

Article Medicine, General & Internal

Radical prostatectomies for treatment of prostate cancer: trends in a ten-year period in public health services in the city of Sao Paulo, Brazil

Lucas Seiti Takemura, Alan Roger Gomes Barbosa, Breno Santos Amaral, Alvaro Alexandre Dias Bosco, Danilo Budib Lourenco, Marcelo Apezzato, Joao Arthur Brunhara Alves Barbosa, Eliney Ferreira Faria, Bianca Bianco, Gustavo Caserta Lemos, Arie Carneiro

Summary: This study analyzed the characteristics of public health services related to radical prostatectomy, focusing on hospital volume and academic/non-academic centers. The results showed that academic centers had shorter hospital stays, while high-volume centers had higher hospitalization costs. There were no significant differences in other aspects between centers with different surgery volumes and academic/non-academic centers.

EINSTEIN-SAO PAULO (2022)

Meeting Abstract Urology & Nephrology

URODYNAMIC PROFILE OF VOIDING IN PELVIC ORGAN PROLAPSE PATIENTS AFTER SURGERY: A SYSTEMATIC REVIEW WITH META-ANALYSIS

Hugo Santos, Danilo Lourenco, Alexandre Partezani, Saulo Teles, Lucas Takemura, Felipe Gushiken, Guilherme Andrade, Bianca Bianco, Luis Rios, Gustavo Lemos, Arie Carneiro

JOURNAL OF UROLOGY (2022)

Meeting Abstract Urology & Nephrology

A PROSPECTIVE TRIAL OF MULTIPARAMETRIC MAGNETIC RESONANCE OF THE PROSTATE USE TO AVOID BIOPSIES IN PATIENTS WITH ELEVATED PROSTATE SPECIFIC ANTIGEN AND SURGICAL INDICATION FOR BENIGN PROSTATIC HYPERPLASIA

Marcelo Wroclawski, Lucas Takemura, Felipe Gushiken, Breno Amaral, Paulo Kayano, Ronaldo Baroni, Bianca Bianco, Arie Carneiro, Gustavo Lemos

JOURNAL OF UROLOGY (2022)

Article Medicine, General & Internal

Benign prostatic hyperplasia surgical treatment trends in the Public Health System in Sao Paulo, Brazil

Alan Roger Gomes Barbosa, Lucas Seiti Takemura, Breno Santos Amaral, Marcelo Langer Wroclawski, Wladimir Alfer, Antonio Otero Gil, Jose Monteiro, Danilo Budib Lourenco, Jonathan Doyun Cha, Marcelo Apezzato, Joao Arthur Brunhara Alves Barbosa, Bianca Bianco, Gustavo Caserta Lemos, Arie Carneiro

Summary: This study aimed to compare the number of surgeries, mortality rate, length of hospital stay, and costs between transurethral resection of the prostate and open prostatectomy for the treatment of benign prostatic hyperplasia. The findings suggest the importance of investing in specialized centers, which could be potential referral centers for surgical cases.

EINSTEIN-SAO PAULO (2022)

Article Medicine, General & Internal

Impact of blood levels of progesterone on the day of ovulation onset on clinical, laboratory and reproductive parameters of young patients undergoing assisted reproduction: a cross-sectional study

Renata Garcia Olmos Fernandez, Caio Parente Barbosa, Denise Maria Christofolini, Luiz Vinicius de Alcantara Sousa, Renato de Oliveira, Bianca Bianco

Summary: This study aimed to assess the association between the level of progesterone on the day of human chorionic gonadotropin administration and clinical and laboratory characteristics in patients with a good prognosis for in vitro fertilization. The results showed weak positive correlations between progesterone levels and the number of follicles larger than 14mm, retrieved oocytes, and oocytes in metaphase II. However, there was no significant association with body mass index, stimulation protocols, embryo quality, or pregnancy rate.

EINSTEIN-SAO PAULO (2022)

No Data Available