Article
Food Science & Technology
Zhihao Liu, Jenna Shi, Jiawei Wan, Quynchi Pham, Zhi Zhang, Jianghao Sun, Liangli Yu, Yaguang Luo, Thomas T. Y. Wang, Pei Chen
Summary: This study provides the first report on the polyphenol and glucosinolate composition of kale and broccoli microgreens grown in different environments. The results showed a clear variation in secondary metabolites between growth chamber and windowsill conditions, suggesting that the growing environment affects the composition of health-beneficial components in vegetables.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Biochemical Research Methods
Xuyang Dong, Xiujuan Wang, Xiuli Xu, Yaxuan Song, Xuemei Nie, Wei Jia, Wei Guo, Feng Zhang
Summary: In this study, untargeted metabolomics approach based on UHPLC-HRMS was used to investigate the differences in cage duck eggs and sea duck eggs. A model for identifying sea duck eggs was established, and three potential markers were found to have higher content in sea duck eggs, which were confirmed to be reliable. The quantitative analysis showed that the content difference of these markers in farm samples were consistent with the concentration changes measured in experimental samples.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2021)
Article
Plant Sciences
Chenghuan Yan, Yan Huang, Shuting Zhang, Lei Cui, Zhenbiao Jiao, Zhaoxin Peng, Xiaozhou Luo, Yun Liu, Zhengming Qiu
Summary: This study comprehensively investigated the intact glucosinolates (GSLs) in radish using UHPLC-HRMS/MS and UHPLC-QqQ-MS/MS methods, and identified 15 intact GSLs, including four major GSLs and three isomers. The content of GSLs in taproots showed a fluctuating increase throughout the growth stages, while it steadily decreased in the leaves. The biosynthetic pathways of radish-specific GSLs were also elucidated.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Chemistry, Applied
Koksal Demir, Golge Sarikamis, Gamze Cakirer Seyrek
Summary: This study investigated the effects of red, blue, far-red LED lights and their combinations on the growth, nutritional quality, and glucosinolates of brassica microgreens. Different microgreen plants exhibited different growth and quality characteristics under different light conditions.
Article
Food Science & Technology
Wenjing Zeng, Jing Yang, Guochao Yan, Zhujun Zhu
Summary: Adding CaSO4 into NaCl solution can increase the yield of broccoli microgreens, alleviate the adverse effects of NaCl stress on sulforaphane and nitrate content, and induce the accumulation of Ca and S.
Article
Chemistry, Applied
Ahui Xue, Wenjing Liang, Shide Wen, Yuanyuan Gao, Xueyong Huang, Yuzhen Tong, Yingbin Hao, Liping Luo
Summary: The study found that blue light can improve the accumulation of secondary metabolites in broccoli sprouts, with the R5B5 treatment being the most effective. The establishment of the EESI-MS method enables simultaneous and rapid detection of secondary metabolites in broccoli sprouts, especially GLs.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2021)
Article
Food Science & Technology
Yuchao Feng, Xia Fan, Shu Zhang, Tong Wu, Lu Bai, Haoyu Wang, Yantao Ma, Xin Guan, Changyuan Wang, Hongzhi Yang
Summary: Different varieties and origins of Chenopodium quinoa Willd have significant differences in metabolic characteristics and texture properties, with lipid, amino acid, and polyphenol contents being the main factors contributing to these differences.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Biochemistry & Molecular Biology
Katarina A. Jones, Allison J. Richard, J. Michael Salbaum, Susan Newman, Richard Carmouche, Sara Webb, Annadora J. Bruce-Keller, Jacqueline M. Stephens, Shawn R. Campagna
Summary: Herbal remedies, such as fenugreek seeds, have shown potential therapeutic effects on metabolic conditions like obesity and Type 2 Diabetes. This study found that fenugreek supplementation resulted in significant alterations in the gut microbiome and metabolic pathways, suggesting its beneficial effects may be attributed to these changes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Analytical
Xing-Cai Wang, Xing-Ling Ma, Jia-Nan Liu, Yang Zhang, Jia-Ni Zhang, Meng-Han Ma, Feng-Lian Ma, Yong-Jie Yu, Yuanbin She
Summary: This study provides a comprehensive evaluation of several advanced UHPLC-HRMS data analysis tools in plant metabolomics. Results show that AntDAS provides the most acceptable feature extraction, compound identification, and quantification results in targeted compound analysis. For complex plant datasets, both MS-DIAL and AntDAS are more reliable than other tools.
ANALYTICA CHIMICA ACTA
(2023)
Article
Plant Sciences
Priya Yadav, Rahul Prasad Singh, Hissah Abdulrahman Alodaini, Ashraf Atef Hatamleh, Gustavo Santoyo, Ajay Kumar, Rajan Kumar Gupta
Summary: The increasing global population has raised the need for higher agricultural productivity to meet the demand for food production. However, abiotic and biotic stresses pose challenges and reduce crop yields, affecting economic and social welfare. Drought severely impacts agriculture, resulting in unproductive soil, reduced farmland, and threatened food security. Focus has recently turned towards cyanobacteria, specifically Nostoc calcicola BOT1, in rehabilitating degraded land due to their ability to enhance soil fertility and prevent erosion. This study investigated the effects of dehydration treatments on the physicochemical properties of N. calcicola BOT1, and demonstrated the accumulation of biochemical and non-enzymatic antioxidants during dehydration, which could be utilized to stabilize unfavorable environmental conditions. Additionally, the strain N. calcicola BOT1 holds promise as a biofertilizer for semi-arid regions.
FRONTIERS IN PLANT SCIENCE
(2023)
Article
Food Science & Technology
Ane Arrizabalaga-Larranaga, Guillem Campmajo, Javier Saurina, Oscar Nunez, Francisco Javier Santos, Encarnacion Moyano
Summary: The study used the UHPLC-APCI-HRMS method for the geographical origin authentication of paprika based on capsaicinoids and carotenoids determination, achieving an authentication rate of 80.9%.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Agriculture, Multidisciplinary
Anli Wang, Xinyu Chen, Shanyun Wu, Wei Jia, Jingjing Jiao, Yu Zhang
Summary: This study evaluated the metabolic profiles in rat serum after exposure to acrylamide, revealing significant changes in metabolites in rats exposed to high doses of acrylamide, mainly affecting pathways such as the citrate cycle, amino acid biosynthesis, and pyruvate metabolism.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Analytical
Sothearath Sorng, Stephane Balayssac, Saida Danoun, Gaetan Assemat, Alexandre Mirre, Valerie Cristofoli, Anne-Cecile Le Lamer, Valerie Jullian, Veronique Gilard, Nicolas Fabre, Robert Martino, Myriam Malet-Martino
Summary: This study evaluated the quality of turmeric dietary supplements by analyzing their chemical composition using UHPLC-MS and H-1 NMR. The results showed significant variability in the composition of these supplements and found that the actual quantities of curcuminoids and piperine in the supplements often did not match the claimed amounts.
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
(2022)
Article
Food Science & Technology
Leos Uttl, Kamila Bechynska, Mona Ehlers, Vaclav Kadlec, Klara Navratilova, Zbynek Dzuman, Carsten Fauhl-Hassek, Jana Hajslova
Summary: This study presents a reliable and robust metabolic fingerprinting-based strategy for varietal authentication of wine. By analyzing commercial wine samples and building classification models, the stability of the models over time was verified. Additionally, several important varietal markers were tentatively identified.
Article
Chemistry, Applied
Wei Jia, Xin Wang, Xixuan Wu, Lin Shi
Summary: This study investigated the metabolic pathways and nutritional quality of goat milk contaminated with sodium perchlorate using untargeted metabolomics and proteomics methods. The results showed that the levels of several metabolites and crucial enzymes related to milk quality were altered after sodium perchlorate treatment, leading to a degradation in nutritional quality.
Article
Agriculture, Multidisciplinary
Yanfang Li, Zhihao Liu, Gillian Manka Tamia, Xiaohua He, Jianghao Sun, Pei Chen, Seong-Ho Lee, Thomas T. Y. Wang, Boyan Gao, Zhuohong Xie, Liangli Lucy Yu
Summary: Different types of phenolic compounds in tomato seeds were analyzed, with the insoluble bound fraction showing stronger antioxidant activity and anti-cancer cell proliferation effects. The soluble free and insoluble bound fractions significantly inhibited colorectal cancer cell proliferation, providing a basis for the future use of tomato seeds as nutraceuticals in dietary supplements and functional foods.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Agriculture, Multidisciplinary
Yanfang Li, Zhihao Liu, Melody Zeng, Alem El Kadiri, Jhongyan Huang, Ashley Kim, Xiaohua He, Jianghao Sun, Pei Chen, Thomas T. Y. Wang, Yaqiong Zhang, Boyan Gao, Zhuohong Xie, Liangli Lucy Yu
Summary: In this study, clove water and ethanol extracts were found to have potential in reducing the risk of SARS-CoV-2 infection by suppressing the binding between spike protein and ACE2, reducing ACE2 availability, and scavenging free radicals. Clove water extract showed stronger inhibitory effects and free radical scavenging activities than ethanol extract.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Review
Agriculture, Multidisciplinary
Zhihao Liu, Mengliang Zhang, Pei Chen, James M. Harnly, Jianghao Sun
Summary: This review discusses the applications of mass spectrometry (MS) techniques in food and agricultural research, including targeted and nontargeted analysis. It summarizes recent publications in the field, such as flow injection MS fingerprinting, chromatography-tandem MS metabolomics, and ambient mass spectrometry. The review also highlights the development of MS data deconvolution software packages and databases for metabolomic studies.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Biochemistry & Molecular Biology
Zhihao Liu, Roderick Moore, Ying Gao, Pei Chen, Liangli Yu, Mengliang Zhang, Jianghao Sun
Summary: This study used UHPLC-HRMS-based metabolomic approach to analyze the secondary metabolites of wild and cultivated American ginsengs, and found significant differences in ginsenoside profiles between the two. Wild American ginsengs had more abundant and diverse octillol-type ginsenosides, while cultivated American ginsengs had a wider distribution of protopanaxadiol and oleanolic acid-type ginsenosides. The results suggested that the in-house metabolite library and UHPLC-HRMS were effective for identifying characteristic components for distinguishing wild and cultivated American ginseng.
Article
Agriculture, Multidisciplinary
Zhuohong Xie, Yanfang Li, Zhihao Liu, Melody Zeng, Jeffrey C. Moore, Boyan Gao, Xianli Wu, Jianghao Sun, Thomas T. Y. Wang, Pamela Pehrsson, Xiaohua He, Liangli Lucy Yu
Summary: In this study, the bioactives in cinnamon water and ethanol extracts were identified, and it was found that they can suppress the binding of SARS-CoV-2 spike protein to ACE2, reduce ACE2 availability, and scavenge free radicals. Furthermore, new compounds were discovered in cinnamon.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Agriculture, Multidisciplinary
Boyan Gao, Lin Zhu, Zhihao Liu, Yanfang Li, Xiaohua He, Xianli Wu, Pamela Pehrsson, Jianghao Sun, Zhuohong Xie, Margaret Slavin, Liangli Lucy Yu
Summary: This study examined the chemical compositions of water and ethanol extracts of honeysuckle, as well as their potential in inhibiting SARS-CoV-2 spike protein binding to ACE2, suppressing ACE2 activity, and scavenging reactive free radicals. The results showed that both extracts inhibited the binding of SARS-CoV-2 spike protein to ACE2 and ACE2 activity. The water extract had stronger inhibitory effects on ACE2 activity and higher scavenging activities against free radicals compared to the ethanol extract. These findings suggest that honeysuckle may reduce the risk of SARS-CoV-2 infection and severe COVID-19 symptoms.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Plant Sciences
Matthew L. Fabian, Chong Zhang, Jianghao Sun, Neil P. Price, Pei Chen, Christopher R. Clarke, Richard W. Jones, John R. Stommel
Summary: Tomatoes with enhanced anthracnose resistance have higher levels of steroidal glycoalkaloids (SGAs) in their fruit, which can inhibit the development of anthracnose and enhance tomato's resistance. This research provides significant insights into the defense mechanism of tomatoes against anthracnose.
JOURNAL OF EXPERIMENTAL BOTANY
(2023)
Article
Biochemistry & Molecular Biology
Fakir Shahidullah Tareq, Raghavendhar R. Kotha, Savithiry Natarajan, Jianghao Sun, Devanand L. Luthria
Summary: The differential metabolite profiles of wild and cultivated soybeans were compared using untargeted metabolomics. Methanol and water extracts of soybean seeds were analyzed by UHPLC-HRMS, resulting in the identification of 98 metabolites. The metabolite profile was significantly affected by the extraction solvent polarity, and wild and cultivated soybean cultivars showed clear differences. Key metabolites differentiating wild and cultivated soybeans were isoflavonoids, free amino acids, and fatty acids. This metabolic information has implications for the development of improved soybean varieties.
Article
Food Science & Technology
Uyory Choe, Yanfang Li, Zhihao Liu, Yuanhang Yao, Xiaohua He, Jianghao Sun, Xianli Wu, Pamela Pehrsson, Yaqiong Zhang, Boyan Gao, Thomas T. Y. Wang, Liangli Lucy Yu
Summary: This study evaluates dill's potential in preventing SARS-CoV-2 infiltration and alleviating COVID-19 symptoms. The results show that dill extracts have the ability to inhibit the interaction between SARS-CoV-2 spike protein and ACE2 receptor, as well as ACE2 enzyme activity. Additionally, dill exhibits high total phenolic content and free radical scavenging capacity.
ACS FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Yanfang Li, Bin Zhou, Zi Teng, Mengliang Zhang, Liangli Yu, Yaguang Luo, Pei Chen, Jianghao Sun
Summary: The fast-growing field of controlled environment agriculture (CEA) provides an opportunity for targeted improvement in bioactive compounds in fresh produce. This study used Brassica microgreens as model plants to evaluate CEA conditions. A rapid analytical strategy using metabolomic analysis and chemometrics was developed to differentiate microgreens grown under different CEA conditions. The method successfully identified marker compounds and may serve as a scientific foundation for optimizing CEA conditions.
JOURNAL OF AGRICULTURE AND FOOD RESEARCH
(2023)
Article
Agriculture, Multidisciplinary
Yuanhang Yao, Monica Whent, Yanfang Li, Zhihao Liu, Pamela Pehrsson, Jianghao Sun, Pei Chen, Dejian Huang, Thomas T. Y. Wang, Xianli Wu, Liangli Yu
Summary: In this study, water and ethanol extracts of dried thyme were analyzed for their chemical composition and their effects on the SARS-CoV-2 spike protein-ACE2 interaction, ACE2 activity, and free radical scavenging capacity. The results showed that thyme extracts inhibited the spike protein-ACE2 interaction, inhibited ACE2 activity, and exhibited free radical scavenging capacity. The findings suggest that thyme extract could potentially be used to prevent SARS-CoV-2 infection and mitigate the complications from the infection.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Food Science & Technology
Ping Geng, Sharon Hooper, Jianghao Sun, Pei Chen, Karen Cichy, James M. Harnly
Summary: The study analyzed the differences in secondary metabolites between pasta made from different types of beans and wheat, showing that processing and cooking did not significantly contribute to these differences. Factorial multivariate analysis of variance (MANOVA) was used to determine the effects of genotype of bean, cooking status of pasta, and processing conditions on metabolites profiles.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Food Science & Technology
Zhihao Liu, Jenna Shi, Jiawei Wan, Quynchi Pham, Zhi Zhang, Jianghao Sun, Liangli Yu, Yaguang Luo, Thomas T. Y. Wang, Pei Chen
Summary: This study provides the first report on the polyphenol and glucosinolate composition of kale and broccoli microgreens grown in different environments. The results showed a clear variation in secondary metabolites between growth chamber and windowsill conditions, suggesting that the growing environment affects the composition of health-beneficial components in vegetables.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Food Science & Technology
Yanfang Li, Katherine Wu, Zhihao Liu, Xiaohua He, Jianghao Sun, Melody Zeng, Seong-Ho Lee, Thomas T. Y. Wang, Boyan Gao, Zhuohong Xie, Cheng- Wei, Liangli Lucy Yu
Summary: This study investigated the effects of different thermal treatments (steaming and baking) on the chemical compositions, antioxidant components, and antioxidant properties of tomato seeds. The results showed that thermal treatments can alter the phenolic compositions of tomato seeds and steaming can effectively enhance their antioxidant activities.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Food Science & Technology
Zhihao Liu, Zi Teng, Daniel J. Pearlstein, Pei Chen, Liangli Yu, Bin Zhou, Yaguang Luo, Jianghao Sun
Summary: This research investigated the effect of LED light wavelengths on the phytochemical profiles of Ruby Streaks mustard microgreens, and found that red and magenta light promoted the accumulation of anthocyanins and aliphatic GLs, while blue light was dominant in the accumulation of non-anthocyanin phenolics.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
