Sirtuins in dermatology: applications for future research and therapeutics

Oncogenic viral protein HPV E7 up-regulates the SIRT1 longevity protein in human cervical cancer cells

(2016) Simon J. Allison et al.   Aging-US

Structural Basis for Sirtuin Activity and Inhibition

(2012) Hua Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oral Nicotinamide Reduces Actinic Keratoses in Phase II Double-Blinded Randomized Controlled Trials

(2012) Devita Surjana et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Effects of Niacin Restriction on Sirtuin and PARP Responses to Photodamage in Human Skin

(2012) Claudia A. Benavente et al.   PLoS One

Effects of SIRT6 silencing on collagen metabolism in human dermal fibroblasts

(2011) Yang Baohua et al.   CELL BIOLOGY INTERNATIONAL

Cancer Cell Survival Following DNA Damage-mediated Premature Senescence Is Regulated by Mammalian Target of Rapamycin (mTOR)-dependent Inhibition of Sirtuin 1

(2011) Jung Ho Back et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Deacetylates the DNA Methyltransferase 1 (DNMT1) Protein and Alters Its Activities

(2011) L. Peng et al.   MOLECULAR AND CELLULAR BIOLOGY

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

Activation of Sirt1 by Resveratrol Inhibits TNF-α Induced Inflammation in Fibroblasts

(2011) Xiaoxia Zhu et al.   PLoS One

Aging and disease: connections to sirtuins

(2010) Gizem Donmez et al.   AGING CELL

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Genetics of keloid scarring

(2010) Barbara Shih et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

Incidence Estimate of Nonmelanoma Skin Cancer in the United States, 2006

(2010) Howard W. Rogers et al.   ARCHIVES OF DERMATOLOGY

Sirtuin activators: Designing molecules to extend life span

(2010) Antoni Camins et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Negative regulation of stress-induced matrix metalloproteinase-9 by Sirt1 in skin tissue

(2010) Ji-Seon Lee et al.   EXPERIMENTAL DERMATOLOGY

Germline Epigenetic Regulation of KILLIN in Cowden and Cowden-like Syndrome

(2010) Kristi L. Bennett   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

SIRT1 Regulates Autoacetylation and Histone Acetyltransferase Activity of TIP60

(2010) Jiadong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Regulates UV-Induced DNA Repair through Deacetylating XPA

(2010) Wei Fan et al.   MOLECULAR CELL

A novel pathway regulates memory and plasticity via SIRT1 and miR-134

(2010) Jun Gao et al.   NATURE

Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy

(2010) Hugo Wurtele et al.   NATURE MEDICINE

Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C

(2010) M. Ming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging and cancer cell biology, 2009

(2009) Judith Campisi et al.   AGING CELL

Telomere shortening may be associated with human keloids

(2009) Bruna De Felice et al.   BMC Medical Genetics

SIRT6 Links Histone H3 Lysine 9 Deacetylation to NF-κB-Dependent Gene Expression and Organismal Life Span

(2009) Tiara L.A. Kawahara et al.   CELL

Sirtuin inhibitors

(2009) Francisco J Alcaín et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Sirtuin activators

(2009) Francisco J Alcaín et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A protein deacetylase SIRT1 is a negative regulator of metalloproteinase-9

(2009) Yuji Nakamaru et al.   FASEB JOURNAL

NF-κB Signaling in the Aging Process

(2009) Antero Salminen et al.   JOURNAL OF CLINICAL IMMUNOLOGY

B-Cell-Directed Therapy for Inflammatory Skin Diseases

(2009) Angela Nagel et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1

(2009) S. B. Rajamohan et al.   MOLECULAR AND CELLULAR BIOLOGY

Intracellular NAD levels regulate tumor necrosis factor protein synthesis in a sirtuin-dependent manner

(2009) Frédéric Van Gool et al.   NATURE MEDICINE

Telomere Diseases

(2009) Rodrigo T. Calado et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aberrant expression pattern of histone acetylation modifiers and mitigation of lupus by SIRT1-siRNA in MRL/lprmice

(2009) N Hu et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Sirt2 interacts with 14-3-3 β/γ and down-regulates the activity of p53

(2008) Yun-Hye Jin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of transcriptional activity of c-JUN by SIRT1

(2008) Zhanguo Gao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Discovery, In Vivo Activity, and Mechanism of Action of a Small-Molecule p53 Activator

(2008) Sonia Lain et al.   CANCER CELL

Mitochondria—A Nexus for Aging, Calorie Restriction, and Sirtuins?

(2008) Leonard Guarente   CELL

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

sirt1-null mice develop an autoimmune-like condition

(2008) Jedon Sequeira et al.   EXPERIMENTAL CELL RESEARCH

Chromatin-modifying enzymes as therapeutic targets – Part 1

(2008) Brian R Keppler et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

SIRT1 confers protection against UVB- and H2O2-induced cell death via modulation of p53 and JNK in cultured skin keratinocytes

(2008) Cong Cao et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

SIRT1 Promotes Differentiation of Normal Human Keratinocytes

(2008) Gil Blander et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Substrates and Regulation Mechanisms for the Human Mitochondrial Sirtuins Sirt3 and Sirt5

(2008) Christine Schlicker et al.   JOURNAL OF MOLECULAR BIOLOGY

Guidelines of care for the management of psoriasis and psoriatic arthritis

(2008) Alan Menter et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

SIRT3 Is a Stress-Responsive Deacetylase in Cardiomyocytes That Protects Cells from Stress-Mediated Cell Death by Deacetylation of Ku70

(2008) N. R. Sundaresan et al.   MOLECULAR AND CELLULAR BIOLOGY

SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin

(2008) Eriko Michishita et al.   NATURE