Article
Immunology
Gaia Scabia, Giovanna Testa, Manuela Scali, Serena Del Turco, Genni Desiato, Nicoletta Berardi, Alessandro Sale, Michela Matteoli, Lamberto Maffei, Margherita Maffei, Marco Mainardi
Summary: Environmental enrichment can decrease circulating levels of ccl11 in elderly individuals and aged mice, leading to improvements in memory retention, hippocampal neurogenesis, and microglial activation. This suggests that a decrease in ccl11 concentration may be a key mediator of the enhanced hippocampal function resulting from exposure to environmental enrichment.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Psychology, Clinical
Afra van der Markt, Ursula Klumpers, Annemiek Dols, Nicole Korten, Marco P. Boks, Roel A. Ophoff, Aartjan Beekman, Ralph Kupka, Neeltje E. M. van Haren, Hugo Schnack
Summary: This study investigates the association between brain structures and illness progression in bipolar disorder (BD) and explores the potential of brain-predicted age difference (brain-PAD) as a biomarker for BD staging. The results suggest that higher brain-PAD is associated with impaired inter-episodic functioning, but this association loses significance after considering confounding factors such as lithium-use and comorbid anxiety disorders. There is no significant association between global and (sub)cortical brain measures and illness stages.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Immunology
Patricia Lavandoski, Vinicius Pierdona, Rafael Moura Maurmann, Lucas Kich Grun, Fatima T. C. R. Guma, Florencia Maria Barbe-Tuana
Summary: This study provides insights into the mechanisms underlying the pro-aging effects of CCL11 in the lungs of asthmatic patients. Understanding the role of CCL11 in senescence development may have important implications for the treatment of age-related lung diseases, such as asthma.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Reproductive Biology
Leszek Krakowski, Michal Wieszczeczynski, Jacek Furmaga, Izabela Krakowska, Grzegorz Opielak, Piotr Brodzki, Tomasz Piech, Magdalena Grodzka, Dorota Domagala, Olga Furmaga, Christos Rokos
Summary: Prostatic hyperplasia (PH) is a common reproductive disorder in dogs. The use of biomarkers for diagnosing PH in dogs has limited effectiveness, as demonstrated by the study's findings on CCL11 and TGF-beta 1 markers.
Article
Biochemistry & Molecular Biology
Dina Polosukhina, Kshipra Singh, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Dana M. Hardbower, M. Blanca Piazuelo, M. Kay Washington, Alain P. Gobert, Keith T. Wilson, Lori A. Coburn
Summary: The study found that CCL11 is involved in the pathogenesis of DSS-induced colitis and contributes to colon tumorigenesis. Mice lacking CCL11 exhibited less intestinal damage and reduced cancer development in experiments, indicating the important role of CCL11 in the development of colitis and colon cancer.
Article
Clinical Neurology
Monica Macellaro, Nicolaja Girone, Laura Cremaschi, Monica Bosi, Bruno Mario Cesana, Federico Ambrogi, Valentina Caricasole, Federica Giorgetti, Terence A. Ketter, Bernardo Dell'Osso
Summary: This study retrospectively evaluated the applicability and progression of four staging models in a sample of 100 bipolar disorder patients. The results showed a pattern of stage worsening for each model, with a significant increase at each time point. Patients with lower education level, younger age at first episode, shorter illness duration, and shorter duration of untreated illness showed greater stage increases. Lower stage values were associated with certain characteristics, such as BD II, no psychiatric hospitalization, depressive onset, and few lifetime episodes.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Geriatrics & Gerontology
Afra van der Markt, Alexandra J. M. Beunders, Nicole C. M. Korten, Sigfried N. T. M. Schouws, Aartjan T. F. Beekman, Ralph W. Kupka, Ursula Klumpers, Annemiek Dols
Summary: This study examined the validity and applicability of two staging models in older-age bipolar disorder (OABD) and their associations with clinical markers. The findings showed low concordance between the two models, with model A significantly associated with childhood abuse, illness duration, and episode density, while model B showed no significant associations with any markers.
INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
(2022)
Article
Psychiatry
Richie Jeremian, Alexandra Malinowski, Zanib Chaudhary, Anil Srivastava, Jessica Qian, Clement Zai, Christopher Adanty, Corinne E. Fischer, Amer M. Burhan, James L. Kennedy, Carol Borlido, Philip Gerretsen, Ariel Graff, Gary Remington, John B. Vincent, John S. Strauss, Vincenzo De Luca
Summary: This study found significant epigenetic age acceleration in individuals with bipolar disorder compared to healthy controls, suggesting potential premature aging phenotype associated with the disease. Further research is needed to explore the precise link between epigenetic age, symptomatology, and disease progression.
PSYCHIATRY RESEARCH
(2022)
Article
Psychiatry
Hyeyoung Kim, Sang Jin Rhee, Hyunju Lee, Dohyun Han, Tae Young Lee, Minah Kim, Eun Young Kim, Jun Soo Kwon, Hyunsuk Shin, Hyeyoon Kim, Yong Min Ahn, Kyooseob Ha
Summary: High-throughput proteomic technologies were used to identify dysregulated proteins in the plasma of patients with major depressive disorder (MDD) and bipolar disorder (BD). Several proteins were found to be altered in both disorders, with higher fold changes observed in MDD patients. These findings may aid in identifying candidate biomarkers for mood disorders.
PSYCHIATRY RESEARCH
(2021)
Review
Psychiatry
Sonya Grewal, Stuart McKinlay, Flavio Kapczinski, Bianca Pfaffenseller, Bianca Wollenhaupt-Aguiar
Summary: This systematic review examines the biological markers associated with illness progression in bipolar disorder. It finds that increased ventricular size and reduction of grey matter volume are common brain changes associated with the progression of the disorder. In addition, peripheral inflammatory markers also play a role in this process.
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Article
Clinical Neurology
Laura Montejo, Brisa Sole, Esther Jimenez, Roger Borras, Derek Clougher, Maria Reinares, Maria J. Portella, Anabel Martinez-Aran, Eduard Vieta, Caterina del Mar Bonnin, Carla Torrent
Summary: This study describes the cognitive performance in different age groups of individuals with bipolar disorder. The results demonstrate that older age is associated with a selective cognitive decline in the attentional domain in individuals with bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Biochemistry & Molecular Biology
Shouheng Lin, Xuchao Zhang, Guohua Huang, Lin Cheng, Jiang Lv, Diwei Zheng, Simiao Lin, Suna Wang, Qiting Wu, Youguo Long, Baiheng Li, Wei Wei, Pentao Liu, Duanqing Pei, Yangqiu Li, Zhesheng Wen, Shuzhong Cui, Peng Li, Xiaofang Sun, Yilong Wu, Yao Yao
Summary: This study revealed that intratumoral MDSC infiltration is associated with NSCLC progression and promotes metastasis through producing CCL11, which activates ERK and AKT signaling pathways and induces EMT. High expression of CCL11 is correlated with poor prognosis in lung cancer and other cancer types.
Article
Geriatrics & Gerontology
Nikolas Wada, Elizabeth C. Breen, Wendy S. Post, Valentina Stosor, Bernard J. Macatangay, Joseph B. Margolick
Summary: This study observed higher concentrations of CRP in men living with HIV compared to HIV-negative men at different ages, and men with detectable HIV RNA showed faster increases in CRP with age.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
(2022)
Article
Clinical Neurology
Adrian Andrzej Chrobak, Zbigniew Soltys, Dominika Dudek, Marcin Siwek
Summary: The aim of this study was to evaluate the effect of BD type, stage, and the history of psychotic symptoms (HoPS) on the severity of neurological and cerebellar soft signs (NSS and CSS). The results showed that staging was closely related to CSS and NSS scores, while the history of psychotic symptoms was associated with oculomotor deficits. The study found that late-stage BD had more severe CSS and NSS than the control group, while early-stage BD only showed differences in posture and gait disturbances compared to the control group.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
(2023)
Article
Multidisciplinary Sciences
Kuninobu Wakabayashi, Takeo Isozaki, Yumi Tsubokura, Sayaka Fukuse, Tsuyoshi Kasama
Summary: The study reveals that in rheumatoid arthritis, CCL11 mediates leukocyte migration through CCR3, impacting disease progression. Experimental findings show elevated levels of CCL11 and CCR3 expression in RA patients, with inducible expression by stimulants like TNF-alpha.
SCIENTIFIC REPORTS
(2021)
Article
Neurosciences
Mariele Lino Silva, Lais Bhering Martins, Luana Caroline dos Santos, Gilberto Simeone Henriques, Antonio Lucio Teixeira, Ana Maria dos Santos Rodrigues, Adaliene Versiani Matos Ferreira
Summary: This study suggests that patients with migraine have lower plasma levels of minerals and lower dietary intake of minerals compared to individuals without migraine. It highlights the importance of dietary intervention to ensure adequate mineral intake as a therapeutic strategy for migraine.
NUTRITIONAL NEUROSCIENCE
(2023)
Article
Clinical Neurology
Mario A. Parra, Paulina Orellana, Tomas Leon, Cabello G. Victoria, Fernando Henriquez, Rodrigo Gomez, Constanza Avalos, Andres Damian, Andrea Slachevsky, Agustin Ibanez, Henrik Zetterberg, Betty M. Tijms, Jennifer S. Yokoyama, Stefanie D. Pina-Escudero, J. Nicholas Cochran, Diana L. Matallana, Daisy Acosta, Ricardo Allegri, Bianca P. Arias-Suarez, Bernardo Barra, Maria Isabel Behrens, SoniaM. D. Brucki, Geraldo Busatto, Paulo Caramelli, Sheila Castro-Suarez, Valeria Contreras, Nilton Custodio, Sergio Dansilio, Myriam De la Cruz-Puebla, Leonardo Cruz de Souza, Monica M. Diaz, Lissette Duque, Gonzalo A. Farias, Sergio T. Ferreira, Nahuel Magrath Guimet, Ana Kmaid, David Lira, Francisco Lopera, Beatriz Mar Meza, Eliane C. Miotto, Ricardo Nitrini, Alberto Nunez, Santiago O'Neill, John Ochoa, Maritza Pintado-Caipa, Elisa de Paula Franca Resende, Shannon Risacher, Luz Angela Rojas, Valentina Sabaj, Lucas Schilling, Allis F. Sellek, Ana Sosa, Leonel T. Takada, Antonio L. Teixeira, Martha Unaucho-Pilalumbo, Claudia Duran-Aniotz
Summary: Limited knowledge and funding, as well as inadequate infrastructure, present significant barriers to dementia biomarker research in Latin American and Caribbean countries. However, the region shows great potential for advancements in this field.
ALZHEIMERS & DEMENTIA
(2023)
Review
Clinical Neurology
Samantha E. Russell, Anna L. Wrobel, David Skvarc, Bianca E. Kavanagh, Melanie M. Ashton, Olivia M. Dean, Michael Berk, Alyna Turner
Summary: Comorbid PTSD may affect the pharmacologic treatment outcomes for adults with bipolar disorder. Further research is needed to inform pharmacotherapy selection and guidelines for individuals with comorbid bipolar disorder and PTSD.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Psychiatry
Anna L. Wrobel, Sue M. Cotton, Anuradhi Jayasinghe, Claudia Diaz-Byrd, Anastasia K. Yocum, Alyna Turner, Olivia M. Dean, Samantha E. Russell, Elizabeth R. Duval, Tobin J. Ehrlich, David F. Marshall, Michael Berk, Melvin G. McInnis
Summary: This study compared the networks of depressive symptoms among individuals with bipolar disorder with and without a history of childhood trauma. It found that depressed mood consistently emerged as a central symptom regardless of childhood trauma history. Among individuals with a history of childhood trauma, feelings of worthlessness emerged as a key symptom in the network of self-reported depressive symptoms. These findings provide insights into the impact of childhood trauma on depressive symptoms in bipolar disorder.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Clinical Neurology
Marco Solmi, Trevor Thompson, Andres Estrade, Agorastos Agorastos, Joaquim Radua, Samuele Cortese, Elena Dragioti, Friedrich Leisch, Davy Vancampfort, Lau Caspar Thygesen, Harald Aschauer, Monika Schloegelhofer, Elena Aschauer, Andres Schneeberger, Christian G. Huber, Gregor Hasler, Philippe Conus, Kim Q. Do Cuenod, Roland von Kaenel, Gonzalo Arrondo, Paolo Fusar-Poli, Philip Gorwood, Pierre-Michel Llorca, Marie-Odile Krebs, Elisabetta Scanferla, Taishiro Kishimoto, Golam Rabbani, Karolina Skonieczna-Zydecka, Paolo Brambilla, Angela Favaro, Akihiro Takamiya, Leonardo Zoccante, Marco Colizzi, Julie Bourgin, Karol Kaminski, Maryam Moghadasin, Soraya Seedat, Evan Matthews, John Wells, Emilia Vassilopoulou, Ary Gadelha, Kuan-Pin Su, Jun Soo Kwon, Minah Kim, Tae Young Lee, Oleg Papsuev, Denisa Mankova, Andrea Boscutti, Cristiano Gerunda, Diego Saccon, Elena Righi, Francesco Monaco, Giovanni Croatto, Guido Cereda, Jacopo Demurtas, Natascia Brondino, Nicola Veronese, Paolo Enrico, Pierluigi Politi, Valentina Ciappolino, Andrea Pfennig, Andreas Bechdolf, Andreas Meyer-Lindenberg, Kai G. Kahl, Katharina Domschke, Michael Bauer, Nikolaos Koutsouleris, Sibylle Winter, Stefan Borgwardt, Istvan Bitter, Judit Balazs, Pal Czobor, Zsolt Unoka, Dimitris Mavridis, Konstantinos Tsamakis, Vasilios P. Bozikas, Chavit Tunvirachaisakul, Michael Maes, Teerayuth Rungnirundorn, Thitiporn Supasitthumrong, Ariful Haque, Andre R. Brunoni, Carlos Gustavo Costardi, Felipe Barreto Schuch, Guilherme Polanczyk, Jhoanne Merlyn Luiz, Lais Fonseca, Luana V. Aparicio, Samira S. Valvassori, Merete Nordentoft, Per Vendsborg, Sofie Have Hoffmann, Jihed Sehli, Norman Sartorius, Sabina Heuss, Daniel Guinart, Jane Hamilton, John Kane, Jose Rubio, Michael Sand, Ai Koyanagi, Aleix Solanes, Alvaro Andreu-Bernabeu, Antonia San Jose Caceres, Celso Arango, Covadonga M. Diaz-Caneja, Diego Hidalgo-Mazzei, Eduard Vieta, Javier Gonzalez-Penas, Lydia Fortea, Mara Parellada, Miquel A. Fullana, Norma Verdolini, Eva Andrlikova, Karolina Janku, Mark John Millan, Mihaela Honciuc, Anna Moniuszko-Malinowska, Igor Loniewski, Jerzy Samochowiec, Lukasz Kiszkiel, Maria Marlicz, Pawel Sowa, Wojciech Marlicz, Georgina Spies, Brendon Stubbs, Joseph Firth, Sarah Sullivan, Asli Enez Darcin, Hatice Aksu, Nesrin Dilbaz, Onur Noyan, Momoko Kitazawa, Shunya Kurokawa, Yuki Tazawa, Alejandro Anselmi, Cecilia Cracco, Ana Ines Machado, Natalia Estrade, Diego De Leo, Jackie Curtis, Michael Berk, Philip Ward, Scott Teasdale, Simon Rosenbaum, Wolfgang Marx, Adrian Vasile Horodnic, Liviu Oprea, Ovidiu Alexinschi, Petru Ifteni, Serban Turliuc, Tudor Ciuhodaru, Alexandra Bolos, Valentin Matei, Dorien H. Nieman, Iris Sommer, Jim van Os, Therese van Amelsvoort, Ching-Fang Sun, Ta-wei Guu, Can Jiao, Jieting Zhang, Jialin Fan, Liye Zou, Xin Yu, Xinli Chi, Philippe de Timary, Ruud van Winkel, Bernardo Ng, Edilberto Pena, Ramon Arellano, Raquel Roman, Thelma Sanchez, Larisa Movina, Pedro Morgado, Sofia Brissos, Oleg Aizberg, Anna Mosina, Damir Krinitski, James Mugisha, Dena Sadeghi-Bahmani, Farshad Sheybani, Masoud Sadeghi, Samira Hadi, Serge Brand, Antonia Errazuriz, Nicolas Crossley, Dragana Ignjatovic Ristic, Carlos Lopez-Jaramillo, Dimitris Efthymiou, Praveenlal Kuttichira, Roy Abraham Kallivayalil, Afzal Javed, Muhammad Iqbal Afridi, Bawo James, Omonefe Joy Seb-Akahomen, Jess Fiedorowicz, Andre F. Carvalho, Jeff Daskalakis, Lakshmi N. Yatham, Lin Yang, Tarek Okasha, Aicha Dahdouh, Bjoern Gerdle, Jari Tiihonen, Jae Il Shin, Jinhee Lee, Ahmed Mhalla, Lotfi Gaha, Takoua Brahim, Kuanysh Altynbekov, Nikolay Negay, Saltanat Nurmagambetova, Yasser Abu Jamei, Mark Weiser, Christoph U. Correll
Summary: The COH-FIT survey is a valid instrument to measure global mental health during the COVID-19 pandemic. The study confirmed the validity of COH-FIT items and the internal reliability of the co-primary outcome, the P-score. The survey has been translated into 30 languages and measures various mental health symptoms and factors.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Review
Biochemistry & Molecular Biology
Bruna Panizzutti, David Skvarc, Sylvia Lin, Sarah Croce, Alcy Meehan, Chiara Cristina Bortolasci, Wolfgang Marx, Adam J. Walker, Kyoko Hasebe, Bianca E. Kavanagh, Margaret J. Morris, Mohammadreza Mohebbi, Alyna Turner, Laura Gray, Lesley Berk, Ken Walder, Michael Berk, Olivia M. Dean
Summary: Minocycline has been found to have anti-inflammatory, antioxidant, and anti-apoptotic properties, which has led to a renewed interest in using it as an adjunctive treatment for psychiatric and neurological conditions. A systematic review and meta-analysis of the available data from clinical trials using minocycline was conducted, showing limited and difficult to interpret results for most conditions, but suggesting an overall benefit for using minocycline as an adjunctive treatment for schizophrenia.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Editorial Material
Psychiatry
Michael Berk
Review
Psychiatry
Daniel M. Dietch, Jess Kerr-Gaffney, Meghan Hockey, Wolfgang Marx, Anu Ruusunen, Allan H. Young, Michael Berk, Valeria Mondelli
Summary: This study conducted a systematic review and narrative synthesis of low carbohydrate and ketogenic diets (LC/KD) in adults with mood and anxiety disorders. Although there is no high-quality evidence of LC/KD efficacy in mood or anxiety disorders, several uncontrolled studies suggest possible beneficial effects. Robust studies are now needed to demonstrate efficacy, identify clinical groups who may benefit, and characterize adverse effects and the risk of relapse after diet discontinuation.
Article
Pharmacology & Pharmacy
Ivana Bojanic, Ottar Bjerkeset, Lana J. Williams, Michael Berk, Johan Hakon Bjorngaard, Erik R. Sund, Hege Sletvold
Summary: This study examined the relationship between the use of cardiovascular drugs and metformin and the risk of initiating antidepressant use. The findings suggest that ARBs and CCBs as monotherapy may reduce the risk, while ASA or statins as polytherapy may also decrease the risk. However, the limitations in the study design may introduce bias.
PHARMACOLOGY RESEARCH & PERSPECTIVES
(2023)
Article
Psychiatry
James McLure, Tari Forrester-Bowling, Anna Peeters, Michael Berk, Steven Moylan, Renae Carolin
Summary: Objective Person-centred growth-oriented language and care are vital in mental health care. The testimonies in the Final Report of the Royal Commission into Victoria's Mental Health System highlight the need for a compassionate and hope-filled system, which can be achieved through person-centred growth-oriented language. There is a lack of understanding about the process and language involved in individuals' mental health growth. Recovery should not just mean returning to baseline, but should also involve daily personal growth and improvement towards mental health.
AUSTRALASIAN PSYCHIATRY
(2023)
Article
Psychiatry
Dhamidhu Eratne, Matthew Kang, Charles Malpas, Steve Simpson-Yap, Courtney Lewis, Christa Dang, Jasleen Grewal, Amy Coe, Hannah Dobson, Michael Keem, Wei-Hsuan Chiu, Tomas Kalincik, Suyi Ooi, David Darby, Amy Brodtmann, Oskar Hansson, Shorena Janelidze, Kaj Blennow, Henrik Zetterberg, Adam Walker, Olivia Dean, Michael Berk, Cassandra Wannan, Christos Pantelis, Samantha M. Loi, Mark Walterfang, Samuel F. Berkovic, Alexander F. Santillo, Dennis Velakoulis, MiND Study Grp
Summary: This study investigated the diagnostic utility of blood biomarkers of neuronal injury, specifically neurofilament light, in differentiating neurodegenerative disorders from primary psychiatric disorders (PPD). The results showed that neurofilament light could accurately distinguish behavioral variant frontotemporal dementia (bvFTD) from PPD. Large reference data sets and models were used to interpret individual levels, and slightly higher neurofilament light levels were found in bipolar affective disorder (BPAD) compared to controls and treatment-resistant schizophrenia (TRS).
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Article
Clinical Neurology
Tobin J. Ehrlich, Hanjoo Kim, Kelly A. Ryan, Scott A. Langenecker, Elizabeth R. Duval, Anastasia K. Yocum, Claudia Diaz-Byrd, Anna L. Wrobel, Olivia M. Dean, Sue M. Cotton, Michael Berk, Melvin G. McInnis, David F. Marshall
Summary: This study evaluated the relationship between childhood trauma and cognition in individuals diagnosed with bipolar disorder. It found that higher childhood trauma was associated with worse memory functioning in bipolar disorder patients. The study emphasizes the importance of understanding the long-term cognitive outcomes of childhood trauma in bipolar disorder.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Susan L. Rossell, Ayla Baratchu, Clinton Schultz, Eileen Mcdonald, Christopher G. Davey, Adrienne O'Neil, Philip J. Batterham, Preet Kaur, Angela Markus, Michael Berk
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY
(2023)
Review
Nutrition & Dietetics
Hajara Aslam, Mojtaba Lotfaliany, Daniel So, Kirsten Berding, Michael Berk, Tetyana Rocks, Meghan Hockey, Felice N. Jacka, Wolfgang Marx, John F. Cryan, Heidi M. Staudacher
Summary: This study conducted a systematic literature review and meta-analysis to explore the effects of dietary fibers on depressive and anxiety outcomes. The results showed a negative correlation between fiber intake and depressive and anxiety outcomes in observational studies. However, current randomized controlled trials did not support the use of fiber supplementation for improving depressive or anxiety outcomes. Further research, including clinical trials in specific populations and using a wider range of fiber types, is needed.
Article
Psychiatry
Anna Gimenez-Palomo, Mariona Guitart-Mampel, Ana Meseguer, Roger Borras, Francesc Josep Garcia-Garcia, Esther Tobias, Laura Valls, Xavier Alsina-Restoy, Gemma Roque, Ester Sanchez, Josep Roca, Gerard Anmella, Marc Valenti, Lorenzo Bracco, Helena Andreu, Sergi Salmeron, Lluc Colomer, Joaquim Radua, Norma Verdolini, Michael Berk, Eduard Vieta, Gloria Garrabou, Isabella Pacchiarotti
Summary: This study investigated mitochondrial respiration in patients with BD during mood episodes and found that there was a significant increase in maximal oxygen consumption capacity after clinical remission. This suggests that bioenergetic and mitochondrial dysregulation may be present in both manic and depressive phases of BD, and could potentially serve as biomarkers for illness activity and clinical response. Further research with larger samples is needed to confirm these findings.
ACTA PSYCHIATRICA SCANDINAVICA
(2023)
Article
Clinical Neurology
Jai Carmichael, Jennie Ponsford, Kate Rachel Gould, Gershon Spitz
Summary: The traditional approaches to measuring depression after traumatic brain injury (TBI) have limitations. This study adopted a symptom-oriented approach and found that post-TBI depression is highly heterogeneous. Different depressive symptoms have distinct associations with personal, injury-related, treatment, and outcome factors.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Xiaoning Sun, Min Chen, Guanghai Wang, Fan Jiang
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Aleksander Kwas
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Josine E. Verhoeven, Laura K. M. Han, Brenda W. J. H. Penninx
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Review
Clinical Neurology
Erin Crowe, Petra K. Staiger, Steven J. Bowe, Imogen Rehm, Richard Moulding, Caitlyn Herrick, David J. Hallford
Summary: This study aimed to integrate the evidence regarding the relationship between emotion regulation difficulties and TTM symptoms, and found that individuals with higher levels of TTM severity appear to exhibit decreased overall emotion regulation abilities and strategies.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Fjolla Berisha, Marjolaine Rivest-Beauregard, Jai Shah, Michelle Lonergan, Alain Brunet
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yi-Tseng Tsai, Tzu-Jung Chuang, Sriyani Padmalatha Konara Mudiyanselage, Han-Chang Ku, Yi-Lin Wu, Chung-Yi Li, Nai-Ying Ko
Summary: Sleep disturbances are associated with higher suicide rates, and this association is independent of depression. Paying attention to sleep disturbances among PLHIV is crucial when monitoring suicidal ideation.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Junyou Chen, Ingrid D. Lui, Yu Cheng Hsu, Paul S. F. Yip
Summary: Despite rapid social changes in Hong Kong, marriage remains a strong protective factor against suicide for both men and women, particularly among younger individuals. Increasing suicide rates among divorced/separated, never-married, or widowed individuals suggest a need for more psychosocial support.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
A. Perry, K. Gordon-Smith, K. J. S. Lewis, A. Di Florio, N. Craddock, L. Jones, I. Jones
Summary: This study found that the experience of losing at least one night of sleep was associated with an increased risk of postpartum psychosis in women with bipolar disorder. Sleep quality in late pregnancy was not associated with postpartum psychosis, and perinatal sleep disruption was not associated with postpartum depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Dear J. Affect Disord, Mark J. Niciu, Robert C. Meisner, Brent R. Carr, Ali A. Farooqui, David Feifel, Adam Kaplin, Paul M. Kim, Christopher D. Schneck, Jennifer L. Vande Voort, Sagar Parikh, E. Jeremy Kendrick
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Tao Wang, Li Yang, Lan Yang, Bao-Peng Liu, Cun-Xian Jia
Summary: This study systematically reviewed the association between psychological pain and suicidality in patients with major depressive disorder (MDD). The results showed that psychological pain was a risk factor for suicidality in MDD patients, especially for those of advancing age. Reducing psychological pain in MDD patients is important for preventing suicidality.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Letter
Clinical Neurology
Juan Carlos Hugues, Abel Nogueira-Lopeza, Maeva Flayellea, Cora von Hammersteind, Joel Billieuxa
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Ogechi Cynthia Onyeka, Samuel D. Spencer, Alison Salloum, Katie Jiannetto, Eric A. Storch
Summary: This study examined the relationship among family accommodation (FA), posttraumatic stress symptoms (PTSS), and functional impairment. The results showed that FA was significantly associated with PTSS and functional impairment. Baseline FA partially mediated the relationship between baseline PTSS and functional impairment. Changes in FA from pre- to post-treatment were associated with relevant outcome variables at post-treatment and 12-month follow-up.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Yumeng Shi, Chao Yu
Summary: This study found a negative correlation between the intake of active microbes in the diet and depression.
JOURNAL OF AFFECTIVE DISORDERS
(2024)
Article
Clinical Neurology
Qiurui Nie, Yu Shen, Mengqin Luo, Zhiyong Sheng, Rui Zhou, Guangmin Li, Wei Huang, Shenjian Chen
Summary: The study assessed the sleep duration, sleep disorders, and trouble sleeping among adults in the United States from 2005 to 2018, revealing a high prevalence of abnormal sleep durations and increasing rates of sleep disorders and trouble sleeping.
JOURNAL OF AFFECTIVE DISORDERS
(2024)