Targeting GluN2B-ContainingN-Methyl-D-aspartate Receptors: Design, Synthesis, and Binding Affinity Evaluation of Novel 3-Substituted Indoles

Synthesis, modelling and biological characterization of 3-substituted-1H-indoles as ligands of GluN2B-containing N-methyl-d-aspartate receptors

(2014) Rosaria Gitto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Indole derivatives as dual-effective agents for the treatment of neurodegenerative diseases: Synthesis, biological evaluation, and molecular modeling studies

(2013) Maria Rosa Buemi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

From NMDA receptor antagonists to discovery of selective σ2 receptor ligands

(2013) Rosaria Gitto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of 3-Acylindoles by Palladium-Catalyzed Acylation of Free (N–H) Indoles with Nitriles

(2013) Tao-Shan Jiang et al.   ORGANIC LETTERS

GluN2A and GluN2B subunit-containing NMDA receptors in hippocampal plasticity

(2013) O. A. Shipton et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Pharmacological blockade of GluN2B-containing NMDA receptors induces antidepressant-like effects lacking psychotomimetic action and neurotoxicity in the perinatal and adult rodent brain

(2013) Juan M. Lima-Ojeda et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Excitotoxicity and stroke: Identifying novel targets for neuroprotection

(2013) Ted Weita Lai et al.   PROGRESS IN NEUROBIOLOGY

Role of nonsynaptic GluN2B-containing NMDA receptors in excitotoxicity: Evidence that fluoxetine selectively inhibits these receptors and may have neuroprotective effects

(2012) E.S. Vizi et al.   BRAIN RESEARCH BULLETIN

Glutamatergic Neurotransmission As Molecular Target of New Anticonvulsants

(2012) Rosaria Gitto et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Excitotoxicity: Bridge to various triggers in neurodegenerative disorders

(2012) Ankita Mehta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Synthesis and Biological Characterization of 3-Substituted 1H-Indoles as Ligands of GluN2B-Containing N-Methyl-d-aspartate Receptors. Part 2

(2012) Rosaria Gitto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel and Simple Methodology for the Synthesis of 3-Acetylindoles and their N-Alkyl Derivatives Using TBAB as Phase Transfer Catalyst

(2012) M. Venkatanarayana et al.   LETTERS IN ORGANIC CHEMISTRY

Molecular basis of NMDA receptor functional diversity

(2011) Pierre Paoletti   EUROPEAN JOURNAL OF NEUROSCIENCE

Synthesis and Biological Characterization of 3-Substituted-1H-indoles as Ligands of GluN2B-ContainingN-Methyl-d-aspartate Receptors

(2011) Rosaria Gitto et al.   JOURNAL OF MEDICINAL CHEMISTRY

Subunit arrangement and phenylethanolamine binding in GluN1/GluN2B NMDA receptors

(2011) Erkan Karakas et al.   NATURE

Overview of glutamatergic neurotransmission in the nervous system

(2011) Mark J. Niciu et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

New chloro,fluorobenzylindole derivatives as integrase strand-transfer inhibitors (INSTIs) and their mode of action

(2010) Stefania Ferro et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Small molecules targeting the interaction between HIV-1 integrase and LEDGF/p75 cofactor

(2010) Laura De Luca et al.   BIOORGANIC & MEDICINAL CHEMISTRY

HIV-1 integrase strand-transfer inhibitors: Design, synthesis and molecular modeling investigation

(2010) Laura De Luca et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Development of 3-substituted-1H-indole derivatives as NR2B/NMDA receptor antagonists

(2009) Rosaria Gitto et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Combined Strategies for the Discovery of Ionotropic Glutamate Receptor Antagonists

(2009) Alba Chimirri et al.   ChemMedChem

Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile

(2008) Rosaria Gitto et al.   ChemMedChem