Carnosine metabolism in diabetes is altered by reactive metabolites

Muscle Histidine-Containing Dipeptides Are Elevated by Glucose Intolerance in Both Rodents and Men

(2015) Sanne Stegen et al.   PLoS One

The antineoplastic effect of carnosine is accompanied by induction of PDK4 and can be mimicked by l-histidine

(2014) Ulrike Letzien et al.   AMINO ACIDS

Daily exercise training protects against albuminuria and angiotensin converting enzyme 2 shedding in db/db diabetic mice

(2014) Hari K Somineni et al.   JOURNAL OF ENDOCRINOLOGY

Dietary Carnosine Prevents Early Atherosclerotic Lesion Formation in Apolipoprotein E–Null Mice

(2013) Oleg A. Barski et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endothelial dysfunction — A major mediator of diabetic vascular disease

(2013) Cristina M. Sena et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Physiology and Pathophysiology of Carnosine

(2013) Alexander A. Boldyrev et al.   PHYSIOLOGICAL REVIEWS

Molecular Identification of Carnosine N-Methyltransferase as Chicken Histamine N-Methyltransferase-Like Protein (HNMT-Like)

(2013) Jakub Drozak et al.   PLoS One

Carnosine enhances diabetic wound healing in the db/db mouse model of type 2 diabetes

(2012) Ishrath Ansurudeen et al.   AMINO ACIDS

Protein carbonylation and metabolic control systems

(2012) Jessica M. Curtis et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Carnosine treatment largely prevents alterations of renal carnosine metabolism in diabetic mice

(2011) Verena Peters et al.   AMINO ACIDS

Tyrosine nitration limits stretch-induced CD40 expression and disconnects CD40 signaling in human endothelial cells

(2011) A. H. Wagner et al.   BLOOD

Endothelial nitric oxide synthase enhancer reduces oxidative stress and restores endothelial function in db/db mice

(2011) Wai San Cheang et al.   CARDIOVASCULAR RESEARCH

Carnosine Prevents Apoptosis of Glomerular Cells and Podocyte Loss in STZ Diabetic Rats

(2011) Eva Riedl et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Oral Carnosine Supplementation Prevents Vascular Damage in Experimental Diabetic Retinopathy

(2011) Frederick Pfister et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Nitric oxide synthase derangements and hypertension in kidney disease

(2011) Chris Baylis   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Role of the Decreased Nitric Oxide Bioavailability in the Vascular Complications of Diabetes Mellitus

(2011) Andi Masha et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Energy metabolism, proteotoxic stress and age-related dysfunction – Protection by carnosine

(2011) Alan R. Hipkiss   MOLECULAR ASPECTS OF MEDICINE

Anserine inhibits carnosine degradation but in human serum carnosinase (CN1) is not correlated with histidine dipeptide concentration

(2010) Verena Peters et al.   CLINICA CHIMICA ACTA

N-Glycosylation of Carnosinase Influences Protein Secretion and Enzyme Activity

(2010) Eva Riedl et al.   DIABETES

Association Between CNDP1 Genotype and Diabetic Nephropathy Is Sex Specific

(2010) A. L. Mooyaart et al.   DIABETES

Histidine and carnosine alleviated hepatic steatosis in mice consumed high saturated fat diet

(2010) Mei-chin Mong et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular Identification of Carnosine Synthase as ATP-grasp Domain-containing Protein 1 (ATPGD1)

(2010) Jakub Drozak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure and Mutational Analysis of Aminoacylhistidine Dipeptidase fromVibrio alginolyticusReveal a New Architecture of M20 Metallopeptidases

(2010) Chin-Yuan Chang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Relevance of allosteric conformations and homocarnosine concentration on carnosinase activity

(2009) Verena Peters et al.   AMINO ACIDS

Design, Synthesis, and Evaluation of Carnosine Derivatives as Selective and Efficient Sequestering Agents of Cytotoxic Reactive Carbonyl Species

(2009) Giulio Vistoli et al.   ChemMedChem

Rules Governing Selective Protein Carbonylation

(2009) Etienne Maisonneuve et al.   PLoS One

Protein S-nitrosylation in health and disease: a current perspective

(2009) Matthew W. Foster et al.   TRENDS IN MOLECULAR MEDICINE

Transition metal ion binding studies of carnosine and histidine: Biologically relevant antioxidants

(2008) Stephanie Velez et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Detection of protein S-nitrosylation with the biotin-switch technique

(2008) Michael T. Forrester et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential neuroprotective effects of carnosine, anserine, andN-acetyl carnosine against permanent focal ischemia

(2008) Jiangyong Min et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Advanced lipid peroxidation end products in oxidative damage to proteins. Potential role in diseases and therapeutic prospects for the inhibitors

(2007) A Negre-Salvayre et al.   BRITISH JOURNAL OF PHARMACOLOGY