Article
Geriatrics & Gerontology
J. P. P. Richie Jr, R. Sinha, Z. Dong, S. N. Nichenametla, G. P. Ables, A. Ciccarella, I. Sinha, A. M. Calcagnotto, V. M. Chinchilli, L. Reinhart, D. Orentreich
Summary: Restricting dietary intake of methionine and cysteine can delay the aging process, improve glucose and fat metabolism, and reduce oxidative stress. This study found that feeding restricted methionine or total sulfur amino acids diets to healthy adults had no adverse effects and significantly improved biomarkers of cardiometabolic disease risk. These findings suggest the potential for further clinical development of this intervention.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Nutrition & Dietetics
Zhen Dong, Xiang Gao, Vernon M. Chinchilli, Raghu Sinha, Joshua Muscat, Renate Winkels, John P. Richie
Summary: The study found that high-SAA diets are associated with increased risk for diabetes mortality, and lowering intake towards Recommended Dietary Allowance levels could lead to reductions in lifetime risk.
EUROPEAN JOURNAL OF NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Julio Jose Jimenez-Alonso, Emilio Guillen-Mancina, Jose Manuel Calderon-Montano, Victor Jimenez-Gonzalez, Patricia Diaz-Ortega, Estefania Burgos-Moron, Miguel Lopez-Lazaro
Summary: Sulfur-containing amino acids methionine (Met), cysteine (Cys), and taurine (Tau) play important roles in cellular functions and metabolism. This study investigates the role of Cys and Tau in the anticancer activity of Met-restricted diets. The results show that diets supplemented with Cys or Tau exhibit marked anticancer activity in animal models of colon cancer, ovarian cancer, and renal cell carcinoma. These findings suggest the potential use of these diets in cancer therapy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Agronomy
Andre Froes de Borja Reis, Luiz H. Moro Rosso, Dan Davidson, Peter Kovacs, Larry C. Purcell, Frederick E. Below, Shaun N. Casteel, Carrie Knott, Hans Kandel, Seth L. Naeve, Walter Carciochi, Willian J. Ross, Vitor Rampazzo Favoretto, Sotirios Archontoulis, Ignacio A. Ciampitti
Summary: This study utilized a meta-analytic model to quantify the effects of sulfur application at different growth stages on soybean yield and seed composition. Findings showed that applying sulfur at sowing can increase seed protein concentration, while sulfur amino acids concentration was not affected by the timing of fertilization. Additionally, soils with specific organic matter content displayed significant responses to sulfur application, while drought-stressed sites did not show significant changes in yield or seed composition due to sulfur fertilization.
EUROPEAN JOURNAL OF AGRONOMY
(2021)
Article
Multidisciplinary Sciences
Ryo Kurosawa, Ryota Sugimoto, Hiroe Imai, Kohei Atsuji, Koji Yamada, Yusuke Kawano, Iwao Ohtsu, Kengo Suzuki
Summary: Spaceflight induces hepatic damage due to oxidative stress, with a decrease in sulfur antioxidants observed in mouse livers after 30 days on the International Space Station. Exposure to 1 g centrifugation partially mitigated the damage, suggesting that a reduction in sulfur-containing compounds contributes to liver damage in spaceflight environments.
SCIENTIFIC REPORTS
(2021)
Article
Cell Biology
Sailendra N. Nichenametla, Dwight A. L. Mattocks, Diana Cooke, Vishal Midya, Virginia L. Malloy, Wilfredo Mansilla, Bente Ovrebo, Cheryl Turner, Nasser E. Bastani, Jitka Sokolova, Marketa Pavlikova, John P. Richie, Anna K. Shoveller, Helga Refsum, Thomas Olsen, Kathrine J. Vinknes, Viktor Kozich, Gene P. Ables
Summary: Decreasing the intake of methionine has significant anti-adiposity effects in rodents but only modest effects in humans. The study found that the anti-adiposity effects of dietary restriction were due to cysteine restriction, which increased serinogenesis and reduced fatty acid reesterification and triglyceride synthesis. This finding may have implications for the treatment of hypertriglyceridemia.
Article
Agriculture, Multidisciplinary
Dana Rushovich, Ray Weil
Summary: Soybean seed sulfur and MET+CYS concentrations exhibit wide variability. Field-scale sulfur application is shown to greatly enhance soybean MET+CYS content, thus improving protein quality.
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE
(2021)
Article
Nutrition & Dietetics
Zhen Dong, John P. Richie, Xiang Gao, Laila Al-Shaar, Sailendra N. Nichenametla, Biyi Shen, David Orentreich
Summary: Excess intake of sulfur amino acids is associated with a higher risk of type 2 diabetes. Dietary patterns low in sulfur amino acids could help prevent type 2 diabetes.
JOURNAL OF NUTRITION
(2022)
Article
Veterinary Sciences
Cristina L. Torres, Vincent C. Biourge, Robert C. Backus
Summary: The study showed that dietary restriction of methionine and cysteine has a greater impact on taurine depletion in large dogs, and blood taurine concentration may not be a sensitive indicator of taurine depletion caused by low intake of bioavailable SAA in dogs.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Review
Chemistry, Analytical
Kaveh Moulaee, Giovanni Neri
Summary: The rapid growth in electrochemistry research in the past decade has led to significant advancements in utilizing electrochemical strategies for evaluating biological substances. This review focuses on recent progress in electrochemical amino acid sensing, highlighting key electroactive amino acids and performance metrics of electrochemical sensors. The discussion also addresses remaining challenges and opportunities for further advancement in amino acid electrochemistry.
Article
Fisheries
Romulo Jordao Neves Aroucha, Felipe Barbosa Ribeiro, Marcos Antonio Delmondes Bomfim, Jefferson Costa de Siqueira, Rafael Silva Marchao, Daphinne Cardoso Nagib do Nascimento
Summary: The study aimed to determine the requirement of digestible methionine plus cystine in the diet for tambaqui. The results showed that increasing the dietary digestible methionine plus cystine level influenced the growth performance of tambaqui. The estimated requirements for weight gain, specific growth rate, and feed conversion ratio were 0.876%, 0.883%, and 0.907% of digestible methionine plus cystine, respectively.
AQUACULTURE REPORTS
(2023)
Article
Fisheries
Nicole Martins, Alexandre F. Diogenes, Rui Magalhaes, Isabel Matas, Aires Oliva-Teles, Helena Peres
Summary: The study demonstrated that dietary taurine levels affect intermediary metabolism, particularly carbohydrate and lipid metabolism, and improve the antioxidant status of European seabass juveniles. Additionally, while CDO expression was detected, European seabass seems unable to regulate its activity, supporting the essentiality of taurine for this species.
Article
Biochemical Research Methods
Hao Yang, Haoyang Zheng, Yue Pan, Weiguo Zhang, Mengjing Yang, Huiling Du, Anan Yu, Ping Li, Xiaoyan Chen, Wei Xie, Kaiming Ren, Ying Zhao, Tianjiao Wang, Xiaoyan He, Zhaoli Zhou
Summary: The study demonstrated that deprivation of methionine and cystine inhibits the growth of A549 cells in vitro but does not have a significant effect in vivo. Deprivation was harmful to xenograft-bearing mice, resulting in weight loss and renal dysfunction. Changes in proteome profile and biological processes upon methionine and cystine deprivation were characterized in a xenograft mouse model.
Article
Clinical Neurology
Kathrine J. Vinknes, Helga Refsum, Cheryl Turner, Kay-Tee Khaw, Nicholas J. Wareham, Nita G. Forouhi, Fumiaki Imamura
Summary: The study found that plasma methionine and the methionine/homocysteine ratio were inversely associated with the risk of cerebrovascular diseases, suggesting that methionine may play a role in preventing cerebrovascular diseases.
Review
Chemistry, Multidisciplinary
Marcus J. C. Long, Kuan-Ting Huang, Yimon Aye
Summary: This tutorial review compares and contrasts the chemical mechanisms of electrophile/oxidant sensing and the molecular mechanisms of signal propagation. It critically analyzes biological systems where these pathways are believed to be present and discusses the implications of the data. Finally, it explores the applications of this knowledge in disease treatment and drug development.
CHEMICAL SOCIETY REVIEWS
(2021)
Review
Immunology
Yongyao Yu, Qingchao Wang, Zhenyu Huang, Liguo Ding, Zhen Xu
FRONTIERS IN IMMUNOLOGY
(2020)
Article
Immunology
Fen Dong, Guang-mei Yin, Kai-feng Meng, Hao-yue Xu, Xia Liu, Qing-chao Wang, Zhen Xu
FRONTIERS IN IMMUNOLOGY
(2020)
Article
Reproductive Biology
Junpeng Yao, Hao Du, Hai Zhou, Xiaoqian Leng, Jinping Wu, Shan He, Jiang Luo, Xufang Liang, Hong Liu, Qingchao Wang, Qiwei Wei, Qingsong Tan
Summary: The ovarian development of Chinese sturgeon is affected by dietary lipid levels, with six key genes playing crucial roles in vitellogenic deposition and hydrolysis.
Article
Fisheries
Zixi Song, Congrui Jiao, Baoyang Chen, Wenyu Xu, Mengya Wang, Jiahong Zou, Weiqi Xu, Zhen Xu, Qingchao Wang
Summary: Supplementation of Acanthopanax senticosus extracts in the diet of yellow catfish significantly improved growth, feed utilization, and survival rate against Edwardsiella ictaluri infection. The extracts also mitigated skin lesions, gill inflammation, and liver vasculitis in the fish, while promoting hepatic apoptosis to prevent further necrosis. These results suggest that the extracts modulate inflammation and apoptosis to protect yellow catfish against bacterial infection.
AQUACULTURE RESEARCH
(2021)
Article
Physiology
Mengya Wang, Wenyu Xu, Jiahong Zou, Shuaitong Li, Zixi Song, Feifei Zheng, Wei Ji, Zhen Xu, Qingchao Wang
Summary: The study found that 400mg/L H2O2 treatment significantly improved loach hatchability and reduced egg mortality, while 200mg/L treatment showed no significant effects. NaCl treatment had no significant impact on loach hatchability or egg mortality. Results indicated a potential role of 400mg/L H2O2 in enhancing antioxidant capacity and immune response in fish larvae through promoting early development.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Congrui Jiao, Jiahong Zou, Zhenwei Chen, Feifei Zheng, Zhen Xu, Yu-Hung Lin, Qingchao Wang
Summary: This study used yellow catfish as a model and found that dietary supplementation of glutamine can effectively improve the immune and antioxidant system in fish, reduce excessive inflammation in the gut and gills, and inhibit fish apoptosis and autophagy during bacterial infection.
Article
Fisheries
Bingchao Wang, Fangzheng Zhu, Zechao Shi, Zhenyu Huang, Ruhan Sun, Qingchao Wang, Ouyang Gang, Wei Ji
Summary: In this study, the mhc IIA and mhc IIB genes of yellow catfish Pelteobagrus fulvidraco were cloned and characterized. Similar gene structure and expression patterns were observed for both mhc IIA and mhc IIB, and they play an important role in the anti-infection process.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Review
Immunology
Zixi Song, Jiahong Zou, Mengya Wang, Zhenwei Chen, Qingchao Wang
Summary: Pyroptosis is a programmed cell death process executed by gasdermin family proteins. In fish, it mainly depends on NLRP3 inflammasome and is influenced by pathogenic microorganism infection and environmental pollutants.
JOURNAL OF INFLAMMATION RESEARCH
(2022)
Article
Fisheries
Shuaitong Li, Jiahong Zou, Xu Wang, Zixi Song, Zhen Xu, Qingchao Wang
Summary: In this study, glycyrrhizic acid (GA) was applied in the egg hatching and larviculture of dojo loach, showing that low dosage of GA could improve hatchability while high dosage inhibited larval body length growth.
Article
Virology
Zhenyu Huang, Mengting Zhan, Gaofeng Cheng, Ruiqi Lin, Xue Zhai, Haiou Zheng, Qingchao Wang, Yongyao Yu, Zhen Xu
Summary: The fish intestinal mucosa is an important site for the interaction between environmental microorganisms and the host, playing a crucial role in defense against pathogens and commensal colonization. This study found that viral infection in rainbow trout resulted in severe tissue damage, inflammation, and mucus increase in the gut. It also triggered a strong immune response and dysbiosis, highlighting the sensitivity of the microbiota-gut immune system relationship to viral infection. Consideration of opportunistic bacterial infection is important for controlling viral infection.
Article
Immunology
Mengya Wang, Zhenwei Chen, Yunhua Wang, Jiahong Zou, Shuaitong Li, Xiaolong Guo, Jian Gao, Qingchao Wang
Summary: This study demonstrated that the inclusion of CPC in largemouth bass diet may induce higher inflammatory potential during N. seriolae infection.
FRONTIERS IN IMMUNOLOGY
(2022)
Editorial Material
Physiology
Jianlong Ge, Yu-Hung Lin, Cristian Araneda, Qingchao Wang
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Jiahong Zou, Peng Hu, Mengya Wang, Zhenwei Chen, Huan Wang, Xiaolong Guo, Jian Gao, Qingchao Wang
Summary: High environmental ammonia leads to respiratory disorders and metabolic dysfunction in most fish species. This study focused on the largemouth bass hepatic response to ammonia loading. The results showed that ammonia exposure severely damaged the fish liver structure and altered the expression of genes involved in various metabolic pathways. Additionally, ammonia exposure also affected the oxidative phosphorylation and mitogen-activated protein kinase signaling pathways in the largemouth bass liver.
Review
Agriculture, Dairy & Animal Science
Qingchao Wang, Zhen Xu, Qinghui Ai
Summary: Arginine plays a crucial role in the nutrient metabolism, immune response, and antioxidant response of fish. Studies have shown that arginine influences energy balance and protein synthesis in fish by modulating specific signaling pathways.
Article
Immunology
Jia-feng Cao, Li-guo Ding, Qing-chao Wang, Guang-kun Han, Da-cheng Qin, Gao-feng Cheng, Zhao-ran Dong, Qing-jiang Mu, Wei-guang Kong, Xia Liu, Yong-yao Yu, Zhen Xu
Summary: This study demonstrated the important role of mTORC1 signaling in teleost B cells by using rapamycin treatment in a fish model. Inhibition of mTORC1 signaling by rapamycin decreased phagocytic capacity, proliferation, and Ig production of B cells, as well as affected specific IgM binding in serum and susceptibility to reinfection by Flavobacterium columnare.
JOURNAL OF IMMUNOLOGY
(2022)
Article
Fisheries
Hunter S. Bailey, Ashley N. Fincannon, Lee A. Fuiman
Summary: This study investigated the transfer of fatty acids from broodstock diets to eggs and the time needed for the eggs to equilibrate to the diet in Southern flounder. The findings indicate that different diet treatments significantly affect the fatty acid composition of eggs, and it takes 8-16 weeks for the eggs to adapt to changes in the adult diet. These results are important for improving broodstock diets and feeding protocols in stock-enhancement programs.
Article
Fisheries
Yu Liu, Mingtao Lei, Hector Victor, Yan Wang
Summary: This study confirms the feasibility of replacing raw fish diet with a formulated diet in commercial farming of large yellow croaker, which can increase fish survival and yield, and reduce feed cost and body lipid deposition.
Article
Fisheries
Xiaoyan Zhang, Lize San, Yucong Yang, Yuehong Tao, Jiangong Ren, Yufeng Liu, Zhongwei He, Jiashuo Di, Ziteng Pei, Guixing Wang, Jilun Hou
Summary: Gynogenesis is an effective technique for establishing homogeneous lines and confirming potential chromosomal mechanisms of sex determination in fish. This study successfully induced gynogenetic families in Thamnaconus modestus and established a complete method for gynogenesis induction.
Article
Fisheries
Julieta C. Martinelli, Megan Considine, Helen R. Casendino, Carolyn M. Tarpey, Isadora Jimenez-Hidalgo, Jacqueline L. Padilla-Gamino, Teri L. King, Lorenz Hauser, Steven Rumrill, Chelsea L. Wood
Summary: Shell-boring polychaetes have caused significant damage to mariculture operations worldwide, particularly in the US Pacific region. This study provides a comprehensive dataset on the prevalence, species distribution, and environmental associations of these parasites, highlighting the impact of season, culturing methods, and environmental factors on infestation.
Article
Fisheries
Juan Gao, Xueshan Li, Kangle Lu, Kai Song, Jian Zhang, Ling Wang, Chunxiao Zhang
Summary: This study investigated the effects of dietary protein levels on growth performance, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog tadpoles. The optimal dietary protein level for bullfrog tadpoles was estimated to be 42.49%-46.50% of the diet.
Article
Fisheries
Qiang Li, Lijun Duan, Dongsheng Jin, Yuxin Chen, Yirong Lou, Qianjin Zhou, Zhongjie Xu, Fangjie Chen, Hongxian Chen, Guizong Xu, Maocang Yan, Guanjun Yang, Jianfei Lu, Yanjun Zhang, Jiong Chen
Summary: This study developed a centrifugal microfluidic chip with on-chip RPA to detect five pathogenic microorganisms. The chip enabled the parallel analysis of six genetic markers from a single sample and allowed for the highly automated detection of multiple samples. Compared with PCR and DNA sequencing, the on-chip RPA assay showed high sensitivity and specificity for detecting multiple pathogens in shrimp aquaculture.
Article
Fisheries
Xingchen Huo, Pengxu Wang, Fengxia Zhao, Qian Liu, Qingqing Tian, Lingjie Tang, Maolin Lv, Zhaohui Wei, Chunrong Yang, Jianguo Su
Summary: Bacterial diseases in aquaculture ponds have negative effects on sustainable development. The use of composite I20 biotherapy has been shown to effectively treat bacterial diseases in bullfrog ponds, providing a new strategy for controlling bacterial diseases in aquaculture.
Article
Fisheries
Peng Yin, Takaya Saito, Per Gunnar Fjelldal, Bjorn Tharandur Bjornsson, Sofie Charlotte Remo, Sandeep Sharma, Rolf Erik Olsen, Kristin Hamre
Summary: This study aims to investigate the effect of seasonal changes in temperature and photoperiod on the redox metabolism of Atlantic salmon at the molecular level. The research findings suggest that the changing photoperiod and temperature influenced the redox metabolism of Atlantic salmon, highlighting the importance of oxidative status in the ecological implications.
Article
Fisheries
Nicholas Oppong Mensah, Jeffery Kofi Asare, Emmanuel Tetteh-Doku Mensah, Ernest Christlieb Amrago, Frank Osei Tutu, Anthony Donkor
Summary: This study investigates aquaculture farmers' preference for climate-smart aquaculture insurance products, the challenges they face, and their preferred insurance coverage. The results show that farmers prefer Climate-Induced Aquaculture Stock Mortality Insurance and the most significant constraint is the delay in claim settlement.
Article
Fisheries
Qiu-Ping Chai, Pei Wu, Wei-Dan Jiang, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Lin Feng, Xiao-Qiu Zhou
Summary: The study found that appropriate levels of potassium diformate (KDF) can enhance the immune defense and mediate the inflammatory process in fish, possibly through the regulation of T cell differentiation via JAK-STAT and NF-kappa B signaling pathways.
Article
Fisheries
Tian Zhu, Haomin Jia, Haopeng Zhang, Yujing Xiao, Cui Han, Jiaxin Yang
Summary: Chicken manure has significant effects on the cultivation of Chlorella and rotifers. The optimal amount of chicken manure extract for continuous cultivation is 10 mLL-1. Chicken manure can promote the growth of Chlorella and improve the fatty acid composition, indirectly enhancing the growth condition and fatty acid content of rotifers.
Article
Fisheries
Zheng Luo, Yang Yu, Zhenning Bao, Fuhua Li
Summary: This study analyzed the heritability and genetic correlation of two growth traits in Pacific white shrimp and evaluated the genomic prediction using different genomic selection models. The results showed that the NeuralNet model had the highest prediction accuracy and better prospects for predicting shrimp growth traits.
Article
Fisheries
Alberto Ruiz, Ignasi Sanahuja, Karl B. Andree, Dolors Furones, Paul G. Holhorea, Josep A. Calduch-Giner, Jose J. Pastor, Marc Vinas, Jaume Perez-Sanchez, Sofia Morais, Enric Gisbert
Summary: Supplementing diets with a combination of spice oleoresins can reduce lipid accumulation and inflammation in farmed fish. The combination of spice oleoresins also has an immunomodulatory effect on the fish's intestinal immune system, potentially offering anti-inflammatory benefits.
Article
Fisheries
Beibei Zhao, Renhui Mei, Le Li, Di Hu, Lei Li
Summary: This study reveals that JfCXCL8_L1a and JfCXCL8_L1b have different immune pathways, and JfCXCL8_L1b plays a significant role in enhancing the adaptive immunity of T cell-dependent antigen.
Article
Fisheries
Yuhang Liu, Danying Cao, Nan Wu, Xuyang Zhao, Qingsong Zhu, Lian Su, Fatima Altaf, Qianqian Zhang, Haokun Liu, Yongming Li, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Aihua Li, Yaping Wang, Xiao-Qin Xia
Summary: Based on previous research, sinomenine has been found to protect mucosal immunity in farmed fish species by preventing intestinal pathological changes and regulating gene expression related to inflammation. It also enhances immune homeostasis and controls the growth of pathogenic bacteria.
