Article
Fisheries
Min Liu, Chen Chen, Qi-Cheng Wu, Jia-Le Chen, Li-Shang Dai, Sheng Hui Chu, Qiu-Ning Liu
Summary: The study identified PcChitinase 2 gene sequence from P. clarkii and investigated its spatial and temporal expression profiles. The gene was found to be expressed unequally in different tissues, with the highest expression in stomach, gut, and hepatopancreas. Knockdown of PcChitinase 2 gene led to suppression of most Toll-pathway-related immune genes, indicating its involvement in the innate immune responses of P. clarkii through modulation of the toll pathway.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Qing-Ri Jin, Jing-Wei Mao, Fei Zhu
Summary: Anoectochilus roxburghii polysaccharides (ARPs) have significant effects on the immune system of crayfish, increasing the survival rate of crayfish infected with white spot syndrome virus (WSSV). ARPs can also regulate the expression levels of multiple immune genes, promote immune enzyme activity, and induce apoptosis in crayfish hemocytes.
Article
Fisheries
Yinan Jiang, Yuting Wang, Yingying Zhang, Hui Yang
Summary: A novel scavenger receptor B (PcSRB) was identified in the Chinese mitten crab, which plays an important role in immune defense, particularly in the recognition and binding of pathogens.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Bingbing Yang, Qianqian Li, Mingda Zhang, Sihan Lin, Xiuli Shen, Zhiqiang Du
Summary: In this study, a peroxiredoxin 4 gene was cloned from crayfish and named Pc-prx 4, which may be related to crayfish innate immune defense responses. Further studies are needed to illuminate the molecular mechanism of Pc-prx 4 in the crayfish immune system.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Rumiana Bakalova, Ichio Aoki, Zhivko Zhelev, Tatsuya Higashi
Summary: Recent studies have shown that impaired respiration can lead to redox imbalance in NAD(+)/NADH and NADP(+)/NADPH pairs, triggering two metabolic pathways that affect mitochondrial function, senescence, and cell proliferation. The beta-oxidation shuttle disrupts the balance of NAD+/NADH in mitochondria, while the hydride transfer complex (HTC) cycle maintains the balance of NAD(+)/NADH in the cytoplasm and disrupts the balance of NADP(+)/NADPH. Senescence is influenced by high cytoplasmic NADH but low NADPH, while proliferation depends on high levels of cytoplasmic NAD(+) and NADPH, which are regulated by mitochondria. Therefore, controlling the HTC cycle is crucial for determining cell fate - senescence or proliferation.
Article
Fisheries
Yunfei Zhang, Chongyang Xiao, Fei Zhu
Summary: The study showed that dietary supplementation of 40 mg/kg quercetin significantly reduced crayfish mortality and WSSV copy number after challenge, while also increasing the immune activity such as catalase and lysozyme. Additionally, dietary quercetin enhanced the expression of immune-related genes and induced apoptosis in hemocytes of crayfish.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Lei Zhu, Xiaoyu Wang, Libo Hou, Xinyu Jiang, Chen Li, Jie Zhang, Chao Pei, Xianliang Zhao, Li Li, Xianghui Kong
Summary: This study investigated the immune response of P. clarkii to A. veronii infection, revealing significant tissue damage and impaired immune system in infected crayfish. Moreover, the activities of immune-related enzymes and the expression levels of immune-related genes were found to be altered in response to A. veronii infection, indicating a comprehensive innate immune response in P. clarkii.
AQUACULTURE REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Liang Luo, Yue Xu, Shihui Wang, Rui Zhang, Kun Guo, Wei Xu, Zhigang Zhao
Summary: In order to improve the management and protection of crayfish genetic diversity and germplasm resources, the whole mitochondrial genome sequence of C. dauricus was compared with that of P. clarkii using Illumina sequencing technology. The length of C. dauricus mitochondrial genome is 15580 bp, with a base composition of A (31.84%), G (17.66%), C (9.42%), and T (41.08%), and a C + G content of 27.08%. Most of the protein-coding genes have a Ka/Ks ratio lower than 1, indicating weak natural selection, except for nad 2, nad 5, and cox 1. The Ka/Ks ratio of cox 3 is the lowest (less than 0.1), indicating strong natural selection pressure and functional constraint.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Fisheries
Ying Huang, Ying Jiang, Miao-Miao Wang, Min-Yi Chen, Huan-Gen Chen, Heng-Yuan Chen, Wen-Jie Liu, Xiao-Rui Li, Xiao-Lei Han
Summary: This study cloned and characterized a mannose-binding lectin (MBL) called PcMBL from the crayfish Procambarus clarkii. PcMBL plays important roles in nonself recognition and clearance of invading microorganisms. It was found that PcMBL can influence the transcription of antimicrobial peptide genes and has the ability to bind to various microorganisms and carbohydrates. Furthermore, recombinant PcMBL can facilitate bacterial clearance, inhibit biofilm formation and growth, and reduce mortality in infected crayfish.
AQUACULTURE REPORTS
(2023)
Article
Biochemistry & Molecular Biology
Lara Rouco, Rebeca Alvarino, Amparo Alfonso, Maria J. Romero, Rosa Pedrido, Marcelino Maneiro
Summary: This study investigates the antioxidant properties of four manganese(II) complexes with fluorescent dyes and their protective effects on SH-SY5Y neuroblastoma cells. The complexes showed significant antioxidant activity and improved cell survival by reducing reactive oxygen species release. The incorporation of the fluorescent label allowed the study of their cellular uptake in the neuroblastoma cells.
JOURNAL OF INORGANIC BIOCHEMISTRY
(2022)
Review
Chemistry, Medicinal
Stephen T. Sonis
Summary: Toxicities associated with radiation therapy can be effectively mitigated through interventions aimed at disrupting the biological cascade of toxicity development, with oxidative stress being a key initiator of normal tissue injury. Attempts to supplement endogenous superoxide dismutases or develop synthetic dismutase mimetics have shown some potential, with avasopasem manganese emerging as a promising dismutase mimetic in clinical trials for reducing severe oral mucositis in head and neck cancer patients undergoing chemoradiation.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2021)
Article
Fisheries
Jia Liu, Cheng Chen, Hui Du, Dexin Wang, Haixiang Ma, Gaoxue Wang, Tao Liu, Erlong Wang
Summary: This study evaluated the antiviral effects of twelve herbal extracts in a WSSV-infected crayfish model and found that Sophora flavescens extract showed the highest inhibition rate. Further investigation on the main bioactive component, matrine, showed that it significantly inhibited WSSV replication and improved the survival rate of infected crayfish. The study also revealed the mechanisms of matrine's antiviral effects.
Article
Biochemistry & Molecular Biology
Matic Broz, Veronika Furlan, Samo Lesnik, Marko Jukic, Urban Bren
Summary: A mutation in the MnSOD gene (rs4880, Ala16Val) has been linked to various types of cancer and autoimmune diseases. This study shows that this mutation disrupts the secondary structure of MnSOD and reduces its activity.
Article
Multidisciplinary Sciences
Li-Qiang Wang, Yeyang Ma, Han-Ye Yuan, Kun Zhao, Mu-Ya Zhang, Qiang Wang, Xi Huang, Wen-Chang Xu, Bin Dai, Jie Chen, Dan Li, Delin Zhang, Zhengzhi Wang, Liangyu Zou, Ping Yin, Cong Liu, Yi Liang
Summary: The authors determined the cryo-EM structure of SOD1 fibrils, providing insights into the conversion of SOD1 during the pathogenesis of ALS.
NATURE COMMUNICATIONS
(2022)
Article
Fisheries
Lei Zhu, Gaoliang Yuan, Xinyu Jiang, Jie Zhang, Xianliang Zhao, Chao Pei, Li Li, Xianghui Kong
Summary: The Rab5 and Rab6 genes from crayfish Procambarus clarkii were cloned, and their involvement in bacterial and viral infections in the immune response of P. clarkii was revealed. The genes showed wide tissue distribution and increased expression levels after infection with pathogens. Silencing of PcRab5 and PcRab6 affected the mortality rate of crayfish challenged by pathogens, indicating their significant roles in the immune response.
Article
Fisheries
Hunter S. Bailey, Ashley N. Fincannon, Lee A. Fuiman
Summary: This study investigated the transfer of fatty acids from broodstock diets to eggs and the time needed for the eggs to equilibrate to the diet in Southern flounder. The findings indicate that different diet treatments significantly affect the fatty acid composition of eggs, and it takes 8-16 weeks for the eggs to adapt to changes in the adult diet. These results are important for improving broodstock diets and feeding protocols in stock-enhancement programs.
Article
Fisheries
Yu Liu, Mingtao Lei, Hector Victor, Yan Wang
Summary: This study confirms the feasibility of replacing raw fish diet with a formulated diet in commercial farming of large yellow croaker, which can increase fish survival and yield, and reduce feed cost and body lipid deposition.
Article
Fisheries
Xiaoyan Zhang, Lize San, Yucong Yang, Yuehong Tao, Jiangong Ren, Yufeng Liu, Zhongwei He, Jiashuo Di, Ziteng Pei, Guixing Wang, Jilun Hou
Summary: Gynogenesis is an effective technique for establishing homogeneous lines and confirming potential chromosomal mechanisms of sex determination in fish. This study successfully induced gynogenetic families in Thamnaconus modestus and established a complete method for gynogenesis induction.
Article
Fisheries
Julieta C. Martinelli, Megan Considine, Helen R. Casendino, Carolyn M. Tarpey, Isadora Jimenez-Hidalgo, Jacqueline L. Padilla-Gamino, Teri L. King, Lorenz Hauser, Steven Rumrill, Chelsea L. Wood
Summary: Shell-boring polychaetes have caused significant damage to mariculture operations worldwide, particularly in the US Pacific region. This study provides a comprehensive dataset on the prevalence, species distribution, and environmental associations of these parasites, highlighting the impact of season, culturing methods, and environmental factors on infestation.
Article
Fisheries
Juan Gao, Xueshan Li, Kangle Lu, Kai Song, Jian Zhang, Ling Wang, Chunxiao Zhang
Summary: This study investigated the effects of dietary protein levels on growth performance, antioxidant capacity, digestive enzyme activity, and metamorphosis rate of bullfrog tadpoles. The optimal dietary protein level for bullfrog tadpoles was estimated to be 42.49%-46.50% of the diet.
Article
Fisheries
Qiang Li, Lijun Duan, Dongsheng Jin, Yuxin Chen, Yirong Lou, Qianjin Zhou, Zhongjie Xu, Fangjie Chen, Hongxian Chen, Guizong Xu, Maocang Yan, Guanjun Yang, Jianfei Lu, Yanjun Zhang, Jiong Chen
Summary: This study developed a centrifugal microfluidic chip with on-chip RPA to detect five pathogenic microorganisms. The chip enabled the parallel analysis of six genetic markers from a single sample and allowed for the highly automated detection of multiple samples. Compared with PCR and DNA sequencing, the on-chip RPA assay showed high sensitivity and specificity for detecting multiple pathogens in shrimp aquaculture.
Article
Fisheries
Xingchen Huo, Pengxu Wang, Fengxia Zhao, Qian Liu, Qingqing Tian, Lingjie Tang, Maolin Lv, Zhaohui Wei, Chunrong Yang, Jianguo Su
Summary: Bacterial diseases in aquaculture ponds have negative effects on sustainable development. The use of composite I20 biotherapy has been shown to effectively treat bacterial diseases in bullfrog ponds, providing a new strategy for controlling bacterial diseases in aquaculture.
Article
Fisheries
Peng Yin, Takaya Saito, Per Gunnar Fjelldal, Bjorn Tharandur Bjornsson, Sofie Charlotte Remo, Sandeep Sharma, Rolf Erik Olsen, Kristin Hamre
Summary: This study aims to investigate the effect of seasonal changes in temperature and photoperiod on the redox metabolism of Atlantic salmon at the molecular level. The research findings suggest that the changing photoperiod and temperature influenced the redox metabolism of Atlantic salmon, highlighting the importance of oxidative status in the ecological implications.
Article
Fisheries
Nicholas Oppong Mensah, Jeffery Kofi Asare, Emmanuel Tetteh-Doku Mensah, Ernest Christlieb Amrago, Frank Osei Tutu, Anthony Donkor
Summary: This study investigates aquaculture farmers' preference for climate-smart aquaculture insurance products, the challenges they face, and their preferred insurance coverage. The results show that farmers prefer Climate-Induced Aquaculture Stock Mortality Insurance and the most significant constraint is the delay in claim settlement.
Article
Fisheries
Qiu-Ping Chai, Pei Wu, Wei-Dan Jiang, Yang Liu, Hong-Mei Ren, Xiao-Wan Jin, Lin Feng, Xiao-Qiu Zhou
Summary: The study found that appropriate levels of potassium diformate (KDF) can enhance the immune defense and mediate the inflammatory process in fish, possibly through the regulation of T cell differentiation via JAK-STAT and NF-kappa B signaling pathways.
Article
Fisheries
Tian Zhu, Haomin Jia, Haopeng Zhang, Yujing Xiao, Cui Han, Jiaxin Yang
Summary: Chicken manure has significant effects on the cultivation of Chlorella and rotifers. The optimal amount of chicken manure extract for continuous cultivation is 10 mLL-1. Chicken manure can promote the growth of Chlorella and improve the fatty acid composition, indirectly enhancing the growth condition and fatty acid content of rotifers.
Article
Fisheries
Zheng Luo, Yang Yu, Zhenning Bao, Fuhua Li
Summary: This study analyzed the heritability and genetic correlation of two growth traits in Pacific white shrimp and evaluated the genomic prediction using different genomic selection models. The results showed that the NeuralNet model had the highest prediction accuracy and better prospects for predicting shrimp growth traits.
Article
Fisheries
Alberto Ruiz, Ignasi Sanahuja, Karl B. Andree, Dolors Furones, Paul G. Holhorea, Josep A. Calduch-Giner, Jose J. Pastor, Marc Vinas, Jaume Perez-Sanchez, Sofia Morais, Enric Gisbert
Summary: Supplementing diets with a combination of spice oleoresins can reduce lipid accumulation and inflammation in farmed fish. The combination of spice oleoresins also has an immunomodulatory effect on the fish's intestinal immune system, potentially offering anti-inflammatory benefits.
Article
Fisheries
Beibei Zhao, Renhui Mei, Le Li, Di Hu, Lei Li
Summary: This study reveals that JfCXCL8_L1a and JfCXCL8_L1b have different immune pathways, and JfCXCL8_L1b plays a significant role in enhancing the adaptive immunity of T cell-dependent antigen.
Article
Fisheries
Yuhang Liu, Danying Cao, Nan Wu, Xuyang Zhao, Qingsong Zhu, Lian Su, Fatima Altaf, Qianqian Zhang, Haokun Liu, Yongming Li, Bruno Hamish Unger, Yingyin Cheng, Wanting Zhang, Aihua Li, Yaping Wang, Xiao-Qin Xia
Summary: Based on previous research, sinomenine has been found to protect mucosal immunity in farmed fish species by preventing intestinal pathological changes and regulating gene expression related to inflammation. It also enhances immune homeostasis and controls the growth of pathogenic bacteria.