Article
Materials Science, Multidisciplinary
C. J. Rietema, M. A. Walker, T. R. Jacobs, A. J. Clarke, K. D. Clarke
Summary: This study demonstrates the reliable measurement of relative differences in vanadium carbonitride precipitate volume fraction in ferritic/martensitic steels using ToF-SIMS; additionally, associating matrix elements (iron and chromium) to nitrogen-containing ion clusters significantly reduces the 'matrix effect' biasing nitrogen detection towards nitride precipitates, providing a potential high-throughput method for measuring interstitial nitrogen content in steels with ToF-SIMS.
MATERIALS CHARACTERIZATION
(2021)
Article
Chemistry, Physical
Margarita Hierro-Oliva, Amparo M. Gallardo-Moreno, Maria Luisa Gonzalez-Martin
Summary: Research shows that UV-C light treatment on Ti6Al4V surfaces can alter the conformation, orientation, and packing of protein layers, with low irradiation time leading to protein denaturation and 15 hours of irradiation stabilizing the surface changes favoring protein adsorption.
Article
Engineering, Chemical
Sian M. La Vars, Jamie S. Quinton, Sarah L. Harmer
Summary: The study revealed that the presence of yeast extract can interfere with the action of EPS on the surface of pyrite exposed to the thermophilic archaeon A. brierleyi, potentially impeding chemical and biological reactions and interactions. Furthermore, it was found that A. brierleyi produces very little EPS and is unlikely to alter the mineral surface through a contact mechanism.
MINERALS ENGINEERING
(2021)
Article
Biotechnology & Applied Microbiology
Hangjun Huang, Haiqiang Liu, Weiwei Ma, Liang Qin, Lulu Chen, Hua Guo, Hualei Xu, Jinrong Li, Chenyu Yang, Hao Hu, Ran Wu, Difan Chen, Jinchao Feng, Yijun Zhou, Junli Wang, Xiaodong Wang
Summary: A novel metabolomics analysis technique called MALDI-MSI-PTMA was developed to detect and image metabolites from plant tissues. This technique overcomes the limitation of intact plant tissues by homogenizing plant tissues, preparing PTMA moulds, and spraying matrix on PTMA sections. The technique has advantages such as no need of sample separation and enrichment, high-throughput metabolite detection and imaging, high-stability mass spectrometry data acquisition and imaging reconstruction, and high reproducibility of data.
PLANT BIOTECHNOLOGY JOURNAL
(2023)
Review
Chemistry, Analytical
Lina Shi, Sutong Liu, Xue Li, Xiwei Huang, Hongzhi Luo, Qianwen Bai, Zhu Li, Lijun Wang, Xiaoxin Du, Cheng Jiang, Shan Liu, Chenzhong Li
Summary: High-throughput screening platforms are crucial for processing large amounts of experimental data rapidly and efficiently. The development of miniaturized high-throughput screening platforms is essential in the fields of biotechnology, medicine, and pharmacology. Droplet microarrays, as novel screening platforms, can effectively overcome the disadvantages of traditional microtiter plates, such as high reagent and cell consumption, low throughput, and cross-contamination. This article provides a brief overview of the preparation and compound addition methods of droplet microarrays, as well as their applications in biomedicine, drug development, and individualized medicine.
Article
Materials Science, Multidisciplinary
J. G. Acheson, L. Robinson, S. McKillop, S. Wilson, M. J. McIvor, B. J. Meenan, A. R. Boyd
Summary: This study utilized radio frequency magnetron sputtering to deposit amorphous Sr-containing calcium phosphate coatings and characterized them using surface analytical techniques. The results showed that the amorphous Sr-containing coating had a homogeneous distribution of Sr on the surface.
MATERIALS CHARACTERIZATION
(2021)
Article
Engineering, Biomedical
Cristiane M. Franca, Avathamsa Athirasala, Ramesh Subbiah, Anthony Tahayeri, Prakash Selvakumar, Amin Mansoorifar, Sivaporn Horsophonphong, Ashley Sercia, Lina Nih, Luiz E. Bertassoni
Summary: This study introduces a strategy to bioprint endothelial and stem-cell laden microgels in a geometrically controlled manner, allowing these cells to form mature and functional pericyte-supported vascular capillaries. These pre-vascularized constructs can then be injected into the body in a minimally invasive manner. The results demonstrate that this approach offers scalable and customizable solutions for tissue regeneration, addressing a significant issue in the field of regenerative medicine.
ADVANCED HEALTHCARE MATERIALS
(2023)
Article
Engineering, Environmental
Yiren Li, Jian Liu, Yiheng Wang, Xianjin Tang, Jianming Xu, Xingmei Liu
Summary: Cadmium (Cd) and lead (Pb) are common elements in contaminated sites and their behavior in the soil can be influenced by competition for adsorption sites. This study used adsorption experiments, multi-surface models, and advanced spectroscopy technology to explain the adsorption mechanisms of Cd and Pb and determine the contribution of each component in the competitive system. The results showed that pH is a key factor influencing the adsorption contribution of soil components, with soil organic matter being the dominant adsorbent for both Cd and Pb. Clay minerals play a role at low pH, while Fe/Al oxides primarily adsorb metals at high pH. Additionally, the competitive effect of Pb on Cd was mainly observed on soil organic matter rather than clay minerals, emphasizing the importance of considering this competition in soils with high organic matter content.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Vanessa Hui Yin Chou, Wing Chung Liu, Mallory Wittwer, Hortense Le Ferrand, Matteo Seita
Summary: Reinforced composites with controlled microstructure can achieve exceptional properties, but characterizing their microstructural features is challenging. This study presents a simple, inexpensive, and high-throughput method using directional reflectance microscopy (DRM) to assess the surface microstructure of microplatelet reinforced composites. The results demonstrate the potential of DRM as a high-throughput method for evaluating microstructural information in reinforced composites.
Review
Chemistry, Analytical
Gabrielle Kosoy, Benjamin L. Miller
Summary: Arrayed imaging reflectometry (AIR) is a thin-film interference sensor technique that can be used for detecting various biomolecules and pathogens, and it has high sensitivity and multiplex capability.
Article
Materials Science, Multidisciplinary
Zhu Wang, Zi-Xuan Liu, Jie Jin, De-Zhi Tang, Lei Zhang
Summary: The selective corrosion mechanism of CoCrFeMoNi HEA in the transpassive region was studied using electrochemical tests and ToF-SIMS. It was found that Mo and Cr oxides are more enriched in the local passive films formed on the mu and sigma phases than those formed on the FCC phase. As the applied potential increases, the passive film thickens, while the Mo and Cr content decreases, leading to passive film degradation. The local passive films formed on the FCC surface are more susceptible to dissolution in the transpassive region due to the lower content of Cr and Mo in the FCC films. Therefore, selective corrosion of FCC phase occurs in the transpassive region.
Article
Chemistry, Physical
Zuocheng Wang, Charly Carriere, Antoine Seyeux, Sandrine Zanna, Dimitri Mercier, Philippe Marcus
Summary: The thermal stability of surface oxides on Ni-20Cr and Ni-20Cr-10Mo alloys was investigated, with electrochemical passivation significantly improving the thermal stability of the oxide and even more so in the Mo-containing alloy. These findings are valuable for developing corrosion protection strategies.
APPLIED SURFACE SCIENCE
(2022)
Article
Materials Science, Multidisciplinary
Zhu Wang, Jie Jin, Guo-Hui Zhang, Xue-Hua Fan, Lei Zhang
Summary: The study found that the content of Fe and Mo species in the passive film of high-entropy alloy decreases with increasing temperature, leading to the degradation of the passive film. High-entropy alloy exhibits different corrosion behaviors at different temperatures, with selective dissolution of crystal phases occurring below 50 degrees Celsius and pitting corrosion occurring above 60 degrees Celsius.
Article
Engineering, Biomedical
Henry H. Hwang, Shangting You, Xuanyi Ma, Leilani Kwe, Grace Victorine, Natalie Lawrence, Xueyi Wan, Haixu Shen, Wei Zhu, Shaochen Chen
Summary: The study introduces an integrated 3D bioprinting platform based on microscale continuous optical printing technology, capable of high throughput fabrication of complex 3D biomedical samples in multiwell plate formats. The platform was used to showcase constructs with varying spatial geometries, tunable mechanical properties, and reproducibility, as well as in situ fabrication of live hepatocellular carcinoma 3D tissue scaffolds and dual-tissue fabrication with different cell types. This advancement enables rapid generation of in vitro 3D tissue models for high throughput preclinical drug screening and disease modeling.
Article
Biochemical Research Methods
Ruben C. Boot, Alessio Roscani, Lennard van Buren, Samadarshi Maity, Gijsje H. Koenderink, Pouyan E. Boukany
Summary: We developed a microfluidic chip for high-throughput measurement of the viscoelastic deformation behavior of cell spheroids. The chip allows for parallel loading of spheroids and aspiration into adjacent channels, providing accurate deformation data. This chip enables the mechanophenotyping of different tissue types and investigation of the link between cell-intrinsic properties and overall tissue behavior.
Article
Chemistry, Analytical
Wil Gardner, Andrew L. Hook, Morgan R. Alexander, Davide Ballabio, Suzanne M. Cutts, Benjamin W. Muir, Paul J. Pigram
ANALYTICAL CHEMISTRY
(2020)
Article
Multidisciplinary Sciences
Cindy Vallieres, Andrew L. Hook, Yinfeng He, Valentina Cuzzucoli Crucitti, Grazziela Figueredo, Catheryn R. Davies, Laurence Burroughs, David A. Winkler, Ricky D. Wildman, Derek J. Irvine, Morgan R. Alexander, Simon Avery
Article
Chemistry, Multidisciplinary
Andrew L. Hook, John Hogwood, Elaine Gray, Barbara Mulloy, Catherine L. R. Merry
Summary: This study presents a method using ToF-SIMS and multivariate analysis to analyze over 400 different GAGs in a short time frame, successfully distinguishing between 6 GAG types, including heparin samples from different animal sources.
COMMUNICATIONS CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Yinfeng He, Meisam Abdi, Gustavo F. Trindade, Belen Begines, Jean-Frederic Dubern, Elisabetta Prina, Andrew L. Hook, Gabriel Y. H. Choong, Javier Ledesma, Christopher J. Tuck, Felicity R. A. J. Rose, Richard J. M. Hague, Clive J. Roberts, Davide S. A. De Focatiis, Ian A. Ashcroft, Paul Williams, Derek J. Irvine, Morgan R. Alexander, Ricky D. Wildman
Summary: The study demonstrates that multi-material inkjet-based 3D printing can achieve personalized medical devices with controlled deformation and reduced biofilm formation in composite structures.
Article
Engineering, Biomedical
Yinfeng He, Jeni Luckett, Belen Begines, Jean-Frederic Dubern, Andrew L. Hook, Elisabetta Prina, Felicity R. A. J. Rose, Christopher J. Tuck, Richard J. M. Hague, Derek J. Irvine, Paul Williams, Morgan R. Alexander, Ricky D. Wildman
Summary: This study shows that customized medical devices can be produced through ink-jet based 3D printing with bacterial biofilm inhibiting formulations. These devices exhibit inhibitory properties against bacterial biofilm growth and non-toxicity to mammalian cells both in vitro and in vivo.
Article
Multidisciplinary Sciences
Xuan Xue, Christopher M. Coleman, Joshua D. Duncan, Andrew L. Hook, Jonathan K. Ball, Cameron Alexander, Morgan R. Alexander
Summary: This study evaluated the effectiveness of various personal protective equipment (PPE) materials in terms of viral adsorption and antiviral potency against SARS-CoV-2. The results showed that current polymer-based PPE had limited ability to reduce the viral titre of SARS-CoV-2. The surface chemistry of the materials was found to play a role in determining the extent of virion adsorption.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Jean-Frederic Dubern, Andrew L. Hook, Alessandro M. Carabelli, Chien-Yi Chang, Christopher A. Lewis-Lloyd, Jeni C. Luckett, Laurence Burroughs, Adam A. Dundas, David J. Humes, Derek J. Irvine, Morgan R. Alexander, Paul Williams
Summary: Innovative approaches are urgently needed to prevent catheter-associated urinary tract infections (CAUTIs). A newly discovered acrylate copolymer has shown promising resistance against bacterial biofilm formation, swarming, encrustation, and host protein deposition, all of which are major challenges in preventing CAUTIs. The copolymer, poly(tert-butyl cyclohexyl acrylate), combined with poly(2-hydroxy-3-phenoxypropyl acrylate) has demonstrated its potential as a urinary catheter coating by retaining its bioinstructive properties and maintaining resistance against various uropathogens.
Article
Biophysics
Heba Khateb, Andrew L. Hook, Stefanie Kern, Julie A. Watts, Sonali Singh, Darryl Jackson, Luisa Marinez-Pomares, Paul Williams, Morgan R. Alexander
Summary: The use of OrbiTrap analyzer with SIMS (3D OrbiSIMS) enables label-free mass spectrometry of Psl, accurately identifying secondary ion peaks specific to the Psl structure. By studying P. aeruginosa biofilm and purified Psl, 17 peaks associated with Psl fragments within the biofilm matrix were confidently identified. Additionally, the neutral loss sequences approach can also identify multiple oligosaccharide fragments without a biological reference sample.
Article
Chemistry, Multidisciplinary
See Yoong Wong, Andrew L. Hook, Wil Gardner, Chien-Yi Chang, Ying Mei, Martyn C. Davies, Paul Williams, Morgan R. Alexander, Davide Ballabio, Benjamin W. Muir, David A. Winkler, Paul J. Pigram
Summary: Biofilm formation is a major problem in hospitals, and researching biofilm-resistant materials is critical. Polymer microarrays can efficiently discover new biofilm-resistant polymers. This study investigates bacterial attachment and surface chemistry on a polymer microarray to better understand Pseudomonas aeruginosa biofilm formation. Analyzing the data using linear multivariate analysis and a nonlinear self-organizing map reveals fragment ions associated with bacterial biofilm formation. Considering these insights, a second analysis is conducted that explicitly considers interactions between key fragments. This improved model provides chemical insights for designing materials that prevent pathogen attachment.
ADVANCED MATERIALS INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Alessandro M. Carabelli, Marco Isgro, Olutoba Sanni, Grazziela P. Figueredo, David A. Winkler, Laurence Burroughs, Andrew J. Blok, Jean-Frederic Dubern, Francesco Pappalardo, Andrew L. Hook, Paul Williams, Morgan R. Alexander
ACS APPLIED BIO MATERIALS
(2020)
Article
Engineering, Biomedical
Taranjit Singh, Andrew L. Hook, Jeni Luckett, Manfred F. Maitz, Claudia Sperling, Carsten Werner, Martyn C. Davies, Derek J. Irvine, Paul Williams, Morgan R. Alexander
Article
Materials Science, Biomaterials
Laurence Burroughs, Waheed Ashraf, Sonali Singh, Luisa Martinez-Pomares, Roger Bayston, Andrew L. Hook
BIOMATERIALS SCIENCE
(2020)
Article
Materials Science, Multidisciplinary
Hassan M. Rostam, Leanne E. Fisher, Andrew L. Hook, Laurence Burroughs, Jeni C. Luckett, Grazziela P. Figueredo, Chidimma Mbadugha, Alvin C. K. Teo, Arsalan Latif, Lisa Kammerling, Mitchell Day, Karen Lawler, David Barrett, Somaia Elsheikh, Mohammad Ilyas, David A. Winkler, Morgan R. Alexander, Amir M. Ghaemmaghami
Article
Materials Science, Biomaterials
Yasin Kurmoo, Andrew L. Hook, Daniel Harvey, Jean-Frederic Dubern, Paul Williams, Stephen P. Morgan, Sergiy Korposh, Morgan R. Alexander
BIOMATERIALS SCIENCE
(2020)
Article
Chemistry, Multidisciplinary
Adam A. Dundas, Andrew L. Hook, Morgan R. Alexander, Samuel W. Kingman, Georgios Dimitrakis, Derek J. Irvine
REACTION CHEMISTRY & ENGINEERING
(2019)
Article
Chemistry, Physical
Qi-Wen Chen, Ze-Qing Guo, Jian-Ping Zhou
Summary: Multifunctional continuous solid solutions NFMTO-x were successfully synthesized via a one-step hydrothermal method by controlling the ratio of Mg and Fe. The NFMTO-x materials exhibited enhanced visible light response, effective adsorption and photocatalytic degradation of organic pollutants, CO2 methanation capability, and easy recyclability due to their magnetic properties. This research provides a significant multifunctional material for water purification.
APPLIED SURFACE SCIENCE
(2024)
Review
Chemistry, Physical
George E. Stan, Maziar Montazerian, Adam Shearer, Bryan W. Stuart, Francesco Baino, John C. Mauro, Jose M. F. Ferreira
Summary: Bioactive glasses have the ability to form strong bonds with tissues and release therapeutic ions. However, their biomechanical compatibility limits their use in load-bearing applications. The use of magnetron sputtering technology to fabricate BG coatings shows promise in improving their efficacy and potential for application.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zhaoxuan Wang, Zhicheng Yan, Zhigang Qi, Yu Feng, Qi Chen, Ziqi Song, Meng Huang, Peng Jia, Ki Buem Kim, Weimin Wang
Summary: The corrosion behavior of Fe-60 and Fe-83 ribbons in 0.6 M NaCl was studied. Fe-60 exhibited a local corrosion mode and formed a stable passivation film with higher corrosion resistance, while Fe-83 showed a combination of local and global corrosion modes and had lower corrosion resistance. Controlling the precipitation of nanocrystalline phases and increasing the POx content in the passivation film significantly improved the corrosion resistance of Fe-based glassy alloys.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hao-Kai Peng, Sheng-Yen Zheng, Wei-Ning Kao, Ting-Chieh Lai, Kai-Sheun Lee, Yung- Hsien Wu
Summary: This study investigates the effects of high energy/fluence proton radiation on the performance of HfZrOx-based FeFETs memory with different Zr content. The results show that the characteristics of FeFETs are influenced by proton radiation, and the extent of the influence depends on the Zr content. FeFETs with 50% Zr content exhibit minimal changes in memory window and demonstrate good endurance and retention performance.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Zongyi Yue, Guangyi Wang, Zengguang Huang, Sihua Zhong
Summary: In this study, AZO and ITO films were successfully tuned as excellent passivation layers for c-Si surfaces, achieving effective minority carrier lifetime and outstanding optical properties through the optimization of annealing temperature and interfacial silicon oxide.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Martin Hruska, Jan Kejzlar, Jaroslav Otta, Premysl Fitl, Michal Novotny, Jakub Cizek, Oksana Melikhova, Matej Micusik, Peter Machata, Martin Vrnata
Summary: This paper presents a detailed study on the hydrogen sensing capabilities of highly nanoporous black gold films. The films exhibit fast response and recovery times at low temperatures. Different levels of nanoporosity were prepared and tested to investigate the sensing properties, and it was found that nanoporous black gold is suitable for hydrogen sensing. The sensitivity of the film depends on its nanoporosity.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yupu Wang, Gaofeng Teng, Chun To Yiu, Junyi Zhu
Summary: In the study of BM-SCO and HSCO thin films, it was found that H vacancies tend to prefer sites near the external surface or oxygen vacancy channels (OVCs), while H interstitials prefer sites of oxygen on a layer that contains six-fold coordinated Co. These findings not only enrich the understanding of complex surface phenomena of defect formation but also provide an explanation for the reversibility during phase transformation.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jiafeng Lu, Linping Teng, Qinxiao Zhai, Chunhua Wang, Matthieu Lancry, Ye Dai, Xianglong Zeng
Summary: In this study, we achieved full control of fiber nanograting orientation by manipulating laser polarization, and tailored space variant fiber nanogratings, which expanded the diversity in fiber nanograting engineering.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yibo Liu, Yujie Tao, Yue Liu, Qi Sun, Qinrong Lin, Kexin Kang, Qinghua Zhang, Qingjie Sun
Summary: This study investigates the wettability of the Ti-Cu-Fe multi-metal system, specifically the wetting behaviors of CuSi3 droplets on TC4 and 304SS plates. The results show that the CO2 + Ar gas atmosphere significantly affects interfacial mass transfer, thus influencing the wettability of the systems.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Jimei Liu, Fei Wang, Rong Guo, Yuqi Liu, Mengyu Zhang, Jaka Sunarso, Dong Liu
Summary: This study developed Co/MXene composites with anti-corrosion properties by varying the cobalt content. These composites exhibited remarkable electromagnetic absorption performance and high resistance to corrosion under various corrosive conditions. The study also revealed the mechanism of electron transfer from cobalt to MXene and the electromagnetic dissipation behavior originated from polarization loss alone.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Moujie Huang, Yongsong Ma, Jingbo Yang, Lingyun Xu, Hangqi Yang, Miao Wang, Xin Ma, Xin Xia, Junhao Yang, Deli Wang, Chuang Peng
Summary: Strong metal-support interactions (SMSIs) are important for enhancing catalytic activities and stability in thermal catalysis. This study demonstrates a method to create SMSIs in electrocatalysis using carbon nanotubes and Ru nanoparticles, resulting in excellent catalytic activity and stability.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Ravi Trivedi, Brinti Mondal, Nandini Garg, Brahmananda Chakraborty
Summary: This study explores the potential of biphenylene as a nanocarrier for the delivery of the anticancer drug cisplatin. It is found that biphenylene offers physical stability, rapid release rate, solubility, and bio-compatibilities compared to other nanocarriers. The adsorption of cisplatin on the surface of biphenylene involves charge transfer from cisplatin to biphenylene. The drug is shown to be released at body temperature in an acidic environment. Biphenylene also exhibits excellent cytotoxicity activity and cellular uptake of the drug. Overall, biphenylene shows promise as a potential nanocarrier for cisplatin delivery.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Hyun Jeong, Hyeong Chan Suh, Ga Hyun Cho, Rafael Salas-Montiel, Hayoung Ko, Ki Kang Kim, Mun Seok Jeong
Summary: In this study, a potential platform to enhance Raman scattering and increase the number of observable Raman modes in monolayer transition metal dichalcogenides (TMDs) was proposed. The platform consisted of large-scale arrays of gold micropillars (MPs), which were able to enhance the Raman intensity of TMDs and make difficult-to-detect Raman modes observable. The platform showed great industrial advantages and wide applicability due to its low cost, simple process, large controllable area, and short process time.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Yasir Abbas, Shafqat Ali, Sajjad Ali, Waqar Azeem, Zareen Zuhra, Haoliang Wang, Mohamed Bououdina, Zhenzhong Sun
Summary: In this study, FeOx@SPNO-C core-shell nanospheres as a catalyst for degradation of sulfamethoxazole (SMX) were successfully synthesized. The synergistic interaction between FeOx and SPNO-C, high carbon charge density, and the presence of C = O groups and N/Fe-Nx sites were found to be key factors for the enhanced degradation of SMX.
APPLIED SURFACE SCIENCE
(2024)
Article
Chemistry, Physical
Qiaoting Yang, Yuxiao Gong, Yan Qian, Zhou-Qing Xiao, Serge Cosnier, Xue-Ji Zhang, Robert S. Marks, Dan Shan
Summary: This study proposes a hierarchical confinement strategy to design Prussian blue nanoparticles (PB NPs) with satisfactory electrocatalytic ability and stability. The catalytic synthesis of PB NPs is achieved through a hydrothermal process, and the as-prepared PB@NH2MIL exhibits efficient electronic transmission and enhanced electrocatalytic properties.
APPLIED SURFACE SCIENCE
(2024)