Rapid development of systemic insulin resistance with overeating is not accompanied by robust changes in skeletal muscle glucose and lipid metabolism

High muscle lipid content in obesity is not due to enhanced activation of key triglyceride esterification enzymes or the suppression of lipolytic proteins

(2011) Minghua Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Sixteen years and counting: an update on leptin in energy balance

(2011) Laurent Gautron et al.   JOURNAL OF CLINICAL INVESTIGATION

Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle

(2011) Umesh B. Masharani et al.   PLoS One

Inflammasome is a central player in the induction of obesity and insulin resistance

(2011) R. Stienstra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

(2011) N. Kumashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organ-specific dietary fatty acid uptake in humans using positron emission tomography coupled to computed tomography

(2010) Sébastien M. Labbé et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Short-Term Overfeeding May Induce Peripheral Insulin Resistance Without Altering Subcutaneous Adipose Tissue Macrophages in Humans

(2010) C. S. Tam et al.   DIABETES

Effects of short-term overfeeding with fructose, fat and fructose plus fat on plasma and hepatic lipids in healthy men

(2010) H. Sobrecases et al.   DIABETES & METABOLISM

A 2-wk reduction of ambulatory activity attenuates peripheral insulin sensitivity

(2010) Rikke Krogh-Madsen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Time-Resolved and Tissue-Specific Systems Analysis of the Pathogenesis of Insulin Resistance

(2010) Robert Kleemann et al.   PLoS One

Comparison of Noninvasive Markers of Fibrosis in Patients With Nonalcoholic Fatty Liver Disease

(2009) Amy G. Shah et al.   Clinical Gastroenterology and Hepatology

Skeletal Muscle Lipogenic Protein Expression Is Not Different between Lean and Obese Individuals: A Potential Factor in Ceramide Accumulation

(2009) A. Brianne Thrush et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Fasted to Fed Trafficking of Fatty Acids in Human Adipose Tissue Reveals a Novel Regulatory Step for Enhanced Fat Storage

(2009) Toralph Ruge et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Impact of short-term high-fat feeding on glucose and insulin metabolism in young healthy men

(2009) Charlotte Brøns et al.   JOURNAL OF PHYSIOLOGY-LONDON

Early responses of insulin signaling to high-carbohydrate and high-fat overfeeding

(2009) Rebecca L Adochio et al.   Nutrition & Metabolism

Liver, Muscle, and Adipose Tissue Insulin Action Is Directly Related to Intrahepatic Triglyceride Content in Obese Subjects

(2008) Kevin M. Korenblat et al.   GASTROENTEROLOGY

Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage

(2007) Ranganath Muniyappa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM