4.6 Article

Inertial modulation of hydrophoretic cell sorting and focusing

Journal

APPLIED PHYSICS LETTERS
Volume 104, Issue 7, Pages -

Publisher

AMER INST PHYSICS
DOI: 10.1063/1.4866045

Keywords

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Funding

  1. Pioneer Research Center Program through the National Research Foundation of Korea
  2. Ministry of Science, ICT & Future Planning [2013M3C1A3064777]
  3. National Research Foundation of Korea [2013K2A1A2053078]
  4. National Research Foundation of Korea [2013M3C1A3064777] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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This paper demonstrates a method of modulating hydrophoretic focusing and sorting by inertial forces in a microfluidic device. At low Reynolds number (Re), hydrophoresis enables size-based sorting by generating specific equilibrium positions for differently sized particles. As increasing Re, hydrophoresis becomes coupled with inertial effects that bias the equilibrium positions to create a narrow focusing stream. Using this method, we achieved both size-based sorting and sheathless focusing in a device. (C) 2014 AIP Publishing LLC.

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