Article
Biophysics
Liujing Zhuang, Xinwei Wei, Nan Jiang, Qunchen Yuan, Chunlian Qin, Deming Jiang, Mengxue Liu, Yanning Zhang, Ping Wang
Summary: The study introduces a biohybrid nose for evaluating malodor masking efficiency of perfumed products objectively and quantitatively. Results show that the masking efficiency of fragrance is concentration-dependent, with complete masking potentially occurring when fragrance is used at a concentration 2-3 orders of magnitude higher than malodor.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Biochemical Research Methods
Bo Yang, Ping Wang, Zhenqing Li, Qingxiang You, Shinichi Sekine, Junshan Ma, Songlin Zhuang, Dawei Zhang, Yoshinori Yamaguchi
Summary: A multiplex circular array shaped CF-PCR microfluidic chip was designed for on-site detection of bacteria. The chip consisted of 12 serpentine microchannels distributed on a disc, with each microchannel having an inlet and an outlet for sample injection and detection of PCR products based on fluorescence. By using a one-to-twelve diverter, samples could be simultaneously driven into each inlet. The system achieved simultaneous amplification of 12 different target genes and on-site detection of their corresponding positives within 23 minutes.
Article
Biophysics
Zhidian Diao, Xixian Wang, Jiaping Zhang, Anle Ge, Teng Xu, Lingyan Kan, Yuandong Li, Yuetong Ji, Xiaoyan Jing, Jian Xu, Bo Ma
Summary: Static droplet arrays are important for high-capacity screening assays, but extracting target droplets remains a challenge. This study presents an optical-based on-demand droplet release system using a 1064 nm laser to push out droplets. The system has a high success rate and low residual volume, making it suitable for high-throughput screening assays.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Engineering, Environmental
Bert Swart, Arto Pihlajamaki, Y. M. John Chew, Jannis Wenk
Summary: This study presents a batch flotation method to assess the removal of microplastics of different densities, sizes, and shapes. By using in-situ image analysis, particle shape, size, and concentration as well as particle-bubble interactions were measured and analyzed. The study provides important quantitative results on bubble-particle interaction for the selective removal of microplastics and presents a visualization method for tracking and characterizing micrometer-sized particles in solid-liquid-gas multiphase media.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Chemical
F. A. Hamad, Kul Pun, Basso Alessio, S. A. Najim, P. B. Ganesan, D. Hughes
Summary: The aim of this paper is to develop a low-cost, low-power consumption microbubble generator to improve gas-to-liquid mass transfer. Microbubble aeration is used in aquaculture, dissolved air flotation (DAF), oil refinement, and reducing skin friction on ship hull. Single Venturi and 3 twin-Venturis microbubble generators are manufactured and tested, showing that twin-Venturi generators produce smaller microbubbles with higher dissolved oxygen concentration and narrower size distribution, reducing the probability of bubbles coalescing.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Yuechen Liu, Chao Feng, Siyu Dong, Jingyuan Zhu, Zhanshan Wang, Xinbin Cheng
Summary: On-chip multi-dimensional detection systems integrating pixelated polarization and spectral filter arrays are a promising trend for optical detection instruments in medical imaging and remote sensing. However, there is usually a trade-off between the detection dimension, optical efficiency, and spectral resolution in thin-film or microstructure-based filter arrays. In this study, we demonstrate a novel on-chip integrated polarization spectral detection filter arrays using metasurfaces and multilayer films, which exhibit high spectral resolution and optical efficiency.
Article
Chemistry, Analytical
Yang Lu, Changbiao Zhan, Liandong Yu, Yiyue Yu, Huakun Jia, Xiaozhe Chen, Dongzhi Zhang, Rongke Gao
Summary: We developed a novel multifunctional nanocone array as a solid immunoassay plate and SERS substrate for the simultaneous detection of PSA and thrombin based on a microfluidic chip. Compared to traditional immunoassays, this nanocone array with a deposited gold film provides a larger surface area for efficient target antigen capture. By integrating this microfluidic chip, we achieved simultaneous detection of PSA and thrombin with high sensitivity. This detection strategy shows great potential for early prostate cancer diagnosis.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Biochemical Research Methods
Vinit Kumar Yadav, Preetha Ganguly, Prashant Mishra, Samaresh Das, Dhiman Mallick
Summary: This study developed a versatile magnetic microfluidic device for concentration-dependent compartmentalization of a magnetically controlled anticancer drug. By optimizing the microfluidic design and magnet configuration, predictable concentration control and gradient generation were achieved. The results of drug screening and cytotoxicity testing using the device were consistent with traditional methods.
Article
Biochemical Research Methods
Kirill Kolesnik, Philipp Segeritz, Daniel J. Scott, Vijay Rajagopal, David J. Collins
Summary: Acoustofluidic devices can manipulate particles and cells in arbitrary configurations at the microscale without complex patterning. This approach is enabling for cell studies and tissue engineering applications.
Article
Nanoscience & Nanotechnology
Zhizhang Wang, Jitao Ji, Xin Ye, Yuxin Chen, Xueyun Li, Wange Song, Bin Fang, Ji Chen, Shining Zhu, Tao Li
Summary: This study proposes a miniaturized compact strategy to enlarge the beam steering angle in optical phased array (OPA) by integrating a metasurface-doublet with a port-selected OPA. The metasurface-doublet, composed of convex and concave metalenses with quadratic phase distribution, is precisely fabricated layer by layer on the OPA chip, which is made of Lithium Niobate on Insulator (LNOI). Experimental results show that the proposed method achieves 1.54 times FOV amplification in the horizontal direction with > 41% working efficiency. This research provides a feasible approach for wide-angle beam steering and a powerful platform for developing integrated multilayer metasurface devices.
Article
Medicine, Research & Experimental
Hanna Bendjador, Josquin Foiret, Robert Wodnicki, Douglas N. Stephens, Zoe Krut, Eun-Yeong Park, Zulma Gazit, Dan Gazit, Gadi Pelled, Katherine W. Ferrara
Summary: The researchers propose a system for performing and monitoring microbubble-based therapy, capable of volumetric imaging over a large field-of-view. By designing and testing a unique array and system, they demonstrate the ability to guide microbubble-based therapeutic protocols in three dimensions using ultrasound.
Article
Chemistry, Analytical
Haiying Shen, Lianhua Dong, Yunhua Gao, Xia Wang, Xinhua Dai
Summary: In this study, a highly integrated microfluidic chip for nucleic acid extraction, amplification, and detection was designed. A hand-held device with precise temperature control and high-quality imaging was developed for experiment and data analysis. The chip allows for mobile point-of-care testing via wireless communication with a smartphone. The results show the potential of this platform for nucleic acid detection.
ANALYTICAL CHEMISTRY
(2023)
Article
Optics
Shuiying Xiang, Yuechun Shi, Xingxing Guo, Yahui Zhang, Hongji Wang, Dianzhuang Zheng, Ziwei Song, Yanan Han, Shuang Gao, Shihao Zhao, Biling Gu, Hailing Wang, Xiaojun Zhu, Lianping Hou, Xiangfei Chen, Wanhua Zheng, Xiaohua Ma, Yue Hao
Summary: Photonic neuromorphic computing is a promising approach for low-latency and energy-efficient computing systems. A photonic spiking neural network (PSNN) utilizes brain-like spatiotemporal processing for high-performance neuromorphic computing. However, the nonlinear computation of a PSNN remains challenging. In this study, a photonic spiking neuron chip based on an integrated Fabry-Perot laser with a saturable absorber (FP-SA) is proposed and fabricated. It demonstrates the nonlinear dynamics of a neuron-like system and serves as a fundamental building block for constructing the PSNN hardware. Time-multiplexed temporal spike encoding is proposed to surpass the hardware integration scale limit and enable functional PSNNs. Experimental results show that PSNNs with single or cascaded photonic spiking neurons can perform classification tasks using a supervised learning algorithm, paving the way for multilayer PSNNs to handle complex tasks.
Article
Engineering, Electrical & Electronic
Ming Xu, Liang Chen, Hao Shi, Zhu Yang, Jiahao Li, Teng Long
Summary: This article proposes an FPGA-based implementation of ship detection for on-board processing, which achieves high efficiency and reduces resource consumption through clustering and data-buffering cycle optimization.
IEEE JOURNAL OF SELECTED TOPICS IN APPLIED EARTH OBSERVATIONS AND REMOTE SENSING
(2022)
Article
Optics
Mathias Prost, Jon Oyvind Kjellman, Sarvagya Dwivedi, Aleksandrs Marinins, Hemant Kumar Tyagi, Tangla David Kongnyuy, Philippe Soussan, Marcus S. Dahlem, Xavier Rottenberg, Roelof Jansen
Summary: This paper demonstrates an on-chip integrated phase calibration system for optical phased arrays (OPAs), which includes compact phase interrogator structures and readout photodiodes. The calibration enables high-fidelity beam steering and arbitrary pattern generation.
Article
Thermodynamics
T. I. Farouk, Y. Xu, C. T. Avedisian, F. L. Dryer
PROCEEDINGS OF THE COMBUSTION INSTITUTE
(2017)
Editorial Material
Gastroenterology & Hepatology
Judy A. Trieu, Mohammad Bilal, Ali Hashmi
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2018)
Article
Substance Abuse
Deborah Garnick, Constance Horgan, Tami L. Mark, Margaret Lee, Andrea Acevedo, Sarah Neager, Peggy O'Brien, Ali Hashmi, Bill Marder, Kay Miller
Article
Energy & Fuels
Yuhao Xu, Jordan D. Brunson, C. Thomas Avedisian, Yiren Shen, Ivan Keresztes, Anthony M. Condo, Daniel Phillips
Article
Chemistry, Physical
Qian Chen, Qingyuan Ding, Yitian Wang, Yuhao Xu, Jinlan Wang
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)
Article
Thermodynamics
Yuhao Xu, Tanvir Farouk, Michael C. Hicks, C. Thomas Avedisian
COMBUSTION AND FLAME
(2020)
Article
Biology
Ali Hashmi, Sham Tlili, Pierre Perrin, Molly Lowndes, Hanna Peradziryi, Joshua M. Brickman, Alfonso Martinez Arias, Pierre-Francois Lenne
Summary: Shaping the animal body plan involves complex processes of spatial organization and patterning of different germ layers. This study focuses on the formation of the endoderm using gastruloids, 3D aggregates of mouse embryonic stem cells. The researchers discovered a three-step mechanism leading to the generation of the endoderm, involving the loss of E-cadherin contacts, separation of cell populations, and differentiation. Interestingly, the endoderm formation does not require an epithelial-to-mesenchymal transition, but instead relies on the maintenance of an epithelial state and fragmentation of E-cadherin contacts. This study highlights the importance of signaling and tissue flows in establishing the body plan.
Article
Materials Science, Multidisciplinary
Yitian Wang, Xuehao Tang, Qionghua Zhou, Xinyu Chen, Qian Chen, Yuhao Xu
Article
Medicine, General & Internal
Rubbia Nawaz, Muhammad Azeem, Ali Abbas Hashmi, Hafiz Shaker Mahmood, Muhammad Husnain Akram, Muhammad Moazzam
PAKISTAN JOURNAL OF MEDICAL & HEALTH SCIENCES
(2018)
Meeting Abstract
Gastroenterology & Hepatology
Hamzeh A. Saraireh, Muhannad Al Hanayneh, Ali Hashmi
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2017)
Meeting Abstract
Gastroenterology & Hepatology
Thanh-Truc Le, Mohammad Bilal, Ali Hashmi
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2017)
Meeting Abstract
Gastroenterology & Hepatology
Thanh-Truc Le, Eric Gou, Mohammad Bilal, Ali Hashmi
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2017)
Meeting Abstract
Gastroenterology & Hepatology
Kevin Kline, Eric Gou, Mohammad Bilal, Ali Hashmi, Laila Rashidi
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2017)
Letter
Gastroenterology & Hepatology
Thanh-Truc Le, Mohammad Bilal, Ali Hashmi, Sreeram Parupudi
DIGESTIVE AND LIVER DISEASE
(2017)
Letter
Gastroenterology & Hepatology
Ashish Mamachen, Muhannad Al-Hanayneh, Mohammad Bilal, Shehzad Merwat, Ali Hashmi
DIGESTIVE AND LIVER DISEASE
(2017)
