Article
Chemistry, Physical
Zhen-Fei Tian, Jing-Xuan Pei, Xiang Yu, Yi-Bo Sun, Lei Yang
Summary: By fabricating a core-shell structured Ag@ZnS hybrid as a SERS substrate, the monitoring and prevention of 4-ATP pollution can be achieved with high sensitivity and superior reproducibility.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Physical
Jiaxi Sui, Dongdong Liu, Chunyu Wa, Lijuan Wang, Bo Zhong, Yuanyuan Ma
Summary: A sea urchin-like K2Ti8O17 (KTO) nanomaterial was prepared by a facile hydrothermal method and showed excellent potential as a non-metallic SERS substrate for dye detection in the environment. The sea urchin-like KTO exhibited enhancement factors of 3.8 x 105 and 2.45 x 105 for crystal violet and methylene blue, respectively, with minimum detection limits of 10-8 M. The superior SERS performance of the sea urchin-like KTO was attributed to its excellent charge transfer and probe adsorption capability, as confirmed by energy band and zeta potential analysis. The practical application potential of the sea urchin-like KTO was further demonstrated through scenario simulation.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Biotechnology & Applied Microbiology
Zhouyang Xiang, Mengyun He, Li Li, Jamshed Bobokalonov, Abduvali Dzhonmurodov, Xingxiang Ji
Summary: In this study, a paper-based Au-Ag bimetallic SERS substrate was developed using cellulose fiber/paper-based technology. The substrate, anchored by natural macromolecule-xylan, showed high Raman enhancement performance and reproducibility. It can be used for rapid detection of agricultural product contaminants and pesticide residues on fruit surfaces.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Nanoscience & Nanotechnology
Engin Er, Ana Sanchez-Iglesias, Alessandro Silvestri, Blanca Arnaiz, Luis M. Liz-Marzan, Maurizio Prato, Alejandro Criado
Summary: Early detection of cancer biomarkers is crucial for effective diagnosis and treatment of cancer. A sandwich immunoassay based on SERS technology was developed for the ultrasensitive detection of alpha-fetoprotein as a biomarker for early-stage hepatocellular carcinoma, showing promising potential for clinical applications in early cancer detection.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Nanoscience & Nanotechnology
Yaning Zhou, Haizi Yao, Chundong Liu, Mengyu Chen, Chao Zhang, Mei Liu, Jian Wang, Fujun Zhang, Jing Yu, Baoyuan Man, Qianqian Sun
Summary: The study introduced micrometer-scale grating structure and nanometer-scale zinc oxide nano spikes into the SERS substrate, forming an optimized multiscale 3D structure with high sensitivity and enhancement factor for Rhodamine 6G as the probe molecule.
Article
Spectroscopy
Mohammad Kamal Hossain, Qasem Ahmed Drmosh
Summary: Plasmonic nanostructures, particularly irregular surfaces of silver nanorings, have shown promise in surface-enhanced Raman scattering (SERS) spectroscopy. Through the fabrication and characterization of clusters-based Ag nanorings, it was found that they could achieve SERS enhancement factors as high as 2.1 x 10^4. By simulating EM near-field distributions and investigating the irregular shapes and arrangements of clusters within the nanorings, a deeper understanding of the underlying EM mechanism in SERS enhancements was gained.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Biophysics
S. Spaziani, G. Quero, S. Manago, G. Zito, D. Terracciano, P. E. Macchia, F. Galeotti, M. Pisco, A. C. De Luca, A. Cusano
Summary: We developed an immunoassay platform for the detection of human Thyroglobulin (Tg) in thyroid cancer patients with lymph node metastases. The platform utilizes a self-assembled surface-enhanced Raman scattering (SERS) substrate and functionalized gold nanoparticles to enhance molecular specificity and signal amplification. The platform has a low detection limit of 7 pg/mL and has been successfully applied to washout fluids from fine needle aspiration biopsies in cancer patients, demonstrating its high specificity in complex biological matrices.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Materials Science, Multidisciplinary
Shuang Xiong, Dalei Wang, Hangkai Qiu, Tao He, Chao Wang, Yueyue Wang, Chaoqing Dai, Wei Liu
Summary: The overuse of mixed pesticides poses a threat to the ecosystem and human health, and current pesticide detection methods are complex. This study developed a Ti3C2Tx-noble metal hybrid flexible substrate for efficient trace detection of pesticide residues. The substrate showed ultra-high sensitivity and a low limit of detection, and it was able to detect pesticide concentrations lower than the EU permissible limits. This high performance substrate offers a great advantage in the trace detection of molecules.
MATERIALS & DESIGN
(2023)
Article
Chemistry, Physical
Qingyuan Ma, Ken Minoshima, Satoru Shoji
Summary: Surface-enhanced Raman scattering (SERS) can greatly improve molecule sensitivity. The fabrication of glass microcapillary tubes decorated with silver nanoparticles allows efficient excitation and detection of SERS. The tubes not only serve as sample containers but also act as optical waveguides to guide the excitation laser light and SERS light.
JOURNAL OF PHYSICAL CHEMISTRY A
(2022)
Article
Chemistry, Multidisciplinary
Shiyu Sun, Jingying Zheng, Ruihao Sun, Dan Wang, Guanliang Sun, Xingshuang Zhang, Hongyu Gong, Yong Li, Meng Gao, Dongwei Li, Guanchen Xu, Xiu Liang
Summary: Defect-containing monolayer MoS2 with abundant density of states and effective photoinduced charge transfer resonance becomes a promising and versatile substrate capable of detecting a wide range of dye molecules and enhancing Raman enhancement.
Article
Materials Science, Multidisciplinary
Miao Yu, Qihang Tian, Guangyuan He, Kaimin Cui, Jihong Zhang
Summary: Surface-enhanced Raman scattering (SERS) is a novel method for low concentration molecular detection, and tapered fiber SERS probes based on silver nanocubes exhibit high sensitivity. These probes can be used for both qualitative and quantitative analysis, with an optimal cone angle of 8.3 degrees.
ADVANCED FIBER MATERIALS
(2021)
Article
Chemistry, Analytical
Li Guo, Jing Huang, Yaxin Chen, Bohan Zhang, Minbiao Ji
Summary: In this study, metal-lined hollow-core fiber (MLHCF) was used to improve the sensitivity of stimulated Raman scattering (SRS) in sensing dilute solutions. By extending the light-matter interaction volume, MLHCF showed significant enhancement and suppressed cross-phase modulation (XPM) background at a certain fiber length. The fiber-enhanced SRS (FE-SRS) method has potential in sensitive detection of molecules in solution and gas phases.
Article
Chemistry, Analytical
Zhe Zhang, Shen Jiang, Xiaotong Wang, Tuo Dong, Yunpeng Wang, Dan Li, Xin Gao, Zhangyi Qu, Yang Li
Summary: This study presents a novel enhanced substrate for label-free detection of respiratory viruses using surface-enhanced Raman Scattering. The method involves the use of sodium borohydride to reduce silver ions, eliminating the disorganized peak signal of traditional reducing agents. The study successfully obtained the fingerprints and concentration-dependent curves of various respiratory viruses, including SARS-CoV-2, and identified them in serum and saliva within two minutes using linear discriminant diagnostic analysis. This enhanced substrate is therefore highly valuable for the global response to the COVID-19 pandemic.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Chemistry, Multidisciplinary
Wenbing Li, Xin Tong, Zhuo Yang, Jiali Zhang, Bo Liu, Chao Ping Chen
Summary: Surface-enhanced Raman scattering (SERS) has attracted significant attention as a high sensitivity analytical method for molecule detection. This study compared the performance of AuNP/SiO2/Au/Sapphire substrate and AuNP/Si substrate in detecting molecules in Raman microscopy, with the former demonstrating improved sensitivity. Simulation using the finite-difference time-domain (FDTD) method provided insights into the enhanced sensitivity of the AuNP/SiO2/Au/Sapphire substrate, suggesting optimized parameters for further research.
Article
Biochemistry & Molecular Biology
Yinglin Luo, Lida Xing, Chuanshuang Hu, Weiwei Zhang, Xiuyi Lin, Jin Gu
Summary: Cu2O/Ag heterostructures were successfully synthesized and used for surface-enhanced Raman scattering (SERS) analysis to detect methylene blue. The results showed that the Cu2O/Ag heterostructures had high enhancement effect and good detection performance at low concentrations.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)