Engineering and Kinetic Stabilization of the Therapeutic Enzyme Anabeana variabilis Phenylalanine Ammonia Lyase

Rational Introduction of Disulfide Bond to Enhance Optimal Temperature of Lipomyces starkeyi α-Dextranase Expressed in Pichia pastoris

(2013) Lin Chen   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Effect of Ion Pair on Thermostability of F1 Protease: Integration of Computational and Experimental Approaches

(2012) Raja Noor Zaliha Raja Abd Rahman   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

A Study on the Effect of Surface Lysine to Arginine Mutagenesis on Protein Stability and Structure Using Green Fluorescent Protein

(2012) Sriram Sokalingam et al.   PLoS One

A graphical interface for the FoldX forcefield

(2011) J. Van Durme et al.   BIOINFORMATICS

Contribution of Hydrophobic Interactions to Protein Stability

(2011) C. Nick Pace et al.   JOURNAL OF MOLECULAR BIOLOGY

Stabilizing Salt-Bridge Enhances Protein Thermostability by Reducing the Heat Capacity Change of Unfolding

(2011) Chi-Ho Chan et al.   PLoS One

Contributions of aromatic pairs to the folding and stability of long-lived human γD-crystallin

(2011) Fanrong Kong et al.   PROTEIN SCIENCE

Widespread Disulfide Bonding in Proteins from Thermophilic Archaea

(2011) Julien Jorda et al.   ARCHAEA-AN INTERNATIONAL MICROBIOLOGICAL JOURNAL

Protein kinetic stability

(2010) Jose M. Sanchez-Ruiz   BIOPHYSICAL CHEMISTRY

Enhanced thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 by rational engineering of a glycine to proline mutation

(2010) Jian Tian et al.   FEBS Journal

Enhancing the thermostability of α-glucosidase from Thermoanaerobacter tengcongensis MB4 by single proline substitution

(2010) Cheng Zhou et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Advances and challenges in phenylketonuria

(2010) Cary O. Harding et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Phenylketonuria

(2010) Nenad Blau et al.   LANCET

Design and introduction of a disulfide bridge in firefly luciferase: increase of thermostability and decrease of pH sensitivity

(2010) Mehdi Imani et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

An additional aromatic interaction improves the thermostability and thermophilicity of a mesophilic family 11 xylanase: Structural basis and molecular study

(2010) Jacques Georis et al.   PROTEIN SCIENCE

Enhancing thermostability of a Rhizomucor miehei lipase by engineering a disulfide bond and displaying on the yeast cell surface

(2009) Zhen-lin Han et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Converting an injectable protein therapeutic into an oral form: Phenylalanine ammonia lyase for phenylketonuria

(2009) Tse Siang Kang et al.   MOLECULAR GENETICS AND METABOLISM

Structural and Biochemical Characterization of the Therapeutic Anabaena variabilis Phenylalanine Ammonia Lyase

(2008) Lin Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Correction of Murine PKU Following AAV-mediated Intramuscular Expression of a Complete Phenylalanine Hydroxylating System

(2008) Zhaobing Ding et al.   MOLECULAR THERAPY

Thermodynamics of stacking interactions in proteins

(2008) Simone Marsili et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

Preclinical evaluation of multiple species of PEGylated recombinant phenylalanine ammonia lyase for the treatment of phenylketonuria

(2008) C. N. Sarkissian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Increasing protein stability using a rational approach combining sequence homology and structural alignment: Stabilizing the WW domain

(2002) Xin Jiang et al.   PROTEIN SCIENCE