Biosynthesis of Tropolones in Streptomyces spp.: Interweaving Biosynthesis and Degradation of Phenylacetic Acid and Hydroxylations on the Tropone Ring

Restored iron transport by a small molecule promotes absorption and hemoglobinization in animals

(2017) Anthony S. Grillo et al.   SCIENCE

Functional Genome Mining for Metabolites Encoded by Large Gene Clusters through Heterologous Expression of a Whole-Genome Bacterial Artificial Chromosome Library in Streptomyces spp.

(2016) Min Xu et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Hybrubins: Bipyrrole Tetramic Acids Obtained by Crosstalk between a Truncated Undecylprodigiosin Pathway and Heterologous Tetramic Acid Biosynthetic Genes

(2016) Zhilong Zhao et al.   ORGANIC LETTERS

Novel α-substituted tropolones promote potent and selective caspase-dependent leukemia cell apoptosis

(2016) Jin Li et al.   PHARMACOLOGICAL RESEARCH

Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens

(2016) Rurun Wang et al.   mBio

Non-enzymatic pyridine ring formation in the biosynthesis of the rubrolone tropolone alkaloids

(2016) Yijun Yan et al.   Nature Communications

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Volatiles from nineteen recently genome sequenced actinomycetes

(2015) Christian A. Citron et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Biosynthesis of the antibiotic tropodithietic acid by the marine bacterium Phaeobacter inhibens

(2014) Nelson L. Brock et al.   CHEMICAL COMMUNICATIONS

The biology and synthesis of α-hydroxytropolones

(2014) Christine Meck et al.   MedChemComm

Chemical mechanisms involved during the biosynthesis of tropolones

(2013) Russell J Cox et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Menaquinone Biosynthesis: Formation of Aminofutalosine Requires a Unique Radical SAM Enzyme

(2013) Nilkamal Mahanta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

High-Throughput Screening for Streptomyces Antibiotic Biosynthesis Activators

(2012) Li Chen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genetic, molecular, and biochemical basis of fungal tropolone biosynthesis

(2012) J. Davison et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Studies on the Mechanism of Ring Hydrolysis in Phenylacetate Degradation

(2011) Robin Teufel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bacterial phenylalanine and phenylacetate catabolic pathway revealed

(2010) R. Teufel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Engineering Streptomyces coelicolor for heterologous expression of secondary metabolite gene clusters

(2010) Juan Pablo Gomez-Escribano et al.   Microbial Biotechnology

Identification and biosynthesis of tropone derivatives and sulfur volatiles produced by bacteria of the marine Roseobacter clade

(2009) Verena Thiel et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

The Mildiomycin Biosynthesis: Initial Steps for Sequential Generation of 5-Hydroxymethylcytidine 5′-Monophosphate and 5-Hydroxymethylcytosine inStreptoverticillium rimofaciensZJU5119

(2008) Li Li et al.   CHEMBIOCHEM

Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism

(2008) S. G. Van Lanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deciphering the genetic determinants for aerobic nicotinic acid degradation: The nic cluster from Pseudomonas putida KT2440

(2008) J. I. Jimenez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A fresh look at natural tropolonoids

(2007) Ronald Bentley   NATURAL PRODUCT REPORTS