4.6 Article

The ygaVP genes of Escherichia coli form a tributyltin-inducible operon

Journal

APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 74, Issue 6, Pages 1954-1958

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02294-07

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A tributyltin (TBT) luxAB transcriptional fusion in Escherichia coli revealed that a TBT-activated promoter is located upstream of two cotranscribed orphan genes, ygaV and ygaP. We demonstrate that transcription from the promoter upstream of ygaVP is constitutive in a ygaVP mutant, suggesting that YgaV is an autoregulated, TBT-inducible repressor.

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