N-(3-oxo-acyl) homoserine lactone induced germ cell apoptosis and suppressed the over-activated RAS/MAPK tumorigenesis via mitochondrial-dependent ROS in C. elegans

Perfluorooctane sulfonate exposure causes gonadal developmental toxicity in Caenorhabditis elegans through ROS-induced DNA damage

(2016) Xiaoying Guo et al.   CHEMOSPHERE

Shengmai Formula suppressed over-activated Ras/MAPK pathway in C. elegans by opening mitochondrial permeability transition pore via regulating cyclophilin D

(2016) Yan Liu et al.   Scientific Reports

Endosulfan Isomers and Sulfate Metabolite Induced Reproductive Toxicity in Caenorhabditis elegans Involves Genotoxic Response Genes

(2015) Hua Du et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Reproductive Toxicity of Endosulfan: Implication From Germ Cell Apoptosis Modulated by Mitochondrial Dysfunction and Genotoxic Response Genes inCaenorhabditis elegans

(2015) Hua Du et al.   TOXICOLOGICAL SCIENCES

Cell cultures in drug development: Applications, challenges and limitations

(2015) Abdelaziz Ghanemi   SAUDI PHARMACEUTICAL JOURNAL

Bacterial Quorum Sensing Molecule N-3-Oxo-Dodecanoyl-L-Homoserine Lactone Causes Direct Cytotoxicity and Reduced Cell Motility in Human Pancreatic Carcinoma Cells

(2014) Ashwath S. Kumar et al.   PLoS One

The Clinical Relevance of Cancer Cell Lines

(2013) J.-P. Gillet et al.   JNCI-Journal of the National Cancer Institute

Oxidative Stress and Mitogen-Activated Protein Kinase Pathways Involved in Cadmium-Induced BRL 3A Cell Apoptosis

(2013) Zhang Yiran et al.   Oxidative Medicine and Cellular Longevity

Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits

(2013) Gordon F. Rushworth et al.   PHARMACOLOGY & THERAPEUTICS

Pseudomonas aeruginosa biofilm-associated homoserine lactone C12 rapidly activates apoptosis in airway epithelia

(2012) Christian Schwarzer et al.   CELLULAR MICROBIOLOGY

Iron induces hepatocytes death via MAPK activation and mitochondria-dependent apoptotic pathway: Beneficial role of glycine

(2012) Sudip Bhattacharyya et al.   FREE RADICAL RESEARCH

DNA damage by reactive species: Mechanisms, mutation and repair

(2012) N R Jena   JOURNAL OF BIOSCIENCES

Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress

(2011) A. T. Shaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reactive oxygen species, cellular redox systems, and apoptosis

(2010) Magdalena L. Circu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development

(2009) S. Arur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How mitochondria produce reactive oxygen species

(2008) Michael P. Murphy   BIOCHEMICAL JOURNAL

Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

(2008) Maxwell C. K. Leung et al.   TOXICOLOGICAL SCIENCES