Pifithrin-α provides neuroprotective effects at the level of mitochondria independently of p53 inhibition

3-Hydroxybutyrate methyl ester as a potential drug against Alzheimer's disease via mitochondria protection mechanism

(2013) Junyu Zhang et al.   BIOMATERIALS

A neuroprotective phase precedes striatal degeneration upon nucleolar stress

(2013) G Kreiner et al.   CELL DEATH AND DIFFERENTIATION

Pifithrin-α, a pharmacological inhibitor of p53, downregulates lipopolysaccharide-induced nitric oxide production via impairment of the MyD88-independent pathway

(2013) Adilsaikhan Mendjargal et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

p53 in neurodegenerative diseases and brain cancers

(2013) Frédéric Checler et al.   PHARMACOLOGY & THERAPEUTICS

p53 Opens the Mitochondrial Permeability Transition Pore to Trigger Necrosis

(2012) Angelina V. Vaseva et al.   CELL

Inhibition of Drp1 provides neuroprotection in vitro and in vivo

(2012) J Grohm et al.   CELL DEATH AND DIFFERENTIATION

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

Involvement of activation of PI3K/Akt pathway in the protective effects of puerarin against MPP+-induced human neuroblastoma SH-SY5Y cell death

(2012) Guoqi Zhu et al.   NEUROCHEMISTRY INTERNATIONAL

Physical exercise as a possible strategy for brain protection: Evidence from mitochondrial-mediated mechanisms

(2012) Inês Marques-Aleixo et al.   PROGRESS IN NEUROBIOLOGY

Targeting the p53 pathway to protect the neonatal ischemic brain

(2011) Cora H. Nijboer et al.   ANNALS OF NEUROLOGY

Silibinin Activated p53 and Induced Autophagic Death in Human Fibrosarcoma HT1080 Cells via Reactive Oxygen Species-p38 and c-Jun N-Terminal Kinase Pathways

(2011) Wen-Jun Duan et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Enhanced Survival of Dopaminergic Neuronal Transplants in Hemiparkinsonian Rats by the p53 Inactivator PFT-α

(2011) J. Chou et al.   CELL TRANSPLANTATION

Nucleolar Disruption in Dopaminergic Neurons Leads to Oxidative Damage and Parkinsonism through Repression of Mammalian Target of Rapamycin Signaling

(2011) C. Rieker et al.   JOURNAL OF NEUROSCIENCE

Impedance measurement for real time detection of neuronal cell death

(2011) S. Diemert et al.   JOURNAL OF NEUROSCIENCE METHODS

Bid-mediated mitochondrial damage is a key mechanism in glutamate-induced oxidative stress and AIF-dependent cell death in immortalized HT-22 hippocampal neurons

(2010) S Tobaben et al.   CELL DEATH AND DIFFERENTIATION

Transcriptional Regulation by P53

(2010) R. Beckerman et al.   Cold Spring Harbor Perspectives in Biology

Bid mediates fission, membrane permeabilization and peri-nuclear accumulation of mitochondria as a prerequisite for oxidative neuronal cell death

(2009) Julia Grohm et al.   BRAIN BEHAVIOR AND IMMUNITY

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Reduced hippocampal damage and epileptic seizures after status epilepticus in mice lacking proapoptotic Puma

(2009) Tobias Engel et al.   FASEB JOURNAL

Cytoplasmic functions of the tumour suppressor p53

(2009) Douglas R. Green et al.   NATURE

Mitochondrial membrane permeabilization in neuronal injury

(2009) Lorenzo Galluzzi et al.   NATURE REVIEWS NEUROSCIENCE

Arginine methylation regulates the p53 response

(2008) Martin Jansson et al.   NATURE CELL BIOLOGY

Potential Role of PUMA in Delayed Death of Hippocampal CA1 Neurons After Transient Global Cerebral Ischemia

(2008) Kuniyasu Niizuma et al.   STROKE