Knockdown of BDNF suppressed invasion of HepG2 and HCCLM3 cells, a mechanism associated with inactivation of RhoA or Rac1 and actin skeleton disorganization

Brain-derived neurotrophic factor expression predicts adverse pathological & clinical outcomes in human breast cancer

(2011) Neill Patani et al.   Cancer Cell International

mTORC1 and mTORC2 Regulate EMT, Motility, and Metastasis of Colorectal Cancer via RhoA and Rac1 Signaling Pathways

(2011) P. Gulhati et al.   CANCER RESEARCH

Brain-Derived Neurotrophic Factor Promotes Tumorigenesis via Induction of Neovascularization: Implication in Hepatocellular Carcinoma

(2011) C.-T. Lam et al.   CLINICAL CANCER RESEARCH

Brain-Derived Neurotrophic Factor and Neurotrophin-4/5 Are Expressed in Breast Cancer and Can Be Targeted to Inhibit Tumor Cell Survival

(2011) E. Vanhecke et al.   CLINICAL CANCER RESEARCH

More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells

(2011) Dawei Guo et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Overexpression of TrkB promotes the progression of colon cancer

(2010) YINGJIAO YU et al.   APMIS

TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells

(2010) Siyang Zhang et al.   BMC CANCER

Inhibition of Tumor Cell Migration and Invasion Through Knockdown of Rac1 Expression in Medulloblastoma Cells

(2010) Baodong Chen et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Transducer of Cdc42-dependent Actin Assembly Promotes Epidermal Growth Factor-induced Cell Motility and Invasiveness

(2010) Jinghui Hu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma

(2010) M E Kupferman et al.   ONCOGENE

Trk Receptor Expression and Inhibition in Neuroblastomas

(2009) G. M. Brodeur et al.   CLINICAL CANCER RESEARCH

Brain-Derived Neurotrophic Factor Inhibits Phenylalanine-Induced Neuronal Apoptosis by Preventing RhoA Pathway Activation

(2009) Yongjun Zhang et al.   NEUROCHEMICAL RESEARCH

Up-regulation of Tropomyosin related kinase B contributes to resistance to detachment-induced apoptosis in hepatoma multicellular aggregations

(2008) Zhiyong Zhang et al.   MOLECULAR BIOLOGY REPORTS

Overexpression of Tyrosine Kinase B Protein as a Predictor for Distant Metastases and Prognosis in Gastric Carcinoma

(2008) Yong Zhang et al.   ONCOLOGY