☆ 3.9 Article

Relationship Between the Neutrophil to Lymphocyte Ratio and Parathyroid Adenoma Size in Patients With Primary Hyperparathyroidism

INTERNATIONAL SURGERY (2015)

Journal

INTERNATIONAL SURGERY

Volume 100, Issue 7-8, Pages 1185-1189

Publisher

INT COLLEGE OF SURGEONS

DOI: 10.9738/INTSURG-D-15-00044.1

Keywords

Neutrophil; Lymphocyte; Parathyroid adenoma; Primary hyperparathyroidism

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Surgery

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Abstract

The aim of our study was to evaluate the relationship between neutrophil to lymphocyte ratio (NLR) and adenoma size in parathyroidectomized patients who underwent a parathyroidectomy. The neutrophil to lymphocyte ratio has recently become popular as a biomarker for malignant diseases or for estimating tumor size preoperatively. This study aimed to estimate the relationship between adenoma size and NLR. Furthermore, we assessed whether a higher level of NLR is correlated with the presence of parathyroid carcinoma. A retrospective chart review was performed for patients with parathyroid adenoma who underwent parathyroidectomy between January 2012 and August 2014. Data related to age, sex, NLR, parathyroid hormone level (PTH), preoperative calcium, phosphorus, adenoma size, and pathology reports were collected. The neutrophil to lymphocyte ratio was significantly correlated with calcium levels, PTH levels, parathyroid adenoma size, and the presence of cancer. However, there was no correlation between NLR and age, sex, and phosphorus levels. This study is the first to document a positive correlation between NLR and parathyroid adenoma size, as well as the presence of cancer, in patients who underwent surgery as a result of primary hyperparathyroidism.

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Article Medicine, General & Internal

Elective surgery system strengthening: development, measurement, and validation of the surgical preparedness index across 1632 hospitals in 119 countries

James C. Glasbey, Tom E. F. Abbott, Adesoji Ademuyiwa, Adewale Adisa, Ehab AlAmeer, Sattar Alshryda, Alexis P. Arnaud, Brittany Bankhead-Kendall, M. K. Abou Chaar, Daoud Chaudhry, Ainhoa Costas-Chavarri, Miguel F. Cunha, Justine I. Davies, Anant Desai, Muhammed Elhadi, Marco Fiore, J. Edward Fitzgerald, Maria Fourtounas, Alex James Fowler, Kay Futaba, Gaetano Gallo, Dhruva Ghosh, Rohan R. Gujjuri, Rebecca Hamilton, Parvez Haque, Ewen M. Harrison, Peter Hutchinson, Gabriella Hyman, Arda Isik, Umesh Jayarajah, Haytham M. A. Kaafarani, Bryar Kadir, Ismail Lawani, Hans Lederhuber, Elizabeth Li, Markus W. Loffler, Maria Aguilera Lorena, Harvinder Mann, Janet Martin, Dennis Mazingi, Craig D. McClain, Kenneth A. McLean, John G. Meara, Antonio Ramos-De La Medina, Mengistu Mengesha, Ana Minaya, Maria Marta Modolo, Rachel Moore, Dion Morton, Dmitri Nepogodiev, Faustin Ntirenganya, Francesco Pata, Rupert Pearse, Maria Picciochi, Thomas Pinkney, Peter Pockney, Gabrielle H. van Ramshorst, Toby Richards, April Camilla Roslani, Sohei Satoi, Raza Sayyed, Richard Shaw, Joana Filipa Ferreira Simoes, Neil Smart, Richard Sulliva, Malin Sund, Sudha Sundar, Stephen Tabiri, Elliott H. Taylor, Mary L. Venn, Dakshitha Wickramasinghe, Naomi Wright, Sebastian Bernardo Shu Yip, Aneel Bhangu

Summary: This study developed and validated a novel index (SPI) to support the strengthening of local elective surgical systems and address growing backlogs. The findings showed that hospitals with a higher SPI were associated with an increased planned surgical volume ratio, independent of income status, COVID-19 burden, and hospital type. Annual self-assessment of surgical preparedness is recommended to identify areas for improvement and enhance the resilience of local surgical systems.

LANCET (2022)

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Article Emergency Medicine

Diagnostic Accuracy Rates of Appendicitis Scoring Systems for the Stratified Age Groups

Emre Gonullu, Zulfu Bayhan, Recayi Capoglu, Baris Mantoglu, Burak Kamburoglu, Tarik Harmantepe, Fatih Altintoprak, Unal Erkorkmaz

Summary: The predictive values of scoring systems for acute appendicitis vary in different age groups. Age should be considered when selecting a scoring system for patients with a prediagnosis of acute appendicitis. The Alvarado and Fenyo-Linberg scoring systems are the most accurate for the 18-45 and 46-65 age groups, respectively, while the Eskelinen scoring system is the most accurate for the >65 age group, but may not be suitable for use alone.

EMERGENCY MEDICINE INTERNATIONAL (2022)

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Article Surgery

Effects of cognitive status on outcomes of groin hernia repair using various anesthesia techniques

Recayi Capoglu, Murat Alemdar, Zulfu Bayhan, Emre Gonullu, Emrah Akin, Fatih Altintoprak, Ahmet Tarik Harmantepe, Furkan Kucuk, Hakan Demir, Bahaeddin Umur Aka

Summary: This study evaluated the effects of cognitive status on postoperative complication rates in patients undergoing groin hernia repair. The results showed that cognitive status did not significantly affect the complication rates, but may be related to prolonged hospitalization.

HERNIA (2023)

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Article Emergency Medicine

The ChoCO-W prospective observational global study: Does COVID-19 increase gangrenous cholecystitis?

Belinda De Simone, Fikri M. Abu-Zidan, Elie Chouillard, Salomone Di Saverio, Massimo Sartelli, Mauro Podda, Carlos Augusto Gomes, Ernest E. Moore, Susan J. Moug, Luca Ansaloni, Yoram Kluger, Federico Coccolini, Aitor Landaluce-Olavarria, Begona Estraviz-Mateos, Ana Uriguen-Etxeberria, Alessio Giordano, Alfonso Palmieri Luna, Luz Adriana Hernandez Amin, Adriana Maria Palmieri Hernandez, Amanda Shabana, Zakaria Andee Dzulkarnaen, Muhammad Asyraf Othman, Mohamad Ikhwan Sani, Andrea Balla, Rosa Scaramuzzo, Pasquale Lepiane, Andrea Bottari, Fabio Staderini, Fabio Cianchi, Andrea Cavallaro, Antonio Zanghi, Alessandro Cappellani, Roberto Campagnacci, Angela Maurizi, Mario Martinotti, Annamaria Ruggieri, Asri Che Jusoh, Karim Abdul Rahman, Anis Suraya M. Zulkifli, Barbara Petronio, Belen Matias-Garcia, Ana Quiroga-Valcarcel, Fernando Mendoza-Moreno, Boyko Atanasov, Fabio Cesare Campanile, Ilaria Vecchioni, Luca Cardinali, Grazia Travaglini, Elisa Sebastiani, Serge Chooklin, Serhii Chuklin, Pasquale Cianci, Enrico Restini, Sabino Capuzzolo, Giuseppe Curro, Rosalinda Filippo, Michele Rispoli, Daniel Aparicio-Sanchez, Virginia Duran Munoz-Cruzado, Sandra Dios Barbeito, Samir Delibegovic, Amar Kesetovic, Diego Sasia, Felice Borghi, Giorgio Giraudo, Diego Visconti, Emanuele Doria, Mauro Santarelli, Davide Luppi, Stefano Bonilauri, Ugo Grossi, Giacomo Zanus, Alberto Sartori, Giacomo Piatto, Maurizio De Luca, Domenico Vita, Luigi Conti, Patrizio Capelli, Gaetano Maria Cattaneo, Athanasios Marinis, Styliani-Aikaterini Vederaki, Mehmet Bayrak, Yasemin Altintas, Mustafa Yener Uzunoglu, Iskender Eren Demirbas, Yuksel Altinel, Serhat Meric, Yunus Emre Aktimur, Derya Salim Uymaz, Nail Omarov, Ibrahim Azamat, Eftychios Lostoridis, Eleni-Aikaterini Nagorni, Antonio Pujante, Gabriele Anania, Cristina Bombardini, Francesco Bagolini, Emre Gonullu, Baris Mantoglu, Recayi Capoglu, Stefano Cappato, Elena Muzio, Elif Colak, Suleyman Polat, Zehra Alan Koylu, Fatih Altintoprak, Zulfu Bayhan, Emrah Akin, Enrico Andolfi, Sulce Rezart, Jae Il Kim, Sung Won Jung, Yong Chan Shin, Octavian Enciu, Elena Adelina Toma, Fabio Medas, Gian Luigi Canu, Federico Cappellacci, Fabrizio d'Acapito, Giorgio Ercolani, Leonardo Solaini, Francesco Roscio, Federico Clerici, Roberta Gelmini, Francesco Serra, Elena Giulia Rossi, Francesco Fleres, Guglielmo Clarizia, Alessandro Spolini, Francesco Ferrara, Gabriela Nita, Jlenia Sarnari, Mahir Gachabayov, Abakar Abdullaev, Gaetano Poillucci, Gian Marco Palini, Simone Veneroni, Gianluca Garulli, Micaela Piccoli, Gianmaria Casoni Pattacini, Francesca Pecchini, Giulio Argenio, Mariano Fortunato Armellino, Giuseppe Brisinda, Silvia Tedesco, Pietro Fransvea, Giuseppe Ietto, Caterina Franchi, Giulio Carcano, Gennaro Martines, Giuseppe Trigiante, Giulia Negro, Gustavo Machain Vega, Agustin Rodriguez Gonzalez, Leonardo Ojeda, Gaetano Piccolo, Andrea Bondurri, Anna Maffioli, Claudio Guerci, Boo Han Sin, Zamri Zuhdi, Azlanudin Azman, Hussam Mousa, Shadi Al Bahri, Goran Augustin, Ivan Romic, Trpimir Moric, Ioannis Nikolopoulos, Jacopo Andreuccetti, Giusto Pignata, Rossella D'Alessio, Jakub Kenig, Urszula Skorus, Gustavo Pereira Fraga, Elcio Shiyoiti Hirano, Jackson Vinicius de Lima Bertuol, Arda Isik, Eray Kurnaz, Mohammad Sohail Asghar, Ameer Afzal, Ali Akbar, Taxiarchis Konstantinos Nikolouzakis, Konstantinos Lasithiotakis, Emmanuel Chrysos, Koray Das, Nazmi Ozer, Ahmet Seker, Mohamed Ibrahim, Hytham K. S. Hamid, Ahmed Babiker, Konstantinos Bouliaris, George Koukoulis, Chrysoula-Christina Kolla, Andrea Lucchi, Laura Agostinelli, Antonio Taddei, Laura Fortuna, Carlotta Agostini, Leo Licari, Simona Viola, Cosimo Callari, Letizia Laface, Emmanuele Abate, Massimiliano Casati, Alessandro Anastasi, Giuseppe Canonico, Linda Gabellini, Lorenzo Tosi, Anna Guariniello, Federico Zanzi, Lovenish Bains, Larysa Sydorchuk, Oksana Iftoda, Andrii Sydorchuk, Michele Malerba, Federico Costanzo, Raffaele Galleano, Michela Monteleone, Andrea Costanzi, Carlo Riva, Maciej Waledziak, Andrzej Kwiatkowski, Lukasz Czyzykowski, Piotr Major, Marcin Strzalka, Maciej Matyja, Michal Natkaniec, Maria Rosaria Valenti, Maria Domenica Pia Di Vita, Maria Sotiropoulou, Stylianos Kapiris, Damien Massalou, Massimiliano Veroux, Alessio Volpicelli, Rossella Gioco, Matteo Uccelli, Marta Bonaldi, Stefano Olmi, Matteo Nardi, Giada Livadoti, Cristian Mesina, Theodor Viorel Dumitrescu, Mihai Calin Ciorbagiu, Michele Ammendola, Giorgio Ammerata, Roberto Romano, Mihail Slavchev, Evangelos P. Misiakos, Emmanouil Pikoulis, Dimitrios Papaconstantinou, Mohamed Elbahnasawy, Sherief Abdel-Elsalam, Daniel M. Felsenreich, Julia Jedamzik, Nikolaos Michalopoulos, Theodoros A. Sidiropoulos, Maria Papadoliopoulou, Nicola Cillara, Antonello Deserra, Alessandro Cannavera, Ionut Negoi, Dimitrios Schizas, Athanasios Syllaios, Ilias Vagios, Stavros Gourgiotis, Nick Dai, Rekha Gurung, Marcus Norrey, Antonio Pesce, Carlo Vittorio Feo, Nicolo Fabbri, Nikolaos Machairas, Panagiotis Dorovinis, Myrto D. Keramida, Francesk Mulita, Georgios Ioannis Verras, Michail Vailas, Omer Yalkin, Nidal Iflazoglu, Direnc Yigit, Oussama Baraket, Karim Ayed, Mohamed Hedi Ghalloussi, Parmenion Patias, Georgios Ntokos, Razrim Rahim, Miklosh Bala, Asaf Kedar, Robert G. Sawyer, Anna Trinh, Kelsey Miller, Ruslan Sydorchuk, Ruslan Knut, Oleksandr Plehutsa, Rumeysa Kevser Liman, Zeynep Ozkan, Saleh Abdel Kader, Sanjay Gupta, Monika Gureh, Sara Saeidi, Mohsen Aliakbarian, Amin Dalili, Tomohisa Shoko, Mitsuaki Kojima, Raira Nakamoto, Semra Demirli Atici, Gizem Kilinc Tuncer, Tayfun Kaya, Spiros G. Delis, Stefano Rossi, Biagio Picardi, Simone Rossi Del Monte, Tania Triantafyllou, Dimitrios Theodorou, Tadeja Pintar, Jure Salobir, Dimitrios K. Manatakis, Nikolaos Tasis, Vasileios Acheimastos, Orestis Ioannidis, Lydia Loutzidou, Savvas Symeonidis, Tiago Correia de Sa, Monica Rocha, Tommaso Guagni, Desire Pantalone, Gherardo Maltinti, Vladimir Khokha, Wafaa Abdel-Elsalam, Basma Ghoneim, Jose Antonio Lopez-Ruiz, Yasin Kara, Syaza Zainudin, Firdaus Hayati, Nornazirah Azizan, Victoria Tan Phooi Khei, Rebecca Choy Xin Yi, Harivinthan Sellappan, Zaza Demetrashvili, Nika Lekiashvili, Ana Tvaladze, Caterina Froiio, Daniele Bernardi, Luigi Bonavina, Angeles Gil-Olarte, Sebastiano Grassia, Estela Romero-Vargas, Francesco Bianco, Andrew A. Gumbs, Agron Dogjani, Ferdinando Agresta, Andrey Litvin, Zsolt J. Balogh, George Gendrikson, Costanza Martino, Dimitrios Damaskos, Nikolaos Pararas, Andrew Kirkpatrick, Mikhail Kurtenkov, Felipe Couto Gomes, Adolfo Pisanu, Oreste Nardello, Fabrizio Gambarini, Hager Aref, Nicola de'Angelis, Vanni Agnoletti, Antonio Biondi, Marco Vacante, Giulia Griggio, Roberta Tutino, Marco Massani, Giovanni Bisetto, Savino Occhionorelli, Dario Andreotti, Domenico Lacavalla, Walter L. Biffl, Fausto Catena

Summary: The incidence of gangrenous cholecystitis is higher in COVID patients compared with non-COVID patients with acute cholecystitis. Gangrenous cholecystitis in COVID patients is associated with high-grade Clavien-Dindo postoperative complications, longer hospital stay, and higher mortality rate. COVID-19 infection and gangrenous cholecystitis are not absolute contraindications for laparoscopic cholecystectomy and should be evaluated on a case-by-case basis by experts.

WORLD JOURNAL OF EMERGENCY SURGERY (2022)

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Article Emergency Medicine

Surgeons' perspectives on artificial intelligence to support clinical decision-making in trauma and emergency contexts: results from an international survey

Lorenzo Cobianchi, Daniele Piccolo, Francesca Dal Mas, Vanni Agnoletti, Luca Ansaloni, Jeremy Balch, Walter Biff, Giovanni Butturini, Fausto Catena, Federico Coccolini, Stefano Denicolai, Belinda De Simone, Isabella Frigerio, Paola Fugazzola, Gianluigi Marseglia, Giuseppe Roberto Marseglia, Jacopo Martellucci, Mirko Modenese, Pietro Previtali, Federico Ruta, Alessandro Venturi, Haytham M. Kaafarani, Tyler J. Loftus

Summary: This study investigates trauma and emergency surgeons' knowledge and perception of using AI-based tools in clinical decision-making processes. The results show that there are technology enthusiasts and skeptics among surgeons, with a preference towards more classical decision-making aids. Lack of knowledge about AI and mistrust are also observed.

WORLD JOURNAL OF EMERGENCY SURGERY (2023)

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Article Emergency Medicine

Time for a paradigm shift in shared decision-making in trauma and emergency surgery? Results from an international survey

Lorenzo Cobianchi, Francesca Dal Mas, Vanni Agnoletti, Luca Ansaloni, Walter Biffl, Giovanni Butturini, Stefano Campostrini, Fausto Catena, Stefano Denicolai, Paola Fugazzola, Jacopo Martellucci, Maurizio Massaro, Pietro Previtali, Federico Ruta, Alessandro Venturi, Sarah Woltz, Haytham M. Kaafarani, Tyler J. Loftus, Team Dynamics Study Grp

Summary: This study explores the understanding, barriers, and facilitators of shared decision-making (SDM) in trauma and emergency surgery. Findings show that less than half of the surgeons understand SDM and 30% still see value in exclusively engaging multidisciplinary provider teams without involving the patient. The inclusion of SDM practices in clinical guidelines is recommended.

WORLD JOURNAL OF EMERGENCY SURGERY (2023)

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Article Surgery

Should multifocality be an indication for prophylactic central neck dissection in papillary thyroid cancer?

Kayhan Ozdemir, Ahmet Tarik Harmantepe, Emre Gonullu, Belma Kocer, Zulfu Bayhan

Summary: Although multifocality is common in papillary thyroid cancer, its impact on lymphatic metastasis and the necessity of central dissection are still debated. In our study of 258 patients who underwent thyroidectomy, lymph node metastasis was not significantly increased in the presence of multifocality. However, bilateral multifocal tumors exhibited more aggressive features and a higher risk for central lymph node metastasis. Prophylactic central lymph node dissection could be considered in patients with multifocal tumors and no preoperative or intraoperative lymph node metastasis.

UPDATES IN SURGERY (2023)

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Article Medicine, General & Internal

COVID-19 and related gastrointestinal symptoms: An observational study

Ali Cihat Yildirim, Sevil Alkan Ceviker, Sezgin Zeren, Mehmet Fatih Eckici, Faik Yaylak, Mustafa Cem Algin, Ozlem Arik

Summary: Gastrointestinal symptoms are common in COVID-19 patients, with nonspecific abdominal pain and diarrhea being the main manifestations. These symptoms do not seem to have a detrimental effect on the progression of the disease, and surgical intervention is not necessary.

MARMARA MEDICAL JOURNAL (2022)

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