Circadian Redox and Metabolic Oscillations in Mammalian Systems

Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes

(2016) Elizabeth A. Yu et al.   Aging-US

The Role of Redox Signaling in Epigenetics and Cardiovascular Disease

(2013) Gene H. Kim et al.   ANTIOXIDANTS & REDOX SIGNALING

Blood-Borne Circadian Signal Stimulates Daily Oscillations in Actin Dynamics and SRF Activity

(2013) Alan Gerber et al.   CELL

Bmal1 and  -Cell Clock Are Required for Adaptation to Circadian Disruption, and Their Loss of Function Leads to Oxidative Stress-Induced  -Cell Failure in Mice

(2013) J. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone methyltransferase MLL3 contributes to genome-scale circadian transcription

(2013) Utham K. Valekunja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian acetylome reveals regulation of mitochondrial metabolic pathways

(2013) Selma Masri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust Circadian Oscillations in Growing Cyanobacteria Require Transcriptional Feedback

(2013) S.-W. Teng et al.   SCIENCE

The Circadian Clock Coordinates Ribosome Biogenesis

(2013) Céline Jouffe et al.   PLOS BIOLOGY

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

In Vivo Monitoring of Peripheral Circadian Clocks in the Mouse

(2012) Yu Tahara et al.   CURRENT BIOLOGY

Biomarkers of Protein Oxidation in Human Disease

(2012) A. Garcia-Garcia et al.   CURRENT MOLECULAR MEDICINE

Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators

(2012) C. Saini et al.   GENES & DEVELOPMENT

Circadian control of mRNA polyadenylation dynamics regulates rhythmic protein expression

(2012) S. Kojima et al.   GENES & DEVELOPMENT

Feedback Control of Adrenal Steroidogenesis via H2O2-Dependent, Reversible Inactivation of Peroxiredoxin III in Mitochondria

(2012) In Sup Kil et al.   MOLECULAR CELL

Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β

(2012) Han Cho et al.   NATURE

Circadian topology of metabolism

(2012) Joseph Bass   NATURE

Peroxiredoxins are conserved markers of circadian rhythms

(2012) Rachel S. Edgar et al.   NATURE

Persistent Cell-Autonomous Circadian Oscillations in Fibroblasts Revealed by Six-Week Single-Cell Imaging of PER2::LUC Bioluminescence

(2012) Tanya L. Leise et al.   PLoS One

Toward the Beginning of Time: Circadian Rhythms in Metabolism Precede Rhythms in Clock Gene Expression in Mouse Embryonic Stem Cells

(2012) Jiffin K. Paulose et al.   PLoS One

Coordination of the transcriptome and metabolome by the circadian clock

(2012) K. L. Eckel-Mahan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human blood metabolite timetable indicates internal body time

(2012) T. Kasukawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human circadian metabolome

(2012) R. Dallmann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Rhythm of Redox State Regulates Excitability in Suprachiasmatic Nucleus Neurons

(2012) T. A. Wang et al.   SCIENCE

Transcriptional Architecture and Chromatin Landscape of the Core Circadian Clock in Mammals

(2012) N. Koike et al.   SCIENCE

Rhythmic Nucleotide Synthesis in the Liver: Temporal Segregation of Metabolites

(2012) Jean-Michel Fustin et al.   Cell Reports

Genome-Wide RNA Polymerase II Profiles and RNA Accumulation Reveal Kinetics of Transcription and Associated Epigenetic Changes During Diurnal Cycles

(2012) Gwendal Le Martelot et al.   PLOS BIOLOGY

Nascent-Seq reveals novel features of mouse circadian transcriptional regulation

(2012) Jerome S Menet et al.   eLife

Peroxides and Peroxidases in the Endoplasmic Reticulum: Integrating Redox Homeostasis and Oxidative Folding

(2011) Taichi Kakihana et al.   ANTIOXIDANTS & REDOX SIGNALING

Global Proteomic Assessment of the Classical Protein-Tyrosine Phosphatome and “Redoxome”

(2011) Robert Karisch et al.   CELL

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

Temporal orchestration of circadian autophagy rhythm by C/EBPβ

(2011) Di Ma et al.   EMBO JOURNAL

Circadian rhythms in the hypothalamo–pituitary–adrenal (HPA) axis

(2011) A. Kalsbeek et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Regulation of reactive oxygen species generation in cell signaling

(2011) Yun Soo Bae et al.   MOLECULES AND CELLS

On time metabolism

(2011) Joseph Bass   NATURE

Cryptochromes mediate rhythmic repression of the glucocorticoid receptor

(2011) Katja A. Lamia et al.   NATURE

Circadian rhythms persist without transcription in a eukaryote

(2011) John S. O’Neill et al.   NATURE

Circadian clocks in human red blood cells

(2011) John S. O’Neill et al.   NATURE

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

Understanding systems-level properties: timely stories from the study of clocks

(2011) John B. Hogenesch et al.   NATURE REVIEWS GENETICS

Linking neural activity and molecular oscillations in the SCN

(2011) Christopher S. Colwell   NATURE REVIEWS NEUROSCIENCE

Neurobiology of food anticipatory circadian rhythms

(2011) Ralph E. Mistlberger   PHYSIOLOGY & BEHAVIOR

Protein Phosphatase 1 (PP1) Is a Post-Translational Regulator of the Mammalian Circadian Clock

(2011) Isabelle Schmutz et al.   PLoS One

Cell-autonomous circadian clock of hepatocytes drives rhythms in transcription and polyamine synthesis

(2011) A. Atwood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The nuclear receptor REV-ERB  mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines

(2011) J. E. Gibbs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circadian Control of Global Gene Expression Patterns

(2010) Colleen J. Doherty et al.   Annual Review of Genetics

Systems Biology of Mammalian Circadian Clocks

(2010) Hideki Ukai et al.   Annual Review of Physiology

Suprachiasmatic Nucleus: Cell Autonomy and Network Properties

(2010) David K. Welsh et al.   Annual Review of Physiology

Multiple Functions of Peroxiredoxins: Peroxidases, Sensors and Regulators of the Intracellular Messenger H2O2, and Protein Chaperones

(2010) Sue Goo Rhee et al.   ANTIOXIDANTS & REDOX SIGNALING

Signaling Functions of Reactive Oxygen Species

(2010) Henry Jay Forman et al.   BIOCHEMISTRY

SnapShot: Reactive Oxygen Intermediates (ROI)

(2010) Carl Nathan et al.   CELL

Circadian clocks and cell division

(2010) Carl Hirschie Johnson   CELL CYCLE

Circadian Clock-Coordinated 12 Hr Period Rhythmic Activation of the IRE1α Pathway Controls Lipid Metabolism in Mouse Liver

(2010) Gaspard Cretenet et al.   Cell Metabolism

Thiol-disulfide Redox Dependence of Heme Binding and Heme Ligand Switching in Nuclear Hormone Receptor Rev-erbβ

(2010) Nirupama Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes

(2010) Biliana Marcheva et al.   NATURE

Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis

(2010) Eric E Zhang et al.   NATURE MEDICINE

The histone methyltransferase MLL1 permits the oscillation of circadian gene expression

(2010) Sayako Katada et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Robust circadian clocks from coupled protein-modification and transcription-translation cycles

(2010) D. Zwicker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative Protein Folding in the Secretory Pathway and Redox Signaling Across Compartments and Cells

(2010) Éva Margittai et al.   TRAFFIC

Regulatory crosstalk of the metabolic network

(2010) Nana-Maria Grüning et al.   TRENDS IN BIOCHEMICAL SCIENCES

Coupling of a Core Post-Translational Pacemaker to a Slave Transcription/Translation Feedback Loop in a Circadian System

(2010) Ximing Qin et al.   PLOS BIOLOGY

Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases

(2009) Douglas B Kell   BMC Medical Genomics

A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells

(2009) Eric E. Zhang et al.   CELL

Proteomic Analysis Reveals the Role of Synaptic Vesicle Cycling in Sustaining the Suprachiasmatic Circadian Clock

(2009) Michael J. Deery et al.   CURRENT BIOLOGY

Cytochrome P450 and the Biological Clock in Mammals

(2009) Oren Froy   CURRENT DRUG METABOLISM

Lesion studies targeting food-anticipatory activity

(2009) Alec J. Davidson   EUROPEAN JOURNAL OF NEUROSCIENCE

Typical 2-Cys peroxiredoxins - structures, mechanisms and functions

(2009) Andrea Hall et al.   FEBS Journal

A large-scale functional RNAi screen reveals a role for CK2 in the mammalian circadian clock

(2009) B. Maier et al.   GENES & DEVELOPMENT

Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity

(2009) Tobias B Dansen et al.   Nature Chemical Biology

Measurement of internal body time by blood metabolomics

(2009) Y. Minami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Daily rhythms of food-anticipatory behavioral activity do not require the known circadian clock

(2009) K.-F. Storch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

(2009) Christopher Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CKI / -dependent phosphorylation is a temperature-insensitive, period-determining process in the mammalian circadian clock

(2009) Y. Isojima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AMPK Regulates the Circadian Clock by Cryptochrome Phosphorylation and Degradation

(2009) K. A. Lamia et al.   SCIENCE

Circadian Clock Feedback Cycle Through NAMPT-Mediated NAD+ Biosynthesis

(2009) K. M. Ramsey et al.   SCIENCE

Protein S-glutathionylation: a regulatory device from bacteria to humans

(2009) Isabella Dalle-Donne et al.   TRENDS IN BIOCHEMICAL SCIENCES

Healthy clocks, healthy body, healthy mind

(2009) Akhilesh B. Reddy et al.   TRENDS IN CELL BIOLOGY

CBP/p300 is a cell type-specific modulator of CLOCK/BMAL1-mediated transcription

(2009) Hiroshi Hosoda et al.   Molecular Brain

The NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control

(2008) Yasukazu Nakahata et al.   CELL

SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation

(2008) Gad Asher et al.   CELL

Cellular Circadian Pacemaking and the Role of Cytosolic Rhythms

(2008) Michael H. Hastings et al.   CURRENT BIOLOGY

Circadian gene expression is resilient to large fluctuations in overall transcription rates

(2008) Charna Dibner et al.   EMBO JOURNAL

Analysis and synthesis of high-amplitude Cis-elements in the mammalian circadian clock

(2008) Y. Kumaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Physiological significance of a peripheral tissue circadian clock

(2008) K. A. Lamia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA