Iron Homeostasis in Peripheral Nervous System, Still a Black Box?

Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis

(2017) Sandro Altamura et al.   JOURNAL OF ALZHEIMERS DISEASE

DMT1 as a candidate for non-transferrin-bound iron uptake in the peripheral nervous system

(2013) Rocio Martínez Vivot et al.   BIOFACTORS

Regulation of systemic iron homeostasis

(2013) Karin E. Finberg   CURRENT OPINION IN HEMATOLOGY

Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atypical restless leg syndrome

(2013) Anna Cozzi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inflammation alters the expression of DMT1, FPN1 and hepcidin, and it causes iron accumulation in central nervous system cells

(2013) Pamela Urrutia et al.   JOURNAL OF NEUROCHEMISTRY

Lower molecular weight intravenous iron dextran for restless legs syndrome

(2013) Yong Won Cho et al.   SLEEP MEDICINE

Relation of Cytosolic Iron Excess to Cardiomyopathy of Friedreich's Ataxia

(2012) R. Liane Ramirez et al.   AMERICAN JOURNAL OF CARDIOLOGY

Hepcidin and iron homeostasis

(2012) Tomas Ganz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ferroportin-mediated iron transport: Expression and regulation

(2012) Diane M. Ward et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The role of mitochondria in cellular iron–sulfur protein biogenesis and iron metabolism

(2012) Roland Lill et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Isoform specific regulation of divalent metal (ion) transporter (DMT1) by proteasomal degradation

(2012) Michael D. Garrick et al.   BIOMETALS

Iron toxicity in neurodegeneration

(2012) Marco T. Núñez et al.   BIOMETALS

Extrinsic cellular and molecular mediators of peripheral axonal regeneration

(2012) Frank Bosse   CELL AND TISSUE RESEARCH

Diabetic neuropathy

(2012) Brian C. Callaghan et al.   CURRENT OPINION IN NEUROLOGY

Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated with Friedreich's ataxia

(2012) A. Martelli et al.   Disease Models & Mechanisms

ZIP8 Is an Iron and Zinc Transporter Whose Cell-surface Expression Is Up-regulated by Cellular Iron Loading

(2012) Chia-Yu Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Charcot-Marie-Tooth disease-linked protein SIMPLE functions with the ESCRT machinery in endosomal trafficking

(2012) Samuel M. Lee et al.   JOURNAL OF CELL BIOLOGY

Biology of the blood–nerve barrier and its alteration in immune mediated neuropathies

(2012) Takashi Kanda   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Mitochondria and Peripheral Neuropathies

(2012) Anne Vital et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Iron Efflux from Astrocytes Plays a Role in Remyelination

(2012) K. Schulz et al.   JOURNAL OF NEUROSCIENCE

Diabetic neuropathy: clinical manifestations and current treatments

(2012) Brian C Callaghan et al.   LANCET NEUROLOGY

Iron and holotransferrin induce cAMP-dependent differentiation of Schwann cells

(2012) C. Salis et al.   NEUROCHEMISTRY INTERNATIONAL

A French family with Charcot–Marie–Tooth disease related to simultaneous heterozygous MFN2 and GDAP1 mutations

(2012) Anne Vital et al.   NEUROMUSCULAR DISORDERS

c-Jun Reprograms Schwann Cells of Injured Nerves to Generate a Repair Cell Essential for Regeneration

(2012) Peter J. Arthur-Farraj et al.   NEURON

Free radicals and antioxidants: updating a personal view

(2012) Barry Halliwell   NUTRITION REVIEWS

Myelin Regeneration: A Recapitulation of Development?

(2011) Stephen P.J. Fancy et al.   Annual Review of Neuroscience

Functional roles of transferrin in the brain

(2011) Dominique F. Leitner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Glutathione: a key component of the cytoplasmic labile iron pool

(2011) Robert C. Hider et al.   BIOMETALS

Friedreich's ataxia: the vicious circle hypothesis revisited

(2011) Aurélien Bayot et al.   BMC Medicine

The identification of gene expression profiles associated with progression of human diabetic neuropathy

(2011) Junguk Hur et al.   BRAIN

Profile of altered brain iron acquisition in restless legs syndrome

(2011) J. R. Connor et al.   BRAIN

Genetics of Neurodegeneration with Brain Iron Accumulation

(2011) Allison Gregory et al.   Current Neurology and Neuroscience Reports

Hyperinsulinemia Induces Insulin Resistance in Dorsal Root Ganglion Neurons

(2011) Bhumsoo Kim et al.   ENDOCRINOLOGY

Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential

(2011) Rebecca Noack et al.   HUMAN MOLECULAR GENETICS

Functional Recovery after Peripheral Nerve Injury is Dependent on the Pro-Inflammatory Cytokines IL-1  and TNF: Implications for Neuropathic Pain

(2011) S. Nadeau et al.   JOURNAL OF NEUROSCIENCE

Ascorbic acid in Charcot–Marie–Tooth disease type 1A (CMT-TRIAAL and CMT-TRAUK): a double-blind randomised trial

(2011) Davide Pareyson et al.   LANCET NEUROLOGY

Diabetic neuropathy: cellular mechanisms as therapeutic targets

(2011) Andrea M. Vincent et al.   Nature Reviews Neurology

Simultaneous MFN2 and GDAP1 mutations cause major mitochondrial defects in a patient with CMT

(2011) J. Cassereau et al.   NEUROLOGY

Ferritin as an important player in neurodegeneration

(2011) Andrzej Friedman et al.   PARKINSONISM & RELATED DISORDERS

Regulation of brain iron and copper homeostasis by brain barrier systems: Implication in neurodegenerative diseases

(2011) Wei Zheng et al.   PHARMACOLOGY & THERAPEUTICS

Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice

(2011) Suh Young Jeong et al.   PLoS One

Molecular Mechanisms Regulating Hepcidin Revealed by Hepcidin Disorders

(2011) Clara Camaschella et al.   TheScientificWorldJOURNAL

Pathology and pathogenesis of sensory neuropathy in Friedreich’s ataxia

(2010) Jennifer A. Morral et al.   ACTA NEUROPATHOLOGICA

Homeostatic regulation of the endoneurial microenvironment during development, aging and in response to trauma, disease and toxic insult

(2010) Andrew P. Mizisin et al.   ACTA NEUROPATHOLOGICA

Wallerian Degeneration, WldS, and Nmnat

(2010) Michael P. Coleman et al.   Annual Review of Neuroscience

Cytosolic and mitochondrial ferritins in the regulation of cellular iron homeostasis and oxidative damage

(2010) Paolo Arosio et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Hyperglycemia magnifies Schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity

(2010) Amelia Padilla et al.   BRAIN RESEARCH

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Inherited disorders of iron metabolism

(2010) Clara Camaschella et al.   CURRENT OPINION IN PEDIATRICS

Brain iron metabolism and its perturbation in neurological diseases

(2010) Robert R. Crichton et al.   JOURNAL OF NEURAL TRANSMISSION

Synergistic accumulation of iron and zinc by cultured astrocytes

(2010) Glenda M. Bishop et al.   JOURNAL OF NEURAL TRANSMISSION

Restless legs syndrome: pathophysiology, clinical presentation and management

(2010) Claudia Trenkwalder et al.   Nature Reviews Neurology

Signals to promote myelin formation and repair

(2010) Carla Taveggia et al.   Nature Reviews Neurology

Genome-wide microarray analysis of brain gene expression in mice on a short-term high iron diet

(2010) Daniel Johnstone et al.   NEUROCHEMISTRY INTERNATIONAL

Iron in the Brain

(2010) John L. Beard et al.   NUTRITION REVIEWS

Regulation of Oligodendrocyte Differentiation and Myelination

(2010) B. Emery   SCIENCE

The dorsal root ganglion in Friedreich’s ataxia

(2009) Arnulf H. Koeppen et al.   ACTA NEUROPATHOLOGICA

Heme Scavenging and the Other Facets of Hemopexin

(2009) Emanuela Tolosano et al.   ANTIOXIDANTS & REDOX SIGNALING

Frataxin deficiency induces Schwann cell inflammation and death

(2009) Chunye Lu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders

(2009) Eric Mills et al.   Future Medicinal Chemistry

Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene

(2009) Ana G. Barbeito et al.   JOURNAL OF NEUROCHEMISTRY

Diagnosis, natural history, and management of Charcot–Marie–Tooth disease

(2009) Davide Pareyson et al.   LANCET NEUROLOGY

A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndrome

(2009) Ludger Grote et al.   MOVEMENT DISORDERS

Oxidative stress and cell death in cells expressing L-ferritin variants causing neuroferritinopathy

(2009) Anna Cozzi et al.   NEUROBIOLOGY OF DISEASE

Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant

(2009) M. L.-H. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transferrin-Directed Internalization and Cycling of Transferrin Receptor 2

(2009) Juxing Chen et al.   TRAFFIC

Axon-Glial Signaling and the Glial Support of Axon Function

(2008) Klaus-Armin Nave et al.   Annual Review of Neuroscience

Friedreich Ataxia

(2008) Massimo Pandolfo   ARCHIVES OF NEUROLOGY

The role of iron in type 2 diabetes in humans

(2008) Swapnil N. Rajpathak et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Role of Advanced Glycation End Products in Diabetic Neuropathy

(2008) Kazuhiro Sugimoto et al.   CURRENT PHARMACEUTICAL DESIGN

Molecular mechanisms of inherited demyelinating neuropathies

(2008) Steven S. Scherer et al.   GLIA

Neuregulin-1, a key axonal signal that drives Schwann cell growth and differentiation

(2008) Carmen Birchmeier et al.   GLIA

Development of the Schwann cell lineage: From the neural crest to the myelinated nerve

(2008) Ashwin Woodhoo et al.   GLIA

Oligodendrocytes and myelination: The role of iron

(2008) Bozho Todorich et al.   GLIA

Tim-2 is the receptor for H-ferritin on oligodendrocytes

(2008) Bozho Todorich et al.   JOURNAL OF NEUROCHEMISTRY

Is there a higher risk of restless legs syndrome in peripheral neuropathy?

(2008) E. Hattan et al.   NEUROLOGY