The Stress Protein/Chaperone Grp94 Counteracts Muscle Disuse Atrophy by Stabilizing Subsarcolemmal Neuronal Nitric Oxide Synthase

Deletion of muscle GRP94 impairs both muscle and body growth by inhibiting local IGF production

(2012) Elisabeth R. Barton et al.   FASEB JOURNAL

Variable phenotype of del45-55 Becker patients correlated with nNOSµ mislocalization and RYR1 hypernitrosylation

(2012) Christel Gentil et al.   HUMAN MOLECULAR GENETICS

The Molecular Chaperone gp96/GRP94 Interacts with Toll-like Receptors and Integrins via Its C-terminal Hydrophobic Domain

(2012) Shuang Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sparing of muscle mass and function by passive loading in an experimental intensive care unit model

(2012) Guillaume Renaud et al.   JOURNAL OF PHYSIOLOGY-LONDON

Passive stretch reduces calpain activity through nitric oxide pathway in unloaded soleus muscles

(2012) Peng-Tao Xu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mechanistic Links Between Oxidative Stress and Disuse Muscle Atrophy

(2011) Scott K. Powers et al.   ANTIOXIDANTS & REDOX SIGNALING

(-)-Epigallocatechin gallate attenuates NADPH-d/nNOS expression in motor neurons of rats following peripheral nerve injury

(2011) I-Hua Wei et al.   BMC NEUROSCIENCE

Mitochondrial-targeted antioxidants protect skeletal muscle against immobilization-induced muscle atrophy

(2011) Kisuk Min et al.   JOURNAL OF APPLIED PHYSIOLOGY

Loss of sarcolemmal nNOS is common in acquired and inherited neuromuscular disorders

(2011) E. L. Finanger Hedderick et al.   NEUROLOGY

Oxidative stress and muscle homeostasis

(2010) Antonio Musarò et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Golgi and sarcolemmal neuronal NOS differentially regulate contraction-induced fatigue and vasoconstriction in exercising mouse skeletal muscle

(2010) Justin M. Percival et al.   JOURNAL OF CLINICAL INVESTIGATION

Nitrosative stress elicited by nNOSµ delocalization inhibits muscle force in dystrophin-null mice

(2010) Dejia Li et al.   JOURNAL OF PATHOLOGY

Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation

(2010) Maurizio Vitadello et al.   ARTHRITIS RESEARCH & THERAPY

Induction of heat shock proteins for protection against oxidative stress

(2009) Bernadett Kalmar et al.   ADVANCED DRUG DELIVERY REVIEWS

Glucose regulated protein 94 is required for muscle differentiation through its control of the autocrine production of insulin-like growth factors

(2009) Olga Ostrovsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Apocynin attenuates diaphragm oxidative stress and protease activation during prolonged mechanical ventilation

(2009) Joseph M. McClung et al.   CRITICAL CARE MEDICINE

Hsp27 inhibits IKKβ-induced NF-κB activity and skeletal muscle atrophy

(2009) Stephen L. Dodd et al.   FASEB JOURNAL

A transient antioxidant stress response accompanies the onset of disuse atrophy in human skeletal muscle

(2009) Luciano Dalla Libera et al.   JOURNAL OF APPLIED PHYSIOLOGY

Grp94 acts as a mediator of curcumin-induced antioxidant defence in myogenic cells

(2009) Paola Pizzo et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hypernitrosylated ryanodine receptor calcium release channels are leaky in dystrophic muscle

(2009) Andrew M Bellinger et al.   NATURE MEDICINE

Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications

(2009) Li Zhou et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Altered myoplasmic Ca2+ handling in rat fast-twitch skeletal muscle fibres during disuse atrophy

(2009) Norbert Weiss et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts

(2008) Martina Frasson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Cellular distribution of Hsp70 expression in rat skeletal muscles. Effects of moderate exercise training and chronic hypoxia

(2008) Elena Tarricone et al.   CELL STRESS & CHAPERONES

Increased iron content and RNA oxidative damage in skeletal muscle with aging and disuse atrophy

(2008) Tim Hofer et al.   EXPERIMENTAL GERONTOLOGY

Hsp70 overexpression inhibits NF-κB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy

(2008) Sarah M. Senf et al.   FASEB JOURNAL

Ryanodine receptor type-1 (RyR1) expression and protein S-nitrosylation pattern in human soleus myofibres following bed rest and exercise countermeasure

(2008) Michele Salanova et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Effects of spaceflight on murine skeletal muscle gene expression

(2008) David L. Allen et al.   JOURNAL OF APPLIED PHYSIOLOGY

Xanthine oxidase contributes to mechanical ventilation-induced diaphragmatic oxidative stress and contractile dysfunction

(2008) Melissa A. Whidden et al.   JOURNAL OF APPLIED PHYSIOLOGY