Hydrogen Peroxide Sensing and Signaling by Protein Kinases in the Cardiovascular System

Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension

(2012) Oleksandra Prysyazhna et al.   NATURE MEDICINE

H 2 O 2 -Induced Dilation in Human Coronary Arterioles: Role of Protein Kinase G Dimerization and Large-Conductance Ca 2+ -Activated K + Channel Activation

(2011) David X. Zhang et al.   CIRCULATION RESEARCH

Sustained CaMKII activity mediates transient oxidative stress-induced long-term facilitation of L-type Ca2+ current in cardiomyocytes

(2011) Young-Hwan Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Oxidation of CaMKII determines the cardiotoxic effects of aldosterone

(2011) B Julie He et al.   NATURE MEDICINE

Crystal Structure of cGMP-Dependent Protein Kinase Reveals Novel Site of Interchain Communication

(2011) Brent W. Osborne et al.   STRUCTURE

Glyceraldehyde 3-Phosphate Dehydrogenase is Unlikely to Mediate Hydrogen Peroxide Signaling: Studies with a Novel Anti-Dimedone Sulfenic Acid Antibody

(2010) Claire Maller et al.   ANTIOXIDANTS & REDOX SIGNALING

Redox Regulation of Soluble Epoxide Hydrolase by 15-Deoxy-Δ-Prostaglandin J 2 Controls Coronary Hypoxic Vasodilation

(2010) Rebecca L. Charles et al.   CIRCULATION RESEARCH

Structure of D-AKAP2:PKA RI Complex: Insights into AKAP Specificity and Selectivity

(2010) Ganapathy N. Sarma et al.   STRUCTURE

Angiotensin II–Induced Oxidative Stress Resets the Ca 2+ Dependence of Ca 2+ –Calmodulin Protein Kinase II and Promotes a Death Pathway Conserved Across Different Species

(2009) Julieta Palomeque et al.   CIRCULATION RESEARCH

The Right to Choose: Multiple Pathways for Activating Copper,Zinc Superoxide Dismutase

(2009) Jeffry M. Leitch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transnitrosylating Nitric Oxide Species Directly Activate Type I Protein Kinase A, Providing a Novel Adenylate Cyclase-independent Cross-talk to β-Adrenergic-like Signaling

(2009) Joseph R. Burgoyne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

L-type Ca2+ channel facilitation mediated by H2O2-induced activation of CaMKII in rat ventricular myocytes

(2009) Young-Hwan Song et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Regulation of CaMKII In vivo: The Importance of Targeting and the Intracellular Microenvironment

(2009) Kathryn A. Skelding et al.   NEUROCHEMICAL RESEARCH

Cardiac peroxiredoxins undergo complex modifications during cardiac oxidant stress

(2008) Ewald Schröder et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Sestrin 2 Is Not a Reductase for Cysteine Sulfinic Acid of Peroxiredoxins

(2008) Hyun Ae Woo et al.   ANTIOXIDANTS & REDOX SIGNALING

Hydrogen peroxide as an endogenous mediator and exogenous tool in cardiovascular research: issues and considerations

(2008) E SCHRODER et al.   CURRENT OPINION IN PHARMACOLOGY

Signaling the Signal, Cyclic AMP-dependent Protein Kinase Inhibition by Insulin-formed H2O2and Reactivation by Thioredoxin

(2008) Martha Zentella de Piña et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the sulphiredoxin–peroxiredoxin complex reveals an essential repair embrace

(2008) Thomas J. Jönsson et al.   NATURE

Reconciling the chemistry and biology of reactive oxygen species

(2008) Christine C Winterbourn   Nature Chemical Biology

cGMP-binding Prepares PKG for Substrate Binding by Disclosing the C-terminal Domain

(2007) Vera Alverdi et al.   JOURNAL OF MOLECULAR BIOLOGY