Mitochondrial Protein Synthesis: Efficiency and Accuracy

The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1

(2016) Gino Heeren et al.   Aging-US

Alternative Perspectives on Aging in Caenorhabditis elegans: Reactive Oxygen Species or Hyperfunction?

(2012) David Gems et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of Lifespan by the Mitochondrial Electron Transport Chain: Reactive Oxygen Species-Dependent and Reactive Oxygen Species-Independent Mechanisms

(2012) Filippo Scialo et al.   ANTIOXIDANTS & REDOX SIGNALING

The Cbp3–Cbp6 complex coordinates cytochromebsynthesis withbc1complex assembly in yeast mitochondria

(2012) Steffi Gruschke et al.   JOURNAL OF CELL BIOLOGY

Schizosaccharomyces pombe homologs of the Saccharomyces cerevisiae mitochondrial proteins Cbp6 and Mss51 function at a post-translational step of respiratory complex biogenesis

(2012) Inge Kühl et al.   MITOCHONDRION

Evolutionary and genetic analyses of mitochondrial translation initiation factors identify the missing mitochondrial IF3 in S. cerevisiae

(2012) Gemma C. Atkinson et al.   NUCLEIC ACIDS RESEARCH

The Yeast Retrograde Response as a Model of Intracellular Signaling of Mitochondrial Dysfunction

(2012) S. Michal Jazwinski et al.   Frontiers in Physiology

LRPPRC mutation suppresses cytochrome oxidase activity by altering mitochondrial RNA transcript stability in a mouse model

(2011) Fenghao Xu et al.   BIOCHEMICAL JOURNAL

Human diseases with impaired mitochondrial protein synthesis

(2011) Agnès Rötig   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mechanism of protein biosynthesis in mammalian mitochondria

(2011) Brooke E. Christian et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

(2011) Benedetta Ruzzenente et al.   EMBO JOURNAL

Presequence-dependent folding ensures MrpL32 processing by them-AAA protease in mitochondria

(2011) Florian Bonn et al.   EMBO JOURNAL

Truncation of the Mrp20 protein reveals new ribosome-assembly subcomplex in mitochondria

(2011) Jasvinder Kaur et al.   EMBO REPORTS

Mitochondrial Genomic Dysfunction Causes Dephosphorylation of Sch9 in the Yeast Saccharomyces cerevisiae

(2011) Shigeyuki Kawai et al.   EUKARYOTIC CELL

Termination of Protein Synthesis in Mammalian Mitochondria

(2011) Zofia M. A. Chrzanowska-Lightowlers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cbp3–Cbp6 interacts with the yeast mitochondrial ribosomal tunnel exit and promotes cytochromebsynthesis and assembly

(2011) Steffi Gruschke et al.   JOURNAL OF CELL BIOLOGY

Revisiting the Yeast PPR Proteins—Application of an Iterative Hidden Markov Model Algorithm Reveals New Members of the Rapidly Evolving Family

(2011) Kamil A. Lipinski et al.   MOLECULAR BIOLOGY AND EVOLUTION

Absence of Mitochondrial Translation Control Proteins Extends Life Span by Activating Sirtuin-Dependent Silencing

(2011) Antonio Caballero et al.   MOLECULAR CELL

A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression

(2011) Inge Kühl et al.   NUCLEIC ACIDS RESEARCH

Evolutionary optimization of speed and accuracy of decoding on the ribosome

(2011) I. Wohlgemuth et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Human mitochondrial mRNAs—like members of all families, similar but different

(2010) Richard J. Temperley et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Minor modifications and major adaptations: The evolution of molecular machines driving mitochondrial protein import

(2010) Victoria Hewitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The polypeptide tunnel exit of the mitochondrial ribosome is tailored to meet the specific requirements of the organelle

(2010) Steffi Gruschke et al.   BIOESSAYS

A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome

(2010) Ricarda Richter et al.   EMBO JOURNAL

Preferential Selection of the 5′-Terminal Start Codon on Leaderless mRNAs by Mammalian Mitochondrial Ribosomes

(2010) Brooke E. Christian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteins at the Polypeptide Tunnel Exit of the Yeast Mitochondrial Ribosome

(2010) Steffi Gruschke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRPPRC and SLIRP Interact in a Ribonucleoprotein Complex That Regulates Posttranscriptional Gene Expression in Mitochondria

(2010) Florin Sasarman et al.   MOLECULAR BIOLOGY OF THE CELL

Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation

(2010) David U. Mick et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genome-Wide Screen in Saccharomyces cerevisiae Identifies Vacuolar Protein Sorting, Autophagy, Biosynthetic, and tRNA Methylation Genes Involved in Life Span Regulation

(2010) Paola Fabrizio et al.   PLoS Genetics

Co-translational membrane insertion of mitochondrially encoded proteins

(2009) Martin Ott et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Tor Directly Controls the Atg1 Kinase Complex To Regulate Autophagy

(2009) Y. Kamada et al.   MOLECULAR AND CELLULAR BIOLOGY

Increasing organismal healthspan by enhancing mitochondrial protein quality control

(2009) Karin Luce et al.   NATURE CELL BIOLOGY

Mutation in TACO1, encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome

(2009) Woranontee Weraarpachai et al.   NATURE GENETICS

F1-dependent translation of mitochondrially encoded Atp6p and Atp8p subunits of yeast ATP synthase

(2009) M. Rak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative Stress Induces Parallel Autophagy and Mitochondria Dysfunction in Human Glioma U251 Cells

(2009) Hongyu Zhang et al.   TOXICOLOGICAL SCIENCES

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL

Quality control of mitochondria: protection against neurodegeneration and ageing

(2008) Takashi Tatsuta et al.   EMBO JOURNAL

A Single Mammalian Mitochondrial Translation Initiation Factor Functionally Replaces Two Bacterial Factors

(2008) Rahul Gaur et al.   MOLECULAR CELL

Structural basis for translation termination on the 70S ribosome

(2008) Martin Laurberg et al.   NATURE