CNS Peroxiredoxins and Their Regulation in Health and Disease

The Nrf2-ARE Pathway

(2010) Jeffrey A. Johnson et al.   Annals of the New York Academy of Sciences

Synaptic NMDAR activity suppresses FOXO1 expression via a cis-acting FOXO binding site: FOXO1 is a FOXO target gene

(2010) Bashayer Mubarak et al.   Channels

Changes in the expression of mitochondrial peroxiredoxin and thioredoxin in neurons and glia and their protective effects in experimental cerebral ischemic damage

(2010) In Koo Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Suppression of the Intrinsic Apoptosis Pathway by Synaptic Activity

(2010) F. Leveille et al.   JOURNAL OF NEUROSCIENCE

Excitotoxic Insults Lead to Peroxiredoxin Hyperoxidation

(2010) Frédéric Léveillé et al.   Oxidative Medicine and Cellular Longevity

Cell death: protein misfolding and neurodegenerative diseases

(2009) Tomohiro Nakamura et al.   APOPTOSIS

Peroxiredoxin 5 confers protection against oxidative stress and apoptosis and also promotes longevity inDrosophila

(2009) Svetlana N. Radyuk et al.   BIOCHEMICAL JOURNAL

Coupling of the NMDA receptor to neuroprotective and neurodestructive events

(2009) Giles E. Hardingham   BIOCHEMICAL SOCIETY TRANSACTIONS

Accumulation of overoxidized Peroxiredoxin III in aged rat liver mitochondria

(2009) Clara Musicco et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The complexity of neurobiological processes in acute ischemic stroke

(2009) R. Brouns et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Typical 2-Cys peroxiredoxins - modulation by covalent transformations and noncovalent interactions

(2009) Martin Aran et al.   FEBS Journal

Role of sestrin2 in peroxide signaling in macrophages

(2009) Silke Essler et al.   FEBS LETTERS

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

JNK/FOXO-mediated Neuronal Expression of Fly Homologue of Peroxiredoxin II Reduces Oxidative Stress and Extends Life Span

(2009) Kyu-Sun Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

(2009) Hai Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Synaptic Activity-Mediated Suppression of p53 and Induction of Nuclear Calcium-Regulated Neuroprotective Genes Promote Survival through Inhibition of Mitochondrial Permeability Transition

(2009) D. Lau et al.   JOURNAL OF NEUROSCIENCE

Essential Role of Cytoplasmic cdk5 and Prx2 in Multiple Ischemic Injury Models, In Vivo

(2009) J. Rashidian et al.   JOURNAL OF NEUROSCIENCE

Transcriptional regulation of the AP-1 and Nrf2 target gene sulfiredoxin

(2009) Francesc X. Soriano et al.   MOLECULES AND CELLS

Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage

(2009) Sun-Uk Kim et al.   NEUROBIOLOGY OF AGING

Differential Proteomics Analysis of Specific Carbonylated Proteins in the Temporal Cortex of Aged Rats: The Deterioration of Antioxidant System

(2009) Qingsong Wang et al.   NEUROCHEMICAL RESEARCH

Neuroprotective Effects of the Triterpenoid, CDDO Methyl Amide, a Potent Inducer of Nrf2-Mediated Transcription

(2009) Lichuan Yang et al.   PLoS One

Nuclear Calcium Signaling Controls Expression of a Large Gene Pool: Identification of a Gene Program for Acquired Neuroprotection Induced by Synaptic Activity

(2009) Sheng-Jia Zhang et al.   PLoS Genetics

Glucose and NADPH oxidase drive neuronal superoxide formation in stroke

(2008) Sang Won Suh et al.   ANNALS OF NEUROLOGY

Sestrin 2 Is Not a Reductase for Cysteine Sulfinic Acid of Peroxiredoxins

(2008) Hyun Ae Woo et al.   ANTIOXIDANTS & REDOX SIGNALING

Expression and Changes of Hyperoxidized Peroxiredoxins in Non-Pyramidal and Polymorphic Cells in the Gerbil Hippocampus During Normal Aging

(2008) Ki-Yeon Yoo et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

FoxO transcription factors in the maintenance of cellular homeostasis during aging

(2008) Dervis AM Salih et al.   CURRENT OPINION IN CELL BIOLOGY

Keap1/Nrf2 Signaling Regulates Oxidative Stress Tolerance and Lifespan in Drosophila

(2008) Gerasimos P. Sykiotis et al.   DEVELOPMENTAL CELL

Proteomic identification of nitrated brain proteins in early Alzheimer’s disease inferior parietal lobule

(2008) Tanea T. Reed et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione

(2008) Francesc X. Soriano et al.   JOURNAL OF NEUROCHEMISTRY

Deregulated Cdk5 promotes oxidative stress and mitochondrial dysfunction

(2008) Kai-Hui Sun et al.   JOURNAL OF NEUROCHEMISTRY

Regulation of Neuronal Glutathione Synthesis

(2008) Koji Aoyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

NMDA receptor activity regulates transcription of antioxidant pathways

(2008) Stuart A Lipton   NATURE NEUROSCIENCE

Synaptic NMDA receptor activity boosts intrinsic antioxidant defenses

(2008) Sofia Papadia et al.   NATURE NEUROSCIENCE

In developing hippocampal neurons, NR2B-containing N-methyl-d-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death

(2008) M.-A. Martel et al.   NEUROSCIENCE

Postsynaptic mechanisms of excitotoxicity: Involvement of postsynaptic density proteins, radicals, and oxidant molecules

(2008) J.P. Forder et al.   NEUROSCIENCE

Activation of Nrf2–ARE pathway in brain after traumatic brain injury

(2008) Wei Yan et al.   NEUROSCIENCE LETTERS

Hydroxyoctadecadienoic acid and oxidatively modified peroxiredoxins in the blood of Alzheimer's disease patients and their potential as biomarkers

(2007) Yasukazu Yoshida et al.   NEUROBIOLOGY OF AGING