Coordination of DNA–PK Activation and Nuclease Processing of DNA Termini in NHEJ

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Polymerases in Nonhomologous End Joining: Building a Bridge over Broken Chromosomes

(2010) Dale A. Ramsden   ANTIOXIDANTS & REDOX SIGNALING

Purification and characterization of exonuclease-free Artemis: Implications for DNA-PK-dependent processing of DNA termini in NHEJ-catalyzed DSB repair

(2010) Katherine S. Pawelczak et al.   DNA REPAIR

DNA-PKcs regulates a single-stranded DNA endonuclease activity of Artemis

(2010) Jiafeng Gu et al.   DNA REPAIR

Ku is a 5′-dRP/AP lyase that excises nucleotide damage near broken ends

(2010) Steven A. Roberts et al.   NATURE

Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining

(2009) Brandi L. Mahaney et al.   BIOCHEMICAL JOURNAL

Ku and DNA-dependent Protein Kinase Dynamic Conformations and Assembly Regulate DNA Binding and the Initial Non-homologous End Joining Complex

(2009) Michal Hammel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of a hypomorphic Artemis disease allele on lymphocyte development, DNA end processing, and genome stability

(2009) Ying Huang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Yield, Processing, and Biological Consequences of Clustered DNA Damage Induced by Ionizing Radiation

(2009) Naoya SHIKAZONO et al.   JOURNAL OF RADIATION RESEARCH

Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats

(2009) Bancinyane L. Sibanda et al.   NATURE

Werner Protein Cooperates with the XRCC4-DNA Ligase IV Complex in End-Processing†

(2008) Rika Kusumoto et al.   BIOCHEMISTRY

DNA-PK and ATM phosphorylation sites in XLF/Cernunnos are not required for repair of DNA double strand breaks

(2008) Y YU et al.   DNA REPAIR

A histidine in the β-CASP domain of Artemis is critical for its full in vitro and in vivo functions

(2008) Jean-Pierre de Villartay et al.   DNA REPAIR

Formation of Clustered DNA Damage after High-LET Irradiation: A Review

(2008) Megumi HADA et al.   JOURNAL OF RADIATION RESEARCH

The Ku80 Carboxy Terminus Stimulates Joining and Artemis-Mediated Processing of DNA Ends

(2008) E. Weterings et al.   MOLECULAR AND CELLULAR BIOLOGY

Coordinate 5′ and 3′ endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase

(2008) Steven M. Yannone et al.   NUCLEIC ACIDS RESEARCH

A mechanism for DNA-PK activation requiring unique contributions from each strand of a DNA terminus and implications for microhomology-mediated nonhomologous DNA end joining

(2008) Katherine S. Pawelczak et al.   NUCLEIC ACIDS RESEARCH

Cryo-EM Structure of the DNA-Dependent Protein Kinase Catalytic Subunit at Subnanometer Resolution Reveals α Helices and Insight into DNA Binding

(2008) Dewight R. Williams et al.   STRUCTURE