Living in a Box or Call of the Wild? Revisiting Lifetime Inactivity and Sarcopenia

Diet and exercise signals regulate SIRT3 and activate AMPK and PGC-1α in skeletal muscle

(2016) Orsolya M. Palacios et al.   Aging-US

Multiple Pathways to the Same End: Mechanisms of Myonuclear Apoptosis in Sarcopenia of Aging

(2011) Emanuele Marzetti et al.   TheScientificWorldJOURNAL

The age-related failure of adaptive responses to contractile activity in skeletal muscle is mimicked in young mice by deletion of Cu,Zn superoxide dismutase

(2010) Aphrodite Vasilaki et al.   AGING CELL

Skeletal muscle loss: cachexia, sarcopenia, and inactivity

(2010) William J Evans   AMERICAN JOURNAL OF CLINICAL NUTRITION

Muscle aging and oxidative stress in wild-caught shrews

(2010) Allyson G. Hindle et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY

Cachexia versus sarcopenia

(2010) Yves Rolland et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

PGC-1α is required for training-induced prevention of age-associated decline in mitochondrial enzymes in mouse skeletal muscle

(2010) Lotte Leick et al.   EXPERIMENTAL GERONTOLOGY

Caloric restriction delays aging-induced cellular phenotypes in rhesus monkey skeletal muscle

(2010) Susan H. McKiernan et al.   EXPERIMENTAL GERONTOLOGY

Muscle Wasting in Aged, Sarcopenic Rats Is Associated with Enhanced Activity of the Ubiquitin Proteasome Pathway

(2010) Mikael Altun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Can an NSAID a day keep muscle wasting away?

(2010) Carolyn A. Greig et al.   JOURNAL OF PHYSIOLOGY-LONDON

Heterogeneity in Rate of Decline in Grip, Hip, and Knee Strength and the Risk of All-Cause Mortality: The Women's Health and Aging Study II

(2010) Qian-Li Xue et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Acute exercise reverses aged-induced impairments in insulin signaling in rodent skeletal muscle

(2010) José R. Pauli et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

(2010) Asimina Hiona et al.   PLoS One

Endotoxin Mediated-iNOS Induction Causes Insulin Resistance via ONOO− Induced Tyrosine Nitration of IRS-1 in Skeletal Muscle

(2010) Geneviève Pilon et al.   PLoS One

Physical Inactivity and Obesity Underlie the Insulin Resistance of Aging

(2009) F. Amati et al.   DIABETES CARE

Nuclear Apoptosis Contributes to Sarcopenia

(2009) Stephen E. Alway et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise

(2009) Stephanie Eva Wohlgemuth et al.   EXPERIMENTAL GERONTOLOGY

Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

(2009) Youngmok C. Jang et al.   FASEB JOURNAL

Acetyl-l-carnitine inhibits TNF-α-induced insulin resistance via AMPK pathway in rat skeletal muscle cells

(2009) Zhaofeng Zhang et al.   FEBS LETTERS

Endurance exercise is protective for mice with mitochondrial myopathy

(2009) Tina Wenz et al.   JOURNAL OF APPLIED PHYSIOLOGY

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans

(2009) Ethan J. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Diving into old age: muscular senescence in a large-bodied, long-lived mammal, the Weddell seal (Leptonychotes weddellii)

(2009) A. G. Hindle et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Muscle senescence in short-lived wild mammals, the soricine shrewsBlarina brevicaudaandSorex palustris

(2009) Allyson G. Hindle et al.   Journal of Experimental Zoology Part A-Ecological Genetics and Physiology

Exercise Training Modulates the Nitric Oxide Synthase Profile in Skeletal Muscle From Old Rats

(2009) W. Song et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Exercise alters SIRT1, SIRT6, NAD and NAMPT levels in skeletal muscle of aged rats

(2009) Erika Koltai et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Ros-mediated activation of NF-κB and Foxo during muscle disuse

(2009) Stephen L. Dodd et al.   MUSCLE & NERVE

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of systemic inflammation in age-related muscle weakness and wasting

(2009) H. Degens   SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS

Stem Cell Review Series: Aging of the skeletal muscle stem cell niche

(2008) Suchitra D. Gopinath et al.   AGING CELL

FOXO transcription factors are mechanosensitive and their regulation is altered with aging in the respiratory pump

(2008) Patricia S. Pardo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

TNF induction of atrogin-1/MAFbx mRNA depends on Foxo4 expression but not AKT-Foxo1/3 signaling

(2008) Jennifer S. Moylan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids

(2008) Micah J. Drummond et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Cellular and molecular mechanisms underlying age-related skeletal muscle wasting and weakness

(2008) James G. Ryall et al.   BIOGERONTOLOGY

Lifelong exercise and mild (8%) caloric restriction attenuate age-induced alterations in plantaris muscle morphology, oxidative stress and IGF-1 in the Fischer-344 rat

(2008) Jong-Hee Kim et al.   EXPERIMENTAL GERONTOLOGY

Hsp70 overexpression inhibits NF-κB and Foxo3a transcriptional activities and prevents skeletal muscle atrophy

(2008) Sarah M. Senf et al.   FASEB JOURNAL

Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis

(2008) Micah J. Drummond et al.   JOURNAL OF APPLIED PHYSIOLOGY

TRPC1 binds to caveolin-3 and is regulated by Src kinase - role in Duchenne muscular dystrophy

(2008) O. L. Gervasio et al.   JOURNAL OF CELL SCIENCE

N-Acetylcysteine ameliorates skeletal muscle pathophysiology inmdxmice

(2008) Nicholas P. Whitehead et al.   JOURNAL OF PHYSIOLOGY-LONDON

Effects of Physical Exercise on Myocardial Telomere-Regulating Proteins, Survival Pathways, and Apoptosis

(2008) Christian Werner et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Prolonged treadmill training increases HSP70 in skeletal muscle but does not affect age-related functional deficits

(2007) Anna C. Kayani et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY