Article
Microbiology
Zeliang Liu, Xueqi Jiang, Jie Li, Wenjing Ji, Haijian Zhou, Xinyi Gong, Beibei Miao, Shuang Meng, Like Duan, Qiyuan Shi, Xiao Han, Pengfang Gao, Chienyi Chang, Aiying Dong, Juan Li
Summary: This study analyzed the antibiotic sensitivity and genome sequences of clindamycin-resistant Streptococcus agalactiae strains isolated from clinical samples. The strains showed polymorphisms in molecular types and serotypes, and multiple virulence factor genes were identified in their genomes. This provides basic data for the treatment, prevention, and control of S. agalactiae infections.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Microbiology
Jamisha D. Francis, Miriam A. Guevara, Jacky Lu, Shabir A. Madhi, Gaurav Kwatra, David M. Aronoff, Shannon D. Manning, Jennifer A. Gaddy
Summary: This study found that the susceptibility or resistance to zinc intoxication in Streptococcus agalactiae strains varies based on their isolation source, capsular serotype, and sequence type. Invasive strains are less susceptible to zinc toxicity compared to colonizing strains. Moreover, capsular type III strains and the ST-17 and ST-19 strains exhibit the greatest resilience to zinc stress.
Article
Immunology
Luciana Hernandez, Enriqueta Bottini, Jimena Cadona, Claudio Cacciato, Cristina Monteavaro, Ana Bustamante, Andrea Mariel Sanso
Summary: This study characterized molecular features of S. agalactiae strains causing bovine mastitis in Argentina, revealing serotypes III and II as the most prevalent, virulence genes spb1, hylB, cylE, and PI-2b present in all isolates, and varied frequencies of antibiotic resistance genes.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Microbiology
Elena Carra, Simone Russo, Alessia Micheli, Chiara Garbarino, Matteo Ricchi, Federica Bergamini, Patrizia Bassi, Alice Prosperi, Silvia Piva, Monica Cricca, Roberta Schiavo, Giuseppe Merialdi, Andrea Serraino, Norma Arrigoni
Summary: The zoonotic potential of S. agalactiae was investigated by characterizing isolates from humans and cattle in the Emilia Romagna region of Northern Italy. Common genotypes and antibiotic resistance profiles were found in both species, suggesting interspecies transmission of S. agalactiae between bovines and humans.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Immunology
Hans-Christian Slotved, Kurt Fuursted, Ioanna Drakaki Kavalari, Steen Hoffmann
Summary: Invasive Streptococcus agalactiae (GBS) non-typeable (NT) isolates accounted for 10% of all invasive GBS isolates in Denmark since 1999. A study on 55 clinical NT isolates from 2015 to 2017 revealed that the 35 NT isolates were found in patients above 21 years old with bacteremia, belonging to six different pathogenic clonal complexes. The CDC recommended sequences for capsule genotyping were optimal for serotype prediction, but other capsular sequences should be used for NT isolates if they cannot be genotyped by the CDC method.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
(2021)
Article
Biophysics
N. Balasubramanian, P. Pounpandi, G. Varatharaju, V. Shanmugaiah, K. Balakrishnan, M. A. Thirunarayan
Summary: This study isolated 21 clinical samples of Streptococcus agalactiae from patients in different states of India and found that these pathogenic strains carry six virulence genes and can form biofilms.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Multidisciplinary Sciences
Abebe Aseffa Negeri, Hassen Mamo, Dharmender K. Gahlot, Jyoti M. Gurung, Eyasu Tigabu Seyoum, Matthew S. Francis
Summary: CTX-Ms are widely distributed ESBLs that are encoded by bla(CTX-M) genes. This study found that 75% of CTX-M-producing Escherichia coli isolates in Ethiopian clinical settings carried transmissible plasmids encoding for CTX-Ms. The study also revealed an association between IncF plasmids and the international pandemic E. coli ST131 lineage, suggesting that both horizontal gene transfer and clonal expansion contribute to the rapid and widespread distribution of bla(CTX-M) genes.
SCIENTIFIC REPORTS
(2023)
Article
Microbiology
Yujie Hu, Scott V. Nguyen, Wei Wang, Xin Gan, Yinping Dong, Chang Liu, Xinnan Cui, Jin Xu, Fengqin Li, Seamus Fanning
Summary: The study analyzed the antimicrobial resistance profiles and presence of the mcr-1 gene in 755 foodborne Salmonella strains from 26 provinces of mainland China in 2016. Two isolates carrying mcr-1 were found to express a multidrug-resistant phenotype and the resistance genes were located on different plasmids and chromosomes. This study highlights the concern for mcr-1-carrying Salmonella in terms of antimicrobial resistance and virulence factors, emphasizing the importance of surveillance to prevent dissemination of mcr-encoding genes among foodborne Salmonella.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Clemence Beauruelle, Ludovic Treluyer, Adeline Pastuszka, Thierry Cochard, Clement Lier, Laurent Mereghetti, Philippe Glaser, Claire Poyart, Philippe Lanotte
Summary: In this study, the relevance of a CRISPR-based genotyping tool for Streptococcus agalactiae typing was explored and compared to current molecular methods. Two CRISPR marker schemes were developed, showing high discriminatory power in separating isolates. The method has the advantage of being correlated with MLST and possessing high discriminatory power, with reduced time and cost compared to MLST. This approach could potentially become a reference method for GBS typing.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Rui Yu, Yindi Xu, Stefan Schwarz, Yanhong Shang, Xuezhen Yuan, Yue Zhang, Dexi Li, Xiang-Dang Du
Summary: This study investigated the presence and location of erm(T) in clinical Streptococcus suis isolates and explored the transmission ability and fitness cost of erm(T)-carrying mobile genetic elements. The results showed that erm(T) was detected on a plasmid and an integrative and conjugative element (ICE) in S. suis isolates, which were transmissible by transformation. The erm(T)-carrying plasmid and ICE posed a fitness cost to the host S. suis isolate.
MICROBIOLOGY SPECTRUM
(2022)
Article
Multidisciplinary Sciences
Mohammad Y. Alshahrani, Essam H. Ibrahim, Mohammed Asiri, Mona Kilany, Ali G. Alkhathami, Mohammed N. Alshahrani, Harish C. Chandramoorthy
Summary: The addition of lycopene to the extract enhances the antioxidant and antibacterial activities, showing potential inhibition against multidrug-resistant bacteria.
JOURNAL OF KING SAUD UNIVERSITY SCIENCE
(2022)
Article
Microbiology
Devika Desai, Kelvin G. K. Goh, Matthew J. Sullivan, Debasish Chattopadhyay, Glen C. Ulett
Summary: This study found a higher propensity of hemolytic activity in Group B Streptococcus causing asymptomatic bacteriuria, but no significant differences in biofilm formation abilities among strains with different clinical histories.
INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
(2021)
Article
Fisheries
Defeng Zhang, Zhigang Liu, Yan Ren, Yinggang Wang, Houjun Pan, Dingwu Liang, Weilie Bei, Ouqin Chang, Qing Wang, Cunbin Shi
Summary: This study investigated the phenotype and genotype of GBS strains in tilapia in China from 2006 to 2020, revealing high genetic diversity and an increase in virulence-related genes in prevalent strains in recent years.
Article
Microbiology
Jingxian Liu, Feng Chen, Hongyan Guan, Jiajia Yu, Jing Yu, Jing Zhao, Ying Liu, Lisong Shen
Summary: Streptococcus agalactiae, especially the Ib/CC12 strain, poses a significant threat to young infants with its high mortality rate and multidrug resistance. Prevention and control measures for this infection should be emphasized.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Yong Zhi, Hyun Jung Ji, Jong Hyun Jung, Eui Baek Byun, Woo Sik Kim, Shun Mei Lin, Sangyong Lim, A-Yeung Jang, Min Joo Choi, Ki Bum Ahn, Jae Hyang Lim, Joon Young Song, Ho Seong Seo
Summary: This study analyzed the genotypes of non-srr1/2 GBS clinical isolates collected in South Korea between 2013 and 2016. It identified unique gene clusters associated with multidrug resistance in these strains, and found that their adherence mechanisms and virulence were comparable to Srr1/2-expressing strains.
Article
Infectious Diseases
C. Plainvert, F. El Alaoui, A. Tazi, C. Joubrel, O. Anselem, M. Ballon, A. Frigo, C. Branger, L. Mandelbrot, F. Goffinet, C. Poyart
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
(2018)
Article
Multidisciplinary Sciences
Laetitia Aymeric, Francoise Donnadieu, Celine Mulet, Laurence du Merle, Giulia Nigro, Azadeh Saffarian, Marion Berard, Claire Poyart, Sylvie Robine, Beatrice Regnault, Patrick Trieu-Cuot, Philippe J. Sansonetti, Shaynoor Dramsi
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2018)
Editorial Material
Dermatology
Pascal Del Giudice, Celine Plainvert, Thomas Hubiche, Asmaa Tazi, Agnes Fribourg, Claire Poyart
ACTA DERMATO-VENEREOLOGICA
(2018)
Review
Microbiology
Laura Devaux, Pierre-Alexandre Kaminski, Patrick Trieu-Cuot, Arnaud Firon
CURRENT OPINION IN MICROBIOLOGY
(2018)
Article
Biochemistry & Molecular Biology
Giuseppe Valerio De Gaetano, Giampiero Pietrocola, Letizia Romeo, Roberta Galbo, Germana Lentini, Miriam Giardina, Carmelo Biondo, Angelina Midiri, Giuseppe Mancuso, Mario Venza, Isabella Venza, Arnaud Firon, Patrick Trieu-Cuot, Giuseppe Teti, Pietro Speziale, Concetta Beninati
MOLECULAR MICROBIOLOGY
(2018)
Article
Genetics & Heredity
Laura Devaux, Dona Sleiman, Maria-Vittoria Mazzuoli, Myriam Gominet, Philippe Lanotte, Patrick Trieu-Cuot, Pierre-Alexandre Kaminski, Arnaud Firon
Article
Multidisciplinary Sciences
Elva Bonifacio Andrade, Ana Magalhaes, Ana Puga, Madalena Costa, Joana Bravo, Camila Cabral Portugal, Adilia Ribeiro, Margarida Correia-Neves, Augusto Faustino, Arnaud Firon, Patrick Trieu-Cuot, Teresa Summavielle, Paula Ferreira
NATURE COMMUNICATIONS
(2018)
Article
Immunology
Bruno Perichon, Julie Guignot, Noemi Szili, Cherry Gao, Claire Poyart, Patrick Trieu-Cuot, Shaynoor Dramsi
MICROBES AND INFECTION
(2019)
Article
Immunology
Asmaa Tazi, Celine Plainvert, Olivia Anselem, Morgane Ballon, Valerie Marcou, Aurelien Seco, Fatma El Alaoui, Caroline Joubrel, Najoua El Helali, Emile Falloukh, Amandine Frigo, Josette Raymond, Patrick Trieu-Cuot, Catherine Branger, Alban Le Monnier, Elie Azria, Pierre-Yves Ancel, Pierre Henri Jarreau, Laurent Mandelbrot, Francois Goffinet, Claire Poyart
CLINICAL INFECTIOUS DISEASES
(2019)
Article
Immunology
Mariana Martins, Laurence du Merle, Patrick Trieu-Cuot, Shaynoor Dramsi
MICROBES AND INFECTION
(2020)
Editorial Material
Infectious Diseases
Catarina Magalhaes, Margarida Lima, Patrick Trieu-Cuot, Paula Ferreira
Summary: Sir Alexander Fleming warned against overuse of antibiotics in 1945, and evidence has shown that bacteria can become resistant to almost any available molecule. Prescribing fewer antibiotics and shorter treatment duration can be as effective as longer regimens, reducing selective pressure on microorganisms and delaying the emergence of resistant clones. Further studies are needed to identify optimal antibiotic therapy duration for common infections and clinical biomarkers for guiding antibiotic treatment.
LANCET INFECTIOUS DISEASES
(2021)
Article
Microbiology
Alexis Proutiere, Laurence du Merle, Bruno Perichon, Hugo Varet, Myriam Gominet, Patrick Trieu-Cuot, Shaynoor Dramsi
Summary: Bacteriocins are natural antimicrobial peptides produced by bacteria to kill competitors. Streptococcus gallolyticus subsp. gallolyticus outcompetes commensal enterococci in murine microbiota under tumoral conditions by producing a bacteriocin named gallocin. The regulatory control of gallocin involves a two-peptide system (BlpH/BlpR) activated by a secreted peptide (GSP), with BlpS repressing gallocin gene transcription.
Article
Public, Environmental & Occupational Health
Yu-Jin Jung, Bich-Tram Huynh, Abdoulaye Seck, Raymond Bercion, Fatoumata Diene Sarr, Perlinot Herindrainy, Jean-Baptiste Diouf, Zafitsara Zo Andrianirina, Arnaud Firon, Patrick Trieu-Cuot, Sophie Goyet, Jean-Marc Collard, Elisabeth Delarocque-Astagneau, Didier Guillemot, Muriel Vray
Summary: This study estimated the prevalence of Group B Streptococcus (GBS) colonization among pregnant women in Madagascar and Senegal, and found rates of 5.0% and 16.1% respectively. No sociodemographic characteristics, living conditions, or obstetric history were independently associated with GBS colonization in either country. This community-based study provided valuable information on maternal GBS colonization in these regions.
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE
(2021)
Article
Genetics & Heredity
Maria-Vittoria Mazzuoli, Maelle Daunesse, Hugo Varet, Isabelle Rosinski-Chupin, Rachel Legendre, Odile Sismeiro, Myriam Gominet, Pierre Alexandre Kaminski, Philippe Glaser, Claudia Chica, Patrick Trieu-Cuot, Arnaud Firon
Summary: This study reveals the regulation of virulence genes in Group B Streptococcus by the master regulator CovR and emphasizes the importance of intra-species evolution in the emergence of specific disease-associated clones. The expression of specific surface proteins is linked to the hypervirulence of certain GBS clones.
Article
Immunology
Anne-Sophie Romain, Robert Cohen, Celine Plainvert, Caroline Joubrel, Stephane Bechet, Amelie Perret, Asmaa Tazi, Claire Poyart, Corinne Levy
CLINICAL INFECTIOUS DISEASES
(2018)
