Bacillus anthracis GrlAV96ATopoisomerase IV, a Quinolone Resistance Mutation That Does Not Affect the Water-Metal Ion Bridge

Mechanism of Quinolone Action and Resistance

(2014) Katie J. Aldred et al.   BIOCHEMISTRY

Overcoming Target-Mediated Quinolone Resistance in Topoisomerase IV by Introducing Metal-Ion-Independent Drug–Enzyme Interactions

(2013) Katie J. Aldred et al.   ACS Chemical Biology

Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance

(2013) Katie J. Aldred et al.   NUCLEIC ACIDS RESEARCH

Resistance surveillance studies: a multifaceted problem—the fluoroquinolone example

(2012) A. Dalhoff   INFECTION

Fluoroquinolone and Quinazolinedione Activities against Wild-Type and Gyrase Mutant Strains of Mycobacterium smegmatis

(2011) Muhammad Malik et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Interactions between the Etoposide Derivative F14512 and Human Type II Topoisomerases: Implications for the C4 Spermine Moiety in Promoting Enzyme-Mediated DNA Cleavage

(2011) Amanda C. Gentry et al.   BIOCHEMISTRY

Drug Interactions with Bacillus anthracis Topoisomerase IV: Biochemical Basis for Quinolone Action and Resistance

(2011) Katie J. Aldred et al.   BIOCHEMISTRY

Contribution of mutations in DNA gyrase and topoisomerase IV genes to ciprofloxacin resistance in Escherichia coli clinical isolates

(2011) Sandhya Bansal et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Comparison of In Vitro Activities of Fluoroquinolone-Like 2,4- and 1,3-Diones

(2010) L. M. Oppegard et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Prevalence of Fluoroquinolone Resistance Mechanisms in ColonizingEscherichia coliIsolates Recovered from Hospitalized Patients

(2010) Ebbing Lautenbach et al.   CLINICAL INFECTIOUS DISEASES

Characterization of clinical Escherichia coli isolates from China containing transferable quinolone resistance determinants

(2010) J. Yang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Characterization of the Enzymes Encoded by the Anthrose Biosynthetic Operon of Bacillus anthracis

(2010) S. Dong et al.   JOURNAL OF BACTERIOLOGY

Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance

(2010) Alexandre Wohlkonig et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural Basis of Gate-DNA Breakage and Resealing by Type II Topoisomerases

(2010) Ivan Laponogov et al.   PLoS One

A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs

(2010) E. M. Tretter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Probing the Differential Interactions of Quinazolinedione PD 0305970 and Quinolones with Gyrase and Topoisomerase IV

(2009) X.-S. Pan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

DNA topology and topoisomerases

(2009) Joseph E. Deweese et al.   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

Quinolones: Action and Resistance Updated

(2009) Karl Drlica et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The why and how of DNA unlinking

(2009) Zhirong Liu et al.   NUCLEIC ACIDS RESEARCH

Mechanisms Accounting for Fluoroquinolone Resistance in Escherichia coli Clinical Isolates

(2008) S. K. Morgan-Linnell et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The DNA cleavage reaction of topoisomerase II: wolf in sheep's clothing

(2008) J. E. Deweese et al.   NUCLEIC ACIDS RESEARCH

DNA topoisomerases: harnessing and constraining energy to govern chromosome topology

(2008) Allyn J. Schoeffler et al.   QUARTERLY REVIEWS OF BIOPHYSICS