4.7 Article

Sequence Types 235, 111, and 132 Predominate among Multidrug-Resistant Pseudomonas aeruginosa Clinical Isolates in Croatia

Journal

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
Volume 58, Issue 10, Pages 6277-6283

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/AAC.03116-14

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Funding

  1. FEMS research fellowship [FRF 2009-1]
  2. MIKROBANK from the Polish Ministry of Science and Higher Education

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A population analysis of 103 multidrug-resistant Pseudomonas aeruginosa isolates from Croatian hospitals was performed. Twelve sequence types (STs) were identified, with a predominance of international clones ST235 (serotype O11 [41%]), ST111 (serotype O12 [15%]), and ST132 (serotype O6 [11%]). Overexpression of the natural AmpC cephalosporinase was common (42%), but only a few ST235 or ST111 isolates produced VIM-1 or VIM-2 metallo-beta-lactamases or PER-1 or GES-7 extended-spectrum beta-lactamases.

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