STING Agonists Induce an Innate Antiviral Immune Response against Hepatitis B Virus

Hepatic Immune Regulation and Its Involvement in Viral Hepatitis Infection

(2014) Percy A. Knolle et al.   GASTROENTEROLOGY

Cyclic guanosine monophosphate/adenosine monophosphate synthase (cGAS), innate immune responses, and viral hepatitis

(2014) Eloi R. Verrier et al.   HEPATOLOGY

Cytidine deamination and cccDNA degradation: A new approach for curing HBV?

(2014) Siyuan Ding et al.   HEPATOLOGY

Interferon induction of IFITM proteins promotes infection by human coronavirus OC43

(2014) X. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specific and Nonhepatotoxic Degradation of Nuclear Hepatitis B Virus cccDNA

(2014) J. Lucifora et al.   SCIENCE

Hepatitis B Virus Infection and Immunopathogenesis in a Humanized Mouse Model: Induction of Human-Specific Liver Fibrosis and M2-Like Macrophages

(2014) Moses T. Bility et al.   PLoS Pathogens

Anticancer Flavonoids Are Mouse-Selective STING Agonists

(2013) Sujeong Kim et al.   ACS Chemical Biology

Chronic hepatitis B: What should be the goal for new therapies?

(2013) Timothy M. Block et al.   ANTIVIRAL RESEARCH

A mouse model for HBV immunotolerance and immunotherapy

(2013) Dan Yang et al.   Cellular & Molecular Immunology

Species-specific detection of the antiviral small-molecule compound CMA by STING

(2013) Taner Cavlar et al.   EMBO JOURNAL

GS-9620, an Oral Agonist of Toll-Like Receptor-7, Induces Prolonged Suppression of Hepatitis B Virus in Chronically Infected Chimpanzees

(2013) Robert E. Lanford et al.   GASTROENTEROLOGY

Age-dependent hepatic lymphoid organization directs successful immunity to hepatitis B

(2013) Jean Publicover et al.   JOURNAL OF CLINICAL INVESTIGATION

Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid

(2013) J. Conlon et al.   JOURNAL OF IMMUNOLOGY

Sulfamoylbenzamide Derivatives Inhibit the Assembly of Hepatitis B Virus Nucleocapsids

(2013) M. R. Campagna et al.   JOURNAL OF VIROLOGY

Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity

(2013) John W. Schoggins et al.   NATURE

Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

(2013) X.-D. Li et al.   SCIENCE

Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

(2013) D. Gao et al.   SCIENCE

Alpha-Interferon Suppresses Hepadnavirus Transcription by Altering Epigenetic Modification of cccDNA Minichromosomes

(2013) Fei Liu et al.   PLoS Pathogens

CD40 Activation Rescues Antiviral CD8+ T Cells from PD-1-Mediated Exhaustion

(2013) Masanori Isogawa et al.   PLoS Pathogens

The innate immune response to hepatitis B virus infection: Implications for pathogenesis and therapy

(2012) Jinhong Chang et al.   ANTIVIRAL RESEARCH

STING and the innate immune response to nucleic acids in the cytosol

(2012) Dara L Burdette et al.   NATURE IMMUNOLOGY

Hepatitis B virus–induced lipid alterations contribute to natural killer T cell–dependent protective immunity

(2012) Sebastian Zeissig et al.   NATURE MEDICINE

Anti-TNF drugs in patients with hepatitis B or C virus infection: safety and clinical management

(2011) Mauro Viganò et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Early changes in interferon signaling define natural killer cell response and refractoriness to interferon-based therapy of hepatitis C patients

(2011) Birgit Edlich et al.   HEPATOLOGY

IL-21 is pivotal in determining age-dependent effectiveness of immune responses in a mouse model of human hepatitis B

(2011) Jean Publicover et al.   JOURNAL OF CLINICAL INVESTIGATION

Benefits and risks of nucleoside analog therapy for hepatitis B

(2010) Jules L. Dienstag   HEPATOLOGY

Benefits and risks of interferon therapy for hepatitis B

(2010) Robert Perrillo   HEPATOLOGY

Hepatitis B: The virus and disease

(2010) T. Jake Liang   HEPATOLOGY

Interferons Accelerate Decay of Replication-Competent Nucleocapsids of Hepatitis B Virus

(2010) C. Xu et al.   JOURNAL OF VIROLOGY

Hepatitis B virus suppresses toll-like receptor-mediated innate immune responses in murine parenchymal and nonparenchymal liver cells

(2008) Jun Wu et al.   HEPATOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE