UPC2AIs Required for High-Level Azole Antifungal Resistance in Candida glabrata

Echinocandin and Triazole Antifungal Susceptibility Profiles for Clinical Opportunistic Yeast and Mold Isolates Collected from 2010 to 2011: Application of New CLSI Clinical Breakpoints and Epidemiological Cutoff Values for Characterization of Geographic and Temporal Trends of Antifungal Resistance

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Facultative Sterol Uptake in an Ergosterol-Deficient Clinical Isolate of Candida glabrata Harboring a Missense Mutation inERG11and Exhibiting Cross-Resistance to Azoles and Amphotericin B

(2012) Claire M. Hull et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Impact of Treatment Strategy on Outcomes in Patients with Candidemia and Other Forms of Invasive Candidiasis: A Patient-Level Quantitative Review of Randomized Trials

(2012) D. R. Andes et al.   CLINICAL INFECTIOUS DISEASES

The PATH (Prospective Antifungal Therapy) Alliance® registry and invasive fungal infections: update 2012

(2012) Nkechi Azie et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicans

(2012) Stephanie A. Flowers et al.   EUKARYOTIC CELL

An A643V Amino Acid Substitution in Upc2p Contributes to Azole Resistance in Well-Characterized Clinical Isolates ofCandida albicans

(2010) Samantha J. Hoot et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomewide Expression Profile Analysis of the Candida glabrata Pdr1 Regulon

(2010) Kelly E. Caudle et al.   EUKARYOTIC CELL

TheUPC2Promoter in Candida albicans Contains Twocis-Acting Elements That Bind Directly to Upc2p, Resulting in Transcriptional Autoregulation

(2010) Samantha J. Hoot et al.   EUKARYOTIC CELL

Transcription factors CgUPC2A and CgUPC2B regulate ergosterol biosynthetic genes in Candida glabrata

(2010) Minoru Nagi et al.   GENES TO CELLS

Reverse Genetics in Candida albicans Predicts ARF Cycling Is Essential for Drug Resistance and Virulence

(2010) Elias Epp et al.   PLoS Pathogens

An A643T Mutation in the Transcription Factor Upc2p Causes Constitutive ERG11 Upregulation and Increased Fluconazole Resistance in Candida albicans

(2009) C. J. Heilmann et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Upc2p-associated differential protein expression inCandida albicans

(2009) Christopher F. Hoehamer et al.   PROTEOMICS

Gain of Function Mutations in CgPDR1 of Candida glabrata Not Only Mediate Antifungal Resistance but Also Enhance Virulence

(2009) Sélène Ferrari et al.   PLoS Pathogens

Antifungal Resistance of Candida glabrata Vaginal Isolates and Development of a Quantitative Reverse Transcription-PCR-Based Azole Susceptibility Assay

(2008) S. E. Gygax et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genomewide Location Analysis ofCandida albicansUpc2p, a Regulator of Sterol Metabolism and Azole Drug Resistance

(2008) Sadri Znaidi et al.   EUKARYOTIC CELL

A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate

(2008) Nico Dunkel et al.   EUKARYOTIC CELL

Survey of Vaginal-Flora Candida Species Isolates from Women of Different Age Groups by Use of Species-Specific PCR Detection

(2008) J.-P. Vermitsky et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Candida albicans UPC2 is transcriptionally induced in response to antifungal drugs and anaerobicity through Upc2p-dependent and -independent mechanisms

(2008) S. J. Hoot et al.   MICROBIOLOGY-SGM

A nuclear receptor-like pathway regulating multidrug resistance in fungi

(2008) Jitendra K. Thakur et al.   NATURE