Perturbation of Staphylococcus aureus Gene Expression by the Enoyl-Acyl Carrier Protein Reductase Inhibitor AFN-1252

Community-Associated Methicillin-Resistant Staphylococcus aureus: Trends in Case and Isolate Characteristics from Six Years of Prospective Surveillance

(2017) Kathryn Como-Sabetti et al.   PUBLIC HEALTH REPORTS

Structural Basis for Feed-Forward Transcriptional Regulation of Membrane Lipid Homeostasis in Staphylococcus aureus

(2013) Daniela Albanesi et al.   PLoS Pathogens

Mode of Action,In VitroActivity, andIn VivoEfficacy of AFN-1252, a Selective Antistaphylococcal FabI Inhibitor

(2012) Nachum Kaplan et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Proteomic Signature of Fatty Acid Biosynthesis Inhibition Available for In Vivo Mechanism-of-Action Studies

(2011) Michaela Wenzel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The MUT056399 Inhibitor of FabI Is a New Antistaphylococcal Compound

(2011) S. Escaich et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Modulation of virulence gene expression by cell wall active antibiotics in Staphylococcus aureus

(2011) Natalia Subrt et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Global Changes in Staphylococcus aureus Gene Expression in Human Blood

(2011) Natalia Malachowa et al.   PLoS One

Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors

(2011) J. B. Parsons et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Subinhibitory Concentrations of Protein Synthesis-Inhibiting Antibiotics Promote Increased Expression of the agr Virulence Regulator and Production of Phenol-Soluble Modulin Cytolysins in Community-Associated Methicillin-Resistant Staphylococcus aureus

(2010) H.-S. Joo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Novel Role of Malonyl-ACP in Lipid Homeostasis,

(2010) Mariano A. Martinez et al.   BIOCHEMISTRY

Membrane Thickness Cue for Cold Sensing in a Bacterium

(2010) Larisa E. Cybulski et al.   CURRENT BIOLOGY

In the Staphylococcus aureus Two-Component System sae, the Response Regulator SaeR Binds to a Direct Repeat Sequence and DNA Binding Requires Phosphorylation by the Sensor Kinase SaeS

(2010) F. Sun et al.   JOURNAL OF BACTERIOLOGY

Brinster et al. reply

(2010) Sophie Brinster et al.   NATURE

Essentiality of FASII pathway for Staphylococcus aureus

(2010) Wendy Balemans et al.   NATURE

Importance of the Global Regulators Agr and SaeRS in the Pathogenesis of CA-MRSA USA300 Infection

(2010) Christopher P. Montgomery et al.   PLoS One

Changing the phospholipid composition ofStaphylococcus aureuscauses distinct changes in membrane proteome and membrane-sensory regulators

(2010) Susanne Sievers et al.   PROTEOMICS

AFN-1252, a FabI Inhibitor, Demonstrates a Staphylococcus-Specific Spectrum of Activity

(2009) J. A. Karlowsky et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Influence of Tigecycline on Expression of Virulence Factors in Biofilm-Associated Cells of Methicillin-Resistant Staphylococcus aureus

(2009) K. Smith et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Point Mutation in the Sensor Histidine Kinase SaeS of Staphylococcus aureus Strain Newman Alters the Response to Biocide Exposure

(2009) D. Schafer et al.   JOURNAL OF BACTERIOLOGY

Differential Target Gene Activation by the Staphylococcus aureus Two-Component System saeRS

(2009) M. Mainiero et al.   JOURNAL OF BACTERIOLOGY

The SaeR/S Gene Regulatory System Is Essential for Innate Immune Evasion byStaphylococcus aureus

(2009) Jovanka M. Voyich et al.   JOURNAL OF INFECTIOUS DISEASES

SaeR Binds a Consensus Sequence within Virulence Gene Promoters to Advance USA300 Pathogenesis

(2009) Tyler K. Nygaard et al.   JOURNAL OF INFECTIOUS DISEASES

Transcriptional variation of regulatory and virulence genes due to different media in Staphylococcus aureus

(2009) Binata Ray et al.   MICROBIAL PATHOGENESIS

Global gene expression in Staphylococcus aureus following exposure to alcohol

(2009) Moshe Korem et al.   MICROBIAL PATHOGENESIS

Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

(2009) Sophie Brinster et al.   NATURE

The Virulence Regulator Sae of Staphylococcus aureus: Promoter Activities and Response to Phagocytosis-Related Signals

(2008) T. Geiger et al.   JOURNAL OF BACTERIOLOGY

Regulatory organization of the staphylococcal sae locus

(2008) R. P. Adhikari et al.   MICROBIOLOGY-SGM

A malonyl-CoA-dependent switch in the bacterial response to a dysfunction of lipid metabolism

(2008) Gustavo E. Schujman et al.   MOLECULAR MICROBIOLOGY